NYSE CRTR Economy Event Watch the replay →

Advertisement
Advertisement

IBBQvsPBEETF Comparison

ETF 1
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-0%
VS
ETF 2
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
-0.39%

Invesco Nasdaq Biotechnology ETF (IBBQ) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. IBBQ's top 3 sector exposures are Health Care and Consumer Staples. In contrast, PBE's top sector exposures are Health Care  IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.58% for PBE. IBBQ is up 4.28% year-to-date (YTD) with +$290K in YTD flows. PBE performs worse with 2.54% YTD performance, and -$3M in YTD flows. Run a side-by-side ETF comparison of IBBQ and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

Find out how industry players manage ETF portfolios.  Discover our library of Model portfolios

IBBQ vs PBE performance and flow charts

Performance

-4.0-2.00.02.0%May 12May 19May 27Jun 3Jun 10

Cumulative Flows

0 M10 M20 M30 M40 M50 M60 MMay 12May 19May 27Jun 3Jun 10

Get all the metrics on this page, and more, through a reliable ETF data feed

Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 06/12/2026
1M3MYTD1Y3Y5Y
Perf.
IBBQ
PBE
-0.92%+1.33%
+3.50%+10.39%
+4.28%+2.54%
+38.30%+31.31%
+45.10%+34.96%
+20.89%+10.44%
Flows
IBBQ
PBE
-+$2M
-$8M-$3M
+$290K-$3M
+$15M-$26M
+$33M-$56M
+$59M-$45M
Volatility and drawdown
3M1Y3Y5Y
Volatility
IBBQ
PBE
+24.17%+19.82%
+20.28%+19.09%
+20.02%+20.14%
+21.89%+22.41%
Max drawdown
IBBQ
PBE
-6.92%-4.08%
-8.38%-11.70%
-23.78%-22.21%
-38.09%-34.74%
Max drawdown duration
IBBQ
PBE
54d16d
48d156d
375d324d
1543d1540d
Trading data

Create an account to view trading data

Join for free
IBBQ
PBE
Last sale
6/12/2026 at 7:59 PM
$29.54
$84.10
Previous close
06/12/2026
$29.50
$84.82
Consolidated volume
06/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of May 29, 2026
1-year trailing difference

Create an account to view replication metrics

Join for free

Create an account to view replication quality

Join for free
IBBQ
PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
Advertisement
Main metrics
Last update 6/12/2026 at 7:59 PM
Live
Closed
IBBQ
PBE
Last price
$29.54
$84.10
1D performance
+0.14%
-0.85%
AuM$66.80 M$259.85 M
E/R0.19%0.58%
Characteristics
IBBQ
PBE
Management strategyPassivePassive
ProviderInvescoInvesco
BenchmarkNASDAQ Biotechnology IndexDynamic Biotech & Genome Intellidex Index
N° of holdings19030
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
Join
Inception dateJune 9, 2021June 23, 2005
ESGNoNo
Advertisement
Exposure

Countries

IBBQ
USA
91.42%
Other
8.58%
PBE
USA
92.2%
Other
7.8%

Sectors

IBBQ
Health Care
84.62%
Other
15.38%
PBE
Health Care
97.78%
Other
2.22%

Diversification

IBBQ

Total weight of top 15 holdings out of 15

49.38%
PBE

Total weight of top 15 holdings out of 15

62.95%

Top 15 holdings

Data as of April 30, 2026
IBBQ
AMGEN-T
7.26%
GILEAD SCIENCES
7.11%
VERTEX PHARMACEUTICALS
7.11%
REGENERON PHARMACEUTICALS
6.23%
ALNYLAM PHARMACEUTICALS
3.30%
INSMED
2.36%
BIOGEN INC
2.14%
REVOLUTION MEDICINES INC
2.10%
UTD THERAPEUT
2.00%
US04016X1019
1.79%
ROYALTY PHARMA
1.71%
ROIVANT SCIENCES LTD
1.60%
ILLUMINA
1.58%
MODERNA INC
1.55%
INCYTE
1.53%
PBE
UTD THERAPEUT
6.20%
ILLUMINA
5.42%
REGENERON PHARMACEUTICALS
4.99%
INCYTE
4.91%
ALNYLAM PHARMACEUTICALS
4.80%
BIOGEN INC
4.80%
AMGEN-T
4.60%
GILEAD SCIENCES
4.48%
CATALYST PHARMACEUTICALS INC
3.42%
BIOCRYST PHARMACEUTICALS
3.30%
TG THERAPEUTICS
3.28%
ARROWHEAD PHARMACEUTICALS INC
3.27%
CAREDX INC/D
3.21%
PROTAGONIST THERAPEUTICS INC
3.18%
ROYALTY PHARMA
3.09%
Frequently asked questions about IBBQ and PBE

How have the IBBQ and PBE ETFs performed in 2026?

As of June 12, 2026, IBBQ is up 4.28% year-to-date (YTD), while PBE has returned 2.54%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or PBE?

Year-to-date, the IBBQ ETF saw +$290K in flows, compared to -$3M for PBE.

Which ETF is more volatile: IBBQ or PBE?

Over the past year, IBBQ had a volatility of 20.28%, while PBE experienced 19.09%.

Which ETF is bigger: IBBQ or PBE?

As of June 12, 2026, IBBQ holds $66.80 M in assets under management (AUM), while PBE manages $259.85 M.

What sectors do the IBBQ and PBE ETFs invest in?

IBBQ leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the IBBQ ETF and PBE ETF?

IBBQ top holdings include AMGEN-T, GILEAD SCIENCES and VERTEX PHARMACEUTICALS. PBE holds in its top three: UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS.

Which ETF is more diversified: IBBQ or PBE?

IBBQ holds 255 securities with 49.38% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 62.95%.

Advertisement
Advertisement
Advertisement
ETF INVESTOR RESOURCES

Expert-Built ETF Portfolios, All in One Place

Don’t start from scratch. Discover ready-made ETF portfolios built by professionals to match different goals, timelines, and market views. Use them as inspiration or as a starting point for your own allocation.

Portfolio Builder