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IDNAvsIBBQETF Comparison

ETF 1

IDNA

iShares Genomics Immunology and Healthcare ETF

This fund is part of

BioTech & Genomics

-2.11%

Full IDNA fund page

VS

ETF 2

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

+0.32%

Full IBBQ fund page

iShares Genomics Immunology and Healthcare ETF (IDNA) belongs to the BioTech & Genomics segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. IDNA's top 3 sector exposures are Healthcare and Non-Corporate. In contrast, IBBQ's top sector exposures are Healthcare and Non-Energy Materials. IDNA is more expensive with a Total Expense Ratio (TER) of 0.47%, versus 0.19% for IBBQ. IDNA is up 22.74% year-to-date (YTD) with +$29M in YTD flows. IBBQ performs worse with 14.04% YTD performance, and +$3M in YTD flows. Run a side-by-side ETF comparison of IDNA and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IDNA vs IBBQ performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 07/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	IDNA IBBQ	+1.04%+3.41%	+7.23%+10.20%	+22.74%+14.04%	+45.35%+43.52%	+40.59%+61.16%	-31.37%+32.17%
Flows	IDNA IBBQ	+$13M+$4M	+$16M+$3M	+$29M+$3M	+$25M+$23M	+$4M+$39M	+$10M+$3M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	IDNA IBBQ	+25.18%+22.68%	+23.90%+20.28%	+24.18%+20.24%	+28.01%+21.99%
Max drawdown	IDNA IBBQ	-8.02%-5.97%	-10.60%-8.38%	-29.33%-23.78%	-68.19%-38.09%
Max drawdown duration	IDNA IBBQ	19d17d	46d48d	347d375d	1769d1543d

Trading data

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	IDNA	IBBQ
Last sale 7/27/2026 at 1:30 PM	$32.24	$32.42
Previous close 07/24/2026	$32.03	$32.28
Consolidated volume 07/24/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of June 30, 2026

1-year trailing difference

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	IDNA	IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 7/27/2026 at 1:30 PM

Live

Closed

	IDNA	IBBQ
Last price	$32.24	$32.42
1D performance	+0.66%	+0.43%
AuM	$188.81 M	$75.55 M
E/R	0.47%	0.19%

Characteristics

	IDNA	IBBQ
Management strategy	Passive	Passive
Provider	iShares	Invesco
Benchmark	NYSE FactSet Global Genomics and Immuno Biopharma Index	NASDAQ Biotechnology Index
N° of holdings	48	251
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 11, 2019	June 9, 2021
ESG	No	No

More IDNA data on Trackinsight

More IBBQ data on Trackinsight

Exposure

Countries

IDNA

USA

61.08%

Germany

8.29%

France

7.46%

Other

23.17%

IBBQ

USA

88.1%

Other

11.9%

Sectors

IDNA

Healthcare

99.73%

Other

0.27%

IBBQ

Healthcare

99.98%

Other

0.02%

Diversification

IDNA

Total weight of top 15 holdings out of 15

59.79%

IBBQ

Total weight of top 15 holdings out of 15

49.38%

Top 15 holdings

Data as of June 30, 2026

IDNA

Twist Bioscience Corp.

5.18%

Moderna, Inc.

5.14%

Bayer AG

4.61%

Revolution Medicines, Inc.

4.37%

Genmab A/S

3.88%

Vertex Pharmaceuticals, Inc.

3.87%

Incyte Corp.

3.86%

Merck & Co., Inc.

3.71%

Ipsen SA

3.69%

BioNTech SE

3.68%

ImmunityBio, Inc.

3.60%

Exelixis, Inc.

3.60%

Takeda Pharmaceutical Co., Ltd.

3.59%

GSK Plc

3.53%

Roche Holding AG

3.49%

IBBQ

Vertex Pharmaceuticals, Inc.

8.16%

Amgen, Inc.

7.91%

Gilead Sciences, Inc.

7.07%

Regeneron Pharmaceuticals, Inc.

4.62%

Alnylam Pharmaceuticals, Inc.

2.76%

Revolution Medicines, Inc.

2.74%

Biogen, Inc.

2.26%

Illumina, Inc.

1.89%

Moderna, Inc.

1.89%

Royalty Pharma Plc

1.77%

Roivant Sciences Ltd.

1.74%

argenx SE

1.73%

United Therapeutics Corp.

1.63%

Incyte Corp.

1.61%

Insmed, Inc.

1.59%

Frequently asked questions about IDNA and IBBQ

How have the IDNA and IBBQ ETFs performed in 2026?

As of July 24, 2026, IDNA is up 22.74% year-to-date (YTD), while IBBQ has returned 14.04%. That puts IDNA better performer ahead so far this year.

Which ETF is attracting more investor money: IDNA or IBBQ?

Year-to-date, the IDNA ETF saw +$29M in flows, compared to +$3M for IBBQ.

Which ETF is more volatile: IDNA or IBBQ?

Over the past year, IDNA had a volatility of 23.9%, while IBBQ experienced 20.28%.

Which ETF is bigger: IDNA or IBBQ?

As of July 24, 2026, IDNA holds $188.81 M in assets under management (AUM), while IBBQ manages $75.55 M.

What sectors do the IDNA and IBBQ ETFs invest in?

IDNA leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the IDNA ETF and IBBQ ETF?

IDNA top holdings include Twist Bioscience Corp., Moderna, Inc. and Bayer AG. IBBQ holds in its top three: Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc..

IDNAvsIBBQETF Comparison

iShares Genomics Immunology and Healthcare ETF

Invesco Nasdaq Biotechnology ETF

IDNA vs IBBQ performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the IDNA and IBBQ ETFs performed in 2026?

As of July 24, 2026, IDNA is up 22.74% year-to-date (YTD), while IBBQ has returned 14.04%. That puts IDNA better performer ahead so far this year.

Which ETF is attracting more investor money: IDNA or IBBQ?

Year-to-date, the IDNA ETF saw +$29M in flows, compared to +$3M for IBBQ.

Which ETF is more volatile: IDNA or IBBQ?

Over the past year, IDNA had a volatility of 23.9%, while IBBQ experienced 20.28%.

Which ETF is bigger: IDNA or IBBQ?

As of July 24, 2026, IDNA holds $188.81 M in assets under management (AUM), while IBBQ manages $75.55 M.

What sectors do the IDNA and IBBQ ETFs invest in?

IDNA leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the IDNA ETF and IBBQ ETF?

IDNA top holdings include Twist Bioscience Corp., Moderna, Inc. and Bayer AG. IBBQ holds in its top three: Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc..

Which ETF is more diversified: IDNA or IBBQ?

IDNA holds 48 securities with 59.79% of its assets in the top 15. IBBQ has 251 securities and a top 15 weight of 49.38%.

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