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IBBQvsGNOMETF Comparison

ETF 1
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-2%
Full IBBQ fund page
VS
ETF 2
GNOM

Global X Genomics & Biotechnology ETF - USD

This fund is part of
BioTech & Genomics
-0.87%
Full GNOM fund page

Invesco Nasdaq Biotechnology ETF (IBBQ) belongs to the US Health Care segment. Global X Genomics & Biotechnology ETF - USD (GNOM) is part of the BioTech & Genomics segment. IBBQ's top 3 sector exposures are Health Care and Consumer Staples. In contrast, GNOM's top sector exposures are Health Care  IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.5% for GNOM. IBBQ is up 0.75% year-to-date (YTD) with +$8M in YTD flows. GNOM performs worse with -4.2% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of IBBQ and GNOM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IBBQ vs GNOM performance and flow charts

Performance

-4.0-2.00.02.04.06.0%Feb 12Feb 20Feb 27Mar 6

Cumulative Flows

Feb 12Feb 20Feb 27Mar 6

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Historic performance and flows
Data as of 03/12/2026
1M3MYTD1Y3Y5Y
Perf.
IBBQ
GNOM
-1.87%-4.14%
+0.72%-5.72%
+0.75%-4.20%
+29.85%+23.30%
+46.86%-9.06%
n/a-52.80%
Flows
IBBQ
GNOM
--
+$12M-$4M
+$8M-$2M
+$21M-$19M
+$41M-$115M
-+$11M
Volatility and drawdown
3M1Y3Y5Y
Volatility
IBBQ
GNOM
+20.65%+24.30%
+23.15%+30.21%
+19.30%+28.57%
n/a+33.50%
Max drawdown
IBBQ
GNOM
-5.19%-13.77%
-17.24%-22.14%
-23.78%-46.50%
n/a-72.17%
Max drawdown duration
IBBQ
GNOM
16d49d
127d113d
375d1032d
n/a1715d
Trading data

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IBBQ
GNOM
Last sale
3/13/2026 at 1:30 PM
$28.46
$43.24
Previous close
03/12/2026
$28.59
$43.61
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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IBBQ
GNOM
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
IBBQ
GNOM
Last price
$28.46
$43.24
1D performance
-0.46%
-0.84%
AuM$72.05 M$47.76 M
E/R0.19%0.5%
Characteristics
IBBQ
GNOM
Management strategyPassivePassive
ProviderInvescoGlobal X
BenchmarkNASDAQ Biotechnology IndexSolactive Genomics Index
N° of holdings19646
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateJune 9, 2021April 5, 2019
ESGNoNo
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Exposure

Countries

IBBQ
USA
93.84%
Other
6.16%
GNOM
USA
87.04%
Other
12.96%

Sectors

IBBQ
Health Care
85.82%
Other
14.18%
GNOM
Health Care
87.95%
Other
12.05%
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Diversification

IBBQ

Total weight of top 15 holdings out of 15

52.08%
GNOM

Total weight of top 15 holdings out of 15

63.95%

Top 15 holdings

Data as of January 31, 2026
IBBQ
VERTEX PHARMACEUTICALS
8.96%
GILEAD SCIENCES
8.92%
AMGEN-T
8.25%
REGENERON PHARMACEUTICALS
5.90%
ALNYLAM PHARMACEUTICALS
3.58%
INSMED
2.55%
BIOGEN INC
1.90%
US04016X1019
1.82%
ILLUMINA
1.75%
UTD THERAPEUT
1.53%
INCYTE
1.51%
REVOLUTION MEDICINES INC
1.42%
MODERNA INC
1.41%
ROYALTY PHARMA
1.30%
MEDPACE HOLDINGS INC
1.27%
GNOM
MODERNA INC
6.79%
ARROWHEAD PHARMACEUTICALS INC
6.14%
US74006W2070
5.75%
ILLUMINA
5.64%
GUARDANT HEALTH INC
5.47%
NATERA
4.30%
VERTEX PHARMACEUTICALS
4.08%
BIONTECH SE ADR
4.04%
BIOMARIN PHARMACEUTICAL
3.93%
AVIDITY BIOSCIENCES
3.73%
BIO-TECHNE CORP
3.69%
CRISPR THERAPEUTICS
3.05%
ALNYLAM PHARMACEUTICALS
2.58%
VERACYTE INC/D
2.50%
BRISTOL-MYERS SQUIBB
2.28%
Frequently asked questions about IBBQ and GNOM

How have the IBBQ and GNOM ETFs performed in 2026?

As of March 12, 2026, IBBQ is up 0.75% year-to-date (YTD), while GNOM has lost -4.2%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or GNOM?

Year-to-date, the IBBQ ETF saw +$8M in flows, compared to -$2M for GNOM.

Which ETF is more volatile: IBBQ or GNOM?

Over the past year, IBBQ had a volatility of 23.15%, while GNOM experienced 30.21%.

Which ETF is bigger: IBBQ or GNOM?

As of March 12, 2026, IBBQ holds $72.05 M in assets under management (AUM), while GNOM manages $47.76 M.

What sectors do the IBBQ and GNOM ETFs invest in?

IBBQ leans toward sectors like Health Care. Meanwhile, GNOM focuses on Health Care.

What are the top holdings of the IBBQ ETF and GNOM ETF?

IBBQ top holdings include VERTEX PHARMACEUTICALS, GILEAD SCIENCES and AMGEN-T. GNOM holds in its top three: MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070.

Which ETF is more diversified: IBBQ or GNOM?

IBBQ holds 262 securities with 52.08% of its assets in the top 15. GNOM has 48 securities and a top 15 weight of 63.95%.

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