IBBQvsXHEETF Comparison
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Invesco Nasdaq Biotechnology ETF (IBBQ) and State Street SPDR S&P Health Care Equipment ETF (XHE) belong to the same industry segment: US Health Care. IBBQ's top 2 sector exposures are Healthcare and Non-Energy Materials. In contrast, XHE's top sector exposures are Healthcare and Finance. IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.35% for XHE. IBBQ is up 22.79% year-to-date (YTD) with +$19M in YTD flows. XHE performs worse with 3.75% YTD performance, and +$9M in YTD flows. Run a side-by-side ETF comparison of IBBQ and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBBQ vs XHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/14/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBBQ XHE | +2.85%-4.09% | +16.89%+11.58% | +22.79%+3.75% | +48.06%+14.15% | +74.15%+10.91% | +36.86%-29.38% |
| Flows | IBBQ XHE | +$13M+$240K | +$18M+$9M | +$19M+$9M | +$38M+$2M | +$54M-$267M | +$28M-$384M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBBQ XHE | +23.84%+24.49% | +21.54%+22.67% | +20.91%+22.25% | +22.08%+24.85% |
| Max drawdown | IBBQ XHE | -6.48%-7.53% | -8.38%-18.20% | -23.78%-24.35% | -37.23%-49.37% |
| Max drawdown duration | IBBQ XHE | 26d26d | 48d207d | 375d565d | 1485d1776d |
Trading data
IBBQ | XHE | |
Last sale 9/15/2026 at 1:30 PM | $34.19 | $91.10 |
| Previous close 09/14/2026 | $34.82 | $91.43 |
| Consolidated volume 09/14/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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IBBQ | XHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/15/2026 at 1:30 PM
Live
Closed
IBBQ | XHE | |
|---|---|---|
| Last price | $34.19 | $91.10 |
| 1D performance | -1.81% | -0.36% |
| AuM | $96.64 M | $169.14 M |
| E/R | 0.19% | 0.35% |
Characteristics
IBBQ | XHE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | State Street Investment Management |
| Benchmark | NASDAQ Biotechnology Index | S&P Health Care Equipment Select Industry Index |
| N° of holdings | 249 | 66 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 9, 2021 | January 26, 2011 |
| ESG | No | No |
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Exposure
Countries
IBBQ
USA
88.05%
Other
11.95%
XHE
USA
93.56%
Other
6.44%
Sectors
IBBQ
Healthcare
99.91%
Other
0.09%
XHE
Healthcare
98.72%
Other
1.28%
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Diversification
IBBQ
Total weight of top 15 holdings out of 15
50.47%
XHE
Total weight of top 15 holdings out of 15
30.19%
Top 15 holdings
Data as of July 31, 2026
IBBQ
Amgen, Inc.
8.55%
Vertex Pharmaceuticals, Inc.
8.03%
Gilead Sciences, Inc.
7.34%
Regeneron Pharmaceuticals, Inc.
5.08%
Revolution Medicines, Inc.
2.73%
Alnylam Pharmaceuticals, Inc.
2.71%
Biogen, Inc.
2.19%
Illumina, Inc.
2.09%
Royalty Pharma Plc
1.86%
Incyte Corp.
1.80%
argenx SE
1.73%
Roivant Sciences Ltd.
1.68%
Insmed, Inc.
1.58%
United Therapeutics Corp.
1.58%
Moderna, Inc.
1.53%
XHE
AtriCure, Inc.
2.14%
Glaukos Corp.
2.13%
Dentsply Sirona, Inc.
2.08%
Enovis Corp.
2.07%
Integer Holdings Corp.
2.07%
Butterfly Network, Inc.
2.06%
Neogen Corp.
2.05%
Artivion, Inc.
2.05%
Baxter International, Inc.
2.01%
CONMED Corp.
1.99%
Merit Medical Systems, Inc.
1.98%
QuidelOrtho Corp.
1.94%
ICU Medical, Inc.
1.88%
Tandem Diabetes Care, Inc.
1.88%
Inspire Medical Systems, Inc.
1.85%
Frequently asked questions about IBBQ and XHE
How have the IBBQ and XHE ETFs performed in 2026?
As of September 14, 2026, IBBQ is up 22.79% year-to-date (YTD), while XHE has returned 3.75%. That puts IBBQ better performer ahead so far this year.
Which ETF is attracting more investor money: IBBQ or XHE?
Year-to-date, the IBBQ ETF saw +$19M in flows, compared to +$9M for XHE.
Which ETF is more volatile: IBBQ or XHE?
Over the past year, IBBQ had a volatility of 21.54%, while XHE experienced 22.67%.
Which ETF is bigger: IBBQ or XHE?
As of September 14, 2026, IBBQ holds $96.64 M in assets under management (AUM), while XHE manages $169.14 M.
What sectors do the IBBQ and XHE ETFs invest in?
IBBQ leans toward sectors like Healthcare. Meanwhile, XHE focuses on Healthcare.
What are the top holdings of the IBBQ ETF and XHE ETF?
IBBQ top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. XHE holds in its top three: AtriCure, Inc., Glaukos Corp. and Dentsply Sirona, Inc..
Which ETF is more diversified: IBBQ or XHE?
IBBQ holds 249 securities with 50.47% of its assets in the top 15. XHE has 66 securities and a top 15 weight of 30.19%.
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