IBBQvsWDNAETF Comparison
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Invesco Nasdaq Biotechnology ETF (IBBQ) belongs to the US Health Care segment. WisdomTree BioRevolution Fund (WDNA) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: Healthcare and Non-Energy Materials. IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.45% for WDNA. IBBQ is up 15.4% year-to-date (YTD) with +$3M in YTD flows. WDNA performs better with 17.63% YTD performance, and -$357K in YTD flows. Run a side-by-side ETF comparison of IBBQ and WDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IBBQ vs WDNA performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/30/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IBBQ WDNA | +0.10%-3.40% | +12.21%+11.93% | +15.40%+17.63% | +46.91%+47.23% | +62.42%+14.80% | +32.40%-18.07% |
| Flows | IBBQ WDNA | +$4M- | +$3M- | +$3M-$357K | +$23M-$357K | +$39M-$524K | +$11M+$1M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IBBQ WDNA | +22.34%+23.55% | +20.29%+25.18% | +20.25%+25.05% | +21.96%+24.97% |
| Max drawdown | IBBQ WDNA | -5.97%-8.80% | -8.38%-11.90% | -23.78%-37.36% | -38.09%-58.58% |
| Max drawdown duration | IBBQ WDNA | 23d23d | 48d147d | 375d876d | 1543d1792d |
Trading data
IBBQ | WDNA | |
Last sale 7/31/2026 at 3:25 PM | $31.97 | $19.91 |
| Previous close 07/30/2026 | $32.70 | $19.57 |
| Consolidated volume 07/30/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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IBBQ | WDNA | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/31/2026 at 3:25 PM
Live
Closed
IBBQ | WDNA | |
|---|---|---|
| Last price | $31.97 | $19.91 |
| 1D performance | -2.24% | +1.73% |
| AuM | $76.45 M | $2.59 M |
| E/R | 0.19% | 0.45% |
Characteristics
IBBQ | WDNA | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | WisdomTree |
| Benchmark | NASDAQ Biotechnology Index | WisdomTree BioRevolution Index |
| N° of holdings | 251 | 80 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 9, 2021 | June 3, 2021 |
| ESG | No | No |
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Exposure
Countries
IBBQ
USA
88.1%
Other
11.9%
WDNA
USA
83.72%
Other
16.28%
Sectors
IBBQ
Healthcare
99.98%
Other
0.02%
WDNA
Healthcare
89.22%
Other
10.78%
Diversification
IBBQ
Total weight of top 15 holdings out of 15
49.38%
WDNA
Total weight of top 15 holdings out of 15
39.68%
Top 15 holdings
Data as of June 30, 2026
IBBQ
Vertex Pharmaceuticals, Inc.
8.16%
Amgen, Inc.
7.91%
Gilead Sciences, Inc.
7.07%
Regeneron Pharmaceuticals, Inc.
4.62%
Alnylam Pharmaceuticals, Inc.
2.76%
Revolution Medicines, Inc.
2.74%
Biogen, Inc.
2.26%
Illumina, Inc.
1.89%
Moderna, Inc.
1.89%
Royalty Pharma Plc
1.77%
Roivant Sciences Ltd.
1.74%
argenx SE
1.73%
United Therapeutics Corp.
1.63%
Incyte Corp.
1.61%
Insmed, Inc.
1.59%
WDNA
Twist Bioscience Corp.
5.81%
Eli Lilly & Co.
3.98%
Moderna, Inc.
3.67%
Johnson & Johnson
2.98%
United Therapeutics Corp.
2.55%
Natera, Inc.
2.32%
Tempus AI, Inc.
2.25%
Immunome, Inc.
2.15%
Beam Therapeutics, Inc.
2.14%
Stoke Therapeutics, Inc.
2.02%
Corteva, Inc.
1.99%
Structure Therapeutics, Inc.
1.98%
Krystal Biotech, Inc.
1.97%
Darling Ingredients, Inc.
1.96%
Ionis Pharmaceuticals, Inc.
1.91%
Frequently asked questions about IBBQ and WDNA
How have the IBBQ and WDNA ETFs performed in 2026?
As of July 30, 2026, IBBQ is up 15.4% year-to-date (YTD), while WDNA has returned 17.63%. That puts WDNA better performer ahead so far this year.
Which ETF is attracting more investor money: IBBQ or WDNA?
Year-to-date, the IBBQ ETF saw +$3M in flows, compared to -$357K for WDNA.
Which ETF is more volatile: IBBQ or WDNA?
Over the past year, IBBQ had a volatility of 20.29%, while WDNA experienced 25.18%.
Which ETF is bigger: IBBQ or WDNA?
As of July 30, 2026, IBBQ holds $76.45 M in assets under management (AUM), while WDNA manages $2.59 M.
What sectors do the IBBQ and WDNA ETFs invest in?
IBBQ leans toward sectors like Healthcare. Meanwhile, WDNA focuses on Healthcare.
What are the top holdings of the IBBQ ETF and WDNA ETF?
IBBQ top holdings include Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc.. WDNA holds in its top three: Twist Bioscience Corp., Eli Lilly & Co. and Moderna, Inc..
Which ETF is more diversified: IBBQ or WDNA?
IBBQ holds 251 securities with 49.38% of its assets in the top 15. WDNA has 80 securities and a top 15 weight of 39.68%.
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