IBRNvsBBPETF Comparison
VS
iShares Neuroscience and Healthcare ETF (IBRN) belongs to the Healthcare Technology segment. Virtus LifeSci Biotech Products ETF (BBP) is part of the Tomorrow's Treatments segment. IBRN's top 2 sector exposures are Healthcare and Non-Corporate. In contrast, BBP's top sector exposures are Healthcare. IBRN is more expensive with a Total Expense Ratio (TER) of 0.47%, versus 0.34% for BBP. IBRN is down -7.37% year-to-date (YTD) with +$2M in YTD flows. BBP performs better with 25.91% YTD performance, and +$66M in YTD flows. Run a side-by-side ETF comparison of IBRN and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
Find out how industry players manage ETF portfolios. Discover our library of Model portfolios
IBRN vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/16/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBRN BBP | -16.95%-1.70% | -19.96%+3.74% | -7.37%+25.91% | +4.69%+39.08% | +45.93%+104.66% | n/a+102.24% |
| Flows | IBRN BBP | -+$5M | +$2M+$26M | +$2M+$66M | +$2M+$78M | +$759K+$83M | -+$76M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBRN BBP | +25.01%+27.34% | +26.48%+26.22% | +25.41%+24.96% | n/a+26.80% |
| Max drawdown | IBRN BBP | -26.38%-8.70% | -26.38%-9.59% | -34.98%-25.54% | n/a-37.61% |
| Max drawdown duration | IBRN BBP | 58d58d | 58d48d | 338d292d | n/a586d |
Trading data
IBRN | BBP | |
Last sale 10/16/2026 at 1:30 PM | $29.97 | $100.20 |
| Previous close 10/15/2026 | $30.72 | $104.56 |
| Consolidated volume 10/15/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
Create an account to view replication metrics
Join for free
IBRN | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Advertisement
Main metrics
Last update 10/16/2026 at 1:30 PM
Live
Closed
IBRN | BBP | |
|---|---|---|
| Last price | $29.97 | $100.20 |
| 1D performance | -2.43% | -4.17% |
| AuM | $5.99 M | $125.54 M |
| E/R | 0.47% | 0.34% |
Characteristics
IBRN | BBP | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | iShares | VIRTUS Investment Partners |
| Benchmark | NYSE FactSet Global Neuro Biopharma and MedTech Index | LifeSci Biotechnology Products Index |
| N° of holdings | 69 | 66 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | August 24, 2022 | December 16, 2014 |
| ESG | No | No |
Advertisement
Exposure
Countries
IBRN
USA
73.41%
Other
26.59%
BBP
USA
85.98%
Other
14.02%
Sectors
IBRN
Healthcare
99.86%
Other
0.14%
BBP
Healthcare
98.44%
Other
1.56%
Advertisement
Diversification
IBRN
Total weight of top 15 holdings out of 15
62.03%
BBP
Total weight of top 15 holdings out of 15
31.08%
Top 15 holdings
Data as of August 31, 2026
IBRN
Praxis Precision Medicines, Inc.
5.21%
Dianthus Therapeutics, Inc.
4.96%
ACADIA Pharmaceuticals, Inc.
4.93%
Scholar Rock Holding Corp.
4.85%
Xenon Pharmaceuticals, Inc.
4.40%
argenx SE
4.37%
Arrowhead Pharmaceuticals, Inc.
4.26%
Biogen, Inc.
4.19%
Alkermes Plc
4.15%
PTC Therapeutics, Inc.
3.70%
Denali Therapeutics, Inc.
3.56%
Neurocrine Biosciences, Inc.
3.55%
Dyne Therapeutics, Inc.
3.38%
Edgewise Therapeutics, Inc.
3.30%
Axsome Therapeutics, Inc.
3.23%
BBP
Moderna, Inc.
3.58%
Crinetics Pharmaceuticals, Inc.
2.94%
Omeros Corp.
2.49%
Iovance Biotherapeutics, Inc.
2.36%
Verastem, Inc.
2.15%
Precigen, Inc.
1.99%
Halozyme Therapeutics, Inc.
1.84%
Zai Lab Ltd.
1.82%
Kiniksa Pharmaceuticals International Plc
1.81%
Kura Oncology, Inc.
1.72%
BeOne Medicines Ltd.
1.70%
Rigel Pharmaceuticals, Inc.
1.69%
Nuvation Bio, Inc.
1.69%
ACADIA Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
Frequently asked questions about IBRN and BBP
How have the IBRN and BBP ETFs performed in 2026?
As of October 16, 2026, IBRN is down -7.37% year-to-date (YTD), while BBP has returned 25.91%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: IBRN or BBP?
Year-to-date, the IBRN ETF saw +$2M in flows, compared to +$66M for BBP.
Which ETF is more volatile: IBRN or BBP?
Over the past year, IBRN had a volatility of 26.48%, while BBP experienced 26.22%.
Which ETF is bigger: IBRN or BBP?
As of October 16, 2026, IBRN holds $5.99 M in assets under management (AUM), while BBP manages $125.54 M.
What sectors do the IBRN and BBP ETFs invest in?
IBRN leans toward sectors like Healthcare. Meanwhile, BBP focuses on Healthcare.
What are the top holdings of the IBRN ETF and BBP ETF?
IBRN top holdings include Praxis Precision Medicines, Inc., Dianthus Therapeutics, Inc. and ACADIA Pharmaceuticals, Inc.. BBP holds in its top three: Moderna, Inc., Crinetics Pharmaceuticals, Inc. and Omeros Corp..
Which ETF is more diversified: IBRN or BBP?
IBRN holds 69 securities with 62.03% of its assets in the top 15. BBP has 66 securities and a top 15 weight of 31.08%.
Advertisement
Advertisement
