Keep tabs on your favorite ETFs with a personalized weekly tracker. Create a Watchlist now →
IDNAvsPBEETF Comparison
iShares Genomics Immunology and Healthcare ETF (IDNA) and Invesco Dynamic Biotechnology & Genome ETF (PBE) belong to the same industry segment: BioTech & Genomics. Both ETFs have the same top 3 sector exposures: and Health Care. IDNA is less expensive with a Total Expense Ratio (TER) of 0.47%, versus 0.58% for PBE. IDNA is up 10.27% year-to-date (YTD) with +$6M in YTD flows. PBE performs worse with -7.11% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of IDNA and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
IDNA vs PBE performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IDNA PBE | +0.52%-5.55% | +10.05%-4.87% | +10.27%-7.11% | +33.25%+17.56% | +29.09%+26.51% | -35.97%+3.80% |
| Flows | IDNA PBE | +$6M-$3M | +$6M+$969K | +$6M+$135K | +$2M-$32M | -$21M-$56M | +$479K-$39M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IDNA PBE | +23.81%+19.01% | +25.77%+22.33% | +24.07%+20.20% | +28.18%+22.79% |
| Max drawdown | IDNA PBE | -7.09%-11.05% | -18.64%-16.18% | -30.61%-22.21% | -68.19%-34.74% |
| Max drawdown duration | IDNA PBE | 11d64d | 127d107d | 279d324d | 1635d1540d |
IDNA | PBE | |
Last sale 3/12/2026 at 1:30 PM | $28.91 | $76.18 |
| Previous close 03/12/2026 | $29.96 | $78.26 |
| Consolidated volume 03/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Create an account to view replication metrics
IDNA | PBE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
IDNA | PBE | |
|---|---|---|
| Last price | $28.91 | $76.18 |
| 1D performance | -3.50% | -2.66% |
| AuM | $150.13 M | $240.98 M |
| E/R | 0.47% | 0.58% |
IDNA | PBE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | iShares | Invesco |
| Benchmark | NYSE FactSet Global Genomics and Immuno Biopharma Index | Dynamic Biotech & Genome Intellidex Index |
| N° of holdings | 42 | 30 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 11, 2019 | June 23, 2005 |
| ESG | No | No |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the IDNA and PBE ETFs performed in 2026?
As of March 12, 2026, IDNA is up 10.27% year-to-date (YTD), while PBE has lost -7.11%. That puts IDNA better performer ahead so far this year.
Which ETF is attracting more investor money: IDNA or PBE?
Year-to-date, the IDNA ETF saw +$6M in flows, compared to +$135K for PBE.
Which ETF is more volatile: IDNA or PBE?
Over the past year, IDNA had a volatility of 25.77%, while PBE experienced 22.33%.
Which ETF is bigger: IDNA or PBE?
As of March 12, 2026, IDNA holds $150.13 M in assets under management (AUM), while PBE manages $240.98 M.
What sectors do the IDNA and PBE ETFs invest in?
IDNA leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.
What are the top holdings of the IDNA ETF and PBE ETF?
IDNA top holdings include MODERNA INC, BAYER AG and REVOLUTION MEDICINES INC. PBE holds in its top three: ILLUMINA, GILEAD SCIENCES and AMGEN-T.
Which ETF is more diversified: IDNA or PBE?
IDNA holds 51 securities with 62.44% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 61.48%.
Have you tried our ETF Compare tool?
Compare ETFs like a pro. Analyze fees, performance, exposure & holdings side-by-side.