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IBBQvsTMEDETF Comparison

ETF 1
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-0.44%
VS
ETF 2
TMED

T. Rowe Price Health Care ETF

This fund is part of
US Health Care
-0.44%

Invesco Nasdaq Biotechnology ETF (IBBQ) and T. Rowe Price Health Care ETF (TMED) belong to the same industry segment: US Health Care. IBBQ's top 2 sector exposures are Healthcare and Non-Energy Materials. In contrast, TMED's top sector exposures are Healthcare, Consumer Non-Cyclicals and Non-Corporate. IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.44% for TMED. IBBQ is up 21.06% year-to-date (YTD) with +$19M in YTD flows. TMED performs worse with 15.44% YTD performance, and +$13M in YTD flows. Run a side-by-side ETF comparison of IBBQ and TMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IBBQ vs TMED performance and flow charts

Performance

-4.0-2.00.02.04.06.08.0%Aug 14Aug 21Aug 28Sep 4Sep 11

Cumulative Flows

0 M2 M4 M6 M8 M10 M12 M14 MAug 14Aug 21Aug 28Sep 4Sep 11

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 09/15/2026
1M3MYTD1Y3Y5Y
Perf.
IBBQ
TMED
-0.02%-2.57%
+15.24%+7.69%
+21.06%+15.44%
+45.96%+34.35%
+73.10%n/a
+33.62%n/a
Flows
IBBQ
TMED
+$13M+$4M
+$18M+$9M
+$19M+$13M
+$38M+$15M
+$54M-
+$28M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
IBBQ
TMED
+23.89%+18.16%
+21.55%+18.40%
+20.92%n/a
+22.09%n/a
Max drawdown
IBBQ
TMED
-6.89%-7.92%
-8.38%-11.09%
-23.78%n/a
-37.23%n/a
Max drawdown duration
IBBQ
TMED
27d26d
48d125d
375dn/a
1485dn/a
Trading data

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IBBQ
TMED
Last sale
9/16/2026 at 1:30 PM
$34.36
$33.90
Previous close
09/15/2026
$34.25
$33.92
Consolidated volume
09/15/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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TMED
is actively managed and doesn’t replicate an index

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IBBQ
TMED
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
Main metrics
Last update 9/16/2026 at 1:30 PM
Live
Closed
IBBQ
TMED
Last price
$34.36
$33.90
1D performance
+0.31%
-0.04%
AuM$95.27 M$32.55 M
E/R0.19%0.44%
Characteristics
IBBQ
TMED
Management strategyPassiveActive
ProviderInvescoT. Rowe Price
BenchmarkNASDAQ Biotechnology Index-
N° of holdings24997
Asset classEquities-
Trailing 12m distribution yield
Join
Join
Inception dateJune 9, 2021June 11, 2025
ESGNoNo
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Exposure

Countries

IBBQ
USA
88.05%
Other
11.95%
TMED
USA
93.59%
Other
6.41%

Sectors

IBBQ
Healthcare
99.91%
Other
0.09%
TMED
Healthcare
98.58%
Other
1.42%
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Diversification

IBBQ

Total weight of top 15 holdings out of 15

50.47%
TMED

Total weight of top 15 holdings out of 15

61.11%

Top 15 holdings

Data as of July 31, 2026
IBBQ
Amgen, Inc.
8.55%
Vertex Pharmaceuticals, Inc.
8.03%
Gilead Sciences, Inc.
7.34%
Regeneron Pharmaceuticals, Inc.
5.08%
Revolution Medicines, Inc.
2.73%
Alnylam Pharmaceuticals, Inc.
2.71%
Biogen, Inc.
2.19%
Illumina, Inc.
2.09%
Royalty Pharma Plc
1.86%
Incyte Corp.
1.80%
argenx SE
1.73%
Roivant Sciences Ltd.
1.68%
Insmed, Inc.
1.58%
United Therapeutics Corp.
1.58%
Moderna, Inc.
1.53%
TMED
Eli Lilly & Co.
16.65%
UnitedHealth Group, Inc.
5.89%
Thermo Fisher Scientific, Inc.
4.44%
Alnylam Pharmaceuticals, Inc.
4.11%
Gilead Sciences, Inc.
3.76%
Danaher Corp.
3.58%
Cencora, Inc.
3.30%
Insulet Corp.
2.73%
Agilent Technologies, Inc.
2.69%
DexCom, Inc.
2.66%
Dyne Therapeutics, Inc.
2.60%
Stryker Corp.
2.49%
West Pharmaceutical Services, Inc.
2.29%
Waters Corp.
2.20%
McKesson Corp.
1.72%
Frequently asked questions about IBBQ and TMED

How have the IBBQ and TMED ETFs performed in 2026?

As of September 15, 2026, IBBQ is up 21.06% year-to-date (YTD), while TMED has returned 15.44%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or TMED?

Year-to-date, the IBBQ ETF saw +$19M in flows, compared to +$13M for TMED.

Which ETF is more volatile: IBBQ or TMED?

Over the past year, IBBQ had a volatility of 21.55%, while TMED experienced 18.4%.

Which ETF is bigger: IBBQ or TMED?

As of September 15, 2026, IBBQ holds $95.27 M in assets under management (AUM), while TMED manages $32.55 M.

What sectors do the IBBQ and TMED ETFs invest in?

IBBQ leans toward sectors like Healthcare. Meanwhile, TMED focuses on Healthcare.

What are the top holdings of the IBBQ ETF and TMED ETF?

IBBQ top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. TMED holds in its top three: Eli Lilly & Co., UnitedHealth Group, Inc. and Thermo Fisher Scientific, Inc..

Which ETF is more diversified: IBBQ or TMED?

IBBQ holds 249 securities with 50.47% of its assets in the top 15. TMED has 97 securities and a top 15 weight of 61.11%.

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