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IBBQvsPBEETF Comparison

ETF 1

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

+1.21%

Full IBBQ fund page

VS

ETF 2

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

+2.4%

Full PBE fund page

Invesco Nasdaq Biotechnology ETF (IBBQ) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. IBBQ's top 2 sector exposures are Healthcare and Non-Energy Materials. In contrast, PBE's top sector exposures are Healthcare. IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.59% for PBE. IBBQ is up 22.79% year-to-date (YTD) with +$19M in YTD flows. PBE performs worse with 15.35% YTD performance, and +$114M in YTD flows. Run a side-by-side ETF comparison of IBBQ and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IBBQ vs PBE performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 09/14/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	IBBQ PBE	+2.85%-0.03%	+16.89%+11.40%	+22.79%+15.35%	+48.06%+37.16%	+74.15%+58.59%	+36.86%+26.94%
Flows	IBBQ PBE	+$13M+$27M	+$18M+$117M	+$19M+$114M	+$38M+$113M	+$54M+$62M	+$28M+$64M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	IBBQ PBE	+23.84%+19.39%	+21.54%+19.15%	+20.91%+20.49%	+22.08%+22.56%
Max drawdown	IBBQ PBE	-6.48%-5.97%	-8.38%-11.70%	-23.78%-22.21%	-37.23%-33.32%
Max drawdown duration	IBBQ PBE	26d11d	48d166d	375d324d	1485d1509d

Trading data

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	IBBQ	PBE
Last sale 9/15/2026 at 1:30 PM	$34.19	$92.94
Previous close 09/14/2026	$34.82	$93.64
Consolidated volume 09/14/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of August 31, 2026

1-year trailing difference

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	IBBQ	PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 9/15/2026 at 1:30 PM

Live

Closed

	IBBQ	PBE
Last price	$34.19	$92.94
1D performance	-1.81%	-0.75%
AuM	$96.64 M	$408.56 M
E/R	0.19%	0.59%

Characteristics

	IBBQ	PBE
Management strategy	Passive	Passive
Provider	Invesco	Invesco
Benchmark	NASDAQ Biotechnology Index	Dynamic Biotech & Genome Intellidex Index
N° of holdings	249	30
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 9, 2021	June 23, 2005
ESG	No	No

More IBBQ data on Trackinsight

More PBE data on Trackinsight

Exposure

Countries

IBBQ

USA

88.05%

Other

11.95%

PBE

USA

97.13%

Other

2.87%

Sectors

IBBQ

Healthcare

99.91%

Other

0.09%

PBE

Healthcare

100%

Other

0%

Diversification

IBBQ

Total weight of top 15 holdings out of 15

50.47%

PBE

Total weight of top 15 holdings out of 15

61.32%

Top 15 holdings

Data as of July 31, 2026

IBBQ

Amgen, Inc.

8.55%

Vertex Pharmaceuticals, Inc.

8.03%

Gilead Sciences, Inc.

7.34%

Regeneron Pharmaceuticals, Inc.

5.08%

Revolution Medicines, Inc.

2.73%

Alnylam Pharmaceuticals, Inc.

2.71%

Biogen, Inc.

2.19%

Illumina, Inc.

2.09%

Royalty Pharma Plc

1.86%

Incyte Corp.

1.80%

argenx SE

1.73%

Roivant Sciences Ltd.

1.68%

Insmed, Inc.

1.58%

United Therapeutics Corp.

1.58%

Moderna, Inc.

1.53%

PBE

Amgen, Inc.

5.16%

Vertex Pharmaceuticals, Inc.

4.96%

Royalty Pharma Plc

4.91%

Regeneron Pharmaceuticals, Inc.

4.90%

Biogen, Inc.

4.85%

Gilead Sciences, Inc.

4.44%

Alnylam Pharmaceuticals, Inc.

4.34%

United Therapeutics Corp.

4.06%

CareDx, Inc.

4.01%

Bio-Techne Corp.

3.66%

Illumina, Inc.

3.27%

Vericel Corp.

3.25%

Protagonist Therapeutics, Inc.

3.24%

Incyte Corp.

3.19%

Veracyte, Inc.

3.07%

Frequently asked questions about IBBQ and PBE

How have the IBBQ and PBE ETFs performed in 2026?

As of September 14, 2026, IBBQ is up 22.79% year-to-date (YTD), while PBE has returned 15.35%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or PBE?

Year-to-date, the IBBQ ETF saw +$19M in flows, compared to +$114M for PBE.

Which ETF is more volatile: IBBQ or PBE?

Over the past year, IBBQ had a volatility of 21.54%, while PBE experienced 19.15%.

Which ETF is bigger: IBBQ or PBE?

As of September 14, 2026, IBBQ holds $96.64 M in assets under management (AUM), while PBE manages $408.56 M.

What sectors do the IBBQ and PBE ETFs invest in?

IBBQ leans toward sectors like Healthcare. Meanwhile, PBE focuses on Healthcare.

What are the top holdings of the IBBQ ETF and PBE ETF?

IBBQ top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. PBE holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Royalty Pharma Plc.

IBBQvsPBEETF Comparison

Invesco Nasdaq Biotechnology ETF

Invesco Dynamic Biotechnology & Genome ETF

IBBQ vs PBE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the IBBQ and PBE ETFs performed in 2026?

As of September 14, 2026, IBBQ is up 22.79% year-to-date (YTD), while PBE has returned 15.35%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or PBE?

Year-to-date, the IBBQ ETF saw +$19M in flows, compared to +$114M for PBE.

Which ETF is more volatile: IBBQ or PBE?

Over the past year, IBBQ had a volatility of 21.54%, while PBE experienced 19.15%.

Which ETF is bigger: IBBQ or PBE?

As of September 14, 2026, IBBQ holds $96.64 M in assets under management (AUM), while PBE manages $408.56 M.

What sectors do the IBBQ and PBE ETFs invest in?

IBBQ leans toward sectors like Healthcare. Meanwhile, PBE focuses on Healthcare.

What are the top holdings of the IBBQ ETF and PBE ETF?

IBBQ top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. PBE holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Royalty Pharma Plc.

Which ETF is more diversified: IBBQ or PBE?

IBBQ holds 249 securities with 50.47% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 61.32%.

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