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IBBQvsPBEETF Comparison

ETF 1
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-0.3%
Full IBBQ fund page
VS
ETF 2
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
-0.05%
Full PBE fund page

Invesco Nasdaq Biotechnology ETF (IBBQ) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. IBBQ's top 3 sector exposures are Health Care and Consumer Staples. In contrast, PBE's top sector exposures are Health Care  IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.58% for PBE. IBBQ is up 0.27% year-to-date (YTD) with +$8M in YTD flows. PBE performs worse with -7.12% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of IBBQ and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IBBQ vs PBE performance and flow charts

Performance

-6.0-4.0-2.00.02.0%Feb 13Feb 23Mar 2Mar 9

Cumulative Flows

-3.5 M-3 M-2.5 M-2 M-1.5 M-1 M-0.5 M0 MFeb 13Feb 23Mar 2Mar 9

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/13/2026
1M3MYTD1Y3Y5Y
Perf.
IBBQ
PBE
-3.33%-6.52%
+0.23%-5.52%
+0.27%-7.12%
+30.20%+19.22%
+46.15%+26.51%
n/a+1.84%
Flows
IBBQ
PBE
--$3M
+$12M+$969K
+$8M+$135K
+$21M-$32M
+$41M-$56M
--$39M
Volatility and drawdown
3M1Y3Y5Y
Volatility
IBBQ
PBE
+20.67%+18.95%
+23.15%+22.28%
+19.29%+20.18%
n/a+22.77%
Max drawdown
IBBQ
PBE
-5.64%-11.05%
-17.24%-16.18%
-23.78%-22.21%
n/a-34.74%
Max drawdown duration
IBBQ
PBE
17d65d
127d107d
375d324d
n/a1540d
Trading data

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IBBQ
PBE
Last sale
3/13/2026 at 1:30 PM
$28.46
$76.18
Previous close
03/12/2026
$28.59
$76.18
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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IBBQ
PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
IBBQ
PBE
Last price
$28.46
$76.18
1D performance
-0.46%
+0.00%
AuM$71.71 M$240.98 M
E/R0.19%0.58%
Characteristics
IBBQ
PBE
Management strategyPassivePassive
ProviderInvescoInvesco
BenchmarkNASDAQ Biotechnology IndexDynamic Biotech & Genome Intellidex Index
N° of holdings19630
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateJune 9, 2021June 23, 2005
ESGNoNo
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Exposure

Countries

IBBQ
USA
93.84%
Other
6.16%
PBE
USA
94.25%
Other
5.75%

Sectors

IBBQ
Health Care
85.82%
Other
14.18%
PBE
Health Care
96.95%
Other
3.05%
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Diversification

IBBQ

Total weight of top 15 holdings out of 15

52.08%
PBE

Total weight of top 15 holdings out of 15

61.48%

Top 15 holdings

Data as of January 31, 2026
IBBQ
VERTEX PHARMACEUTICALS
8.96%
GILEAD SCIENCES
8.92%
AMGEN-T
8.25%
REGENERON PHARMACEUTICALS
5.90%
ALNYLAM PHARMACEUTICALS
3.58%
INSMED
2.55%
BIOGEN INC
1.90%
US04016X1019
1.82%
ILLUMINA
1.75%
UTD THERAPEUT
1.53%
INCYTE
1.51%
REVOLUTION MEDICINES INC
1.42%
MODERNA INC
1.41%
ROYALTY PHARMA
1.30%
MEDPACE HOLDINGS INC
1.27%
PBE
ILLUMINA
5.91%
GILEAD SCIENCES
5.35%
AMGEN-T
5.09%
REGENERON PHARMACEUTICALS
4.87%
UTD THERAPEUT
4.83%
BIOGEN INC
4.76%
INCYTE
4.70%
ALNYLAM PHARMACEUTICALS
4.05%
AMICUS THERAPEUTICS
3.83%
DYNAVAX TECHNOLOGIES
3.60%
NL0015002SN0
3.05%
ACADIA PHARMACEUTICALS
2.98%
MANNKIND
2.89%
BIO-TECHNE CORP
2.83%
EXELIXIS
2.74%
Frequently asked questions about IBBQ and PBE

How have the IBBQ and PBE ETFs performed in 2026?

As of March 13, 2026, IBBQ is up 0.27% year-to-date (YTD), while PBE has lost -7.12%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or PBE?

Year-to-date, the IBBQ ETF saw +$8M in flows, compared to +$135K for PBE.

Which ETF is more volatile: IBBQ or PBE?

Over the past year, IBBQ had a volatility of 23.15%, while PBE experienced 22.28%.

Which ETF is bigger: IBBQ or PBE?

As of March 13, 2026, IBBQ holds $71.71 M in assets under management (AUM), while PBE manages $240.98 M.

What sectors do the IBBQ and PBE ETFs invest in?

IBBQ leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the IBBQ ETF and PBE ETF?

IBBQ top holdings include VERTEX PHARMACEUTICALS, GILEAD SCIENCES and AMGEN-T. PBE holds in its top three: ILLUMINA, GILEAD SCIENCES and AMGEN-T.

Which ETF is more diversified: IBBQ or PBE?

IBBQ holds 262 securities with 52.08% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 61.48%.

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