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IBBQvsFBTETF Comparison

ETF 1

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

+1.21%

Full IBBQ fund page

VS

ETF 2

FBT

First Trust NYSE Arca Biotechnology Index Fund ETF

This fund is part of

US Health Care

+1.21%

Full FBT fund page

Invesco Nasdaq Biotechnology ETF (IBBQ) and First Trust NYSE Arca Biotechnology Index Fund ETF (FBT) belong to the same industry segment: US Health Care. IBBQ's top 2 sector exposures are Healthcare and Non-Energy Materials. In contrast, FBT's top sector exposures are Healthcare. IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.54% for FBT. IBBQ is up 22.79% year-to-date (YTD) with +$19M in YTD flows. FBT performs better with 27.12% YTD performance, and +$964M in YTD flows. Run a side-by-side ETF comparison of IBBQ and FBT below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IBBQ vs FBT performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 09/14/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	IBBQ FBT	+2.85%+1.23%	+16.89%+15.15%	+22.79%+27.12%	+48.06%+46.31%	+74.15%+72.70%	+36.86%+54.37%
Flows	IBBQ FBT	+$13M+$13M	+$18M-$159M	+$19M+$964M	+$38M+$1.04B	+$54M+$626M	+$28M+$283M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	IBBQ FBT	+23.84%+22.04%	+21.54%+21.87%	+20.91%+21.09%	+22.08%+22.20%
Max drawdown	IBBQ FBT	-6.48%-4.50%	-8.38%-14.27%	-23.78%-19.92%	-37.23%-29.49%
Max drawdown duration	IBBQ FBT	26d15d	48d126d	375d237d	1485d1138d

Trading data

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	IBBQ	FBT
Last sale 9/15/2026 at 1:30 PM	$34.19	$263.04
Previous close 09/14/2026	$34.82	$264.26
Consolidated volume 09/14/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of August 31, 2026

1-year trailing difference

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	IBBQ	FBT
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 9/15/2026 at 1:30 PM

Live

Closed

	IBBQ	FBT
Last price	$34.19	$263.04
1D performance	-1.81%	-0.46%
AuM	$96.64 M	$2.85 B
E/R	0.19%	0.54%

Characteristics

	IBBQ	FBT
Management strategy	Passive	Passive
Provider	Invesco	First Trust
Benchmark	NASDAQ Biotechnology Index	NYSE Arca Biotechnology Index
N° of holdings	249	30
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 9, 2021	June 19, 2006
ESG	No	No

More IBBQ data on Trackinsight

More FBT data on Trackinsight

Exposure

Countries

IBBQ

USA

88.05%

Other

11.95%

FBT

USA

82.19%

Other

17.81%

Sectors

IBBQ

Healthcare

99.91%

Other

0.09%

FBT

Healthcare

99.86%

Other

0.14%

Diversification

IBBQ

Total weight of top 15 holdings out of 15

50.47%

FBT

Total weight of top 15 holdings out of 15

55.87%

Top 15 holdings

Data as of July 31, 2026

IBBQ

Amgen, Inc.

8.55%

Vertex Pharmaceuticals, Inc.

8.03%

Gilead Sciences, Inc.

7.34%

Regeneron Pharmaceuticals, Inc.

5.08%

Revolution Medicines, Inc.

2.73%

Alnylam Pharmaceuticals, Inc.

2.71%

Biogen, Inc.

2.19%

Illumina, Inc.

2.09%

Royalty Pharma Plc

1.86%

Incyte Corp.

1.80%

argenx SE

1.73%

Roivant Sciences Ltd.

1.68%

Insmed, Inc.

1.58%

United Therapeutics Corp.

1.58%

Moderna, Inc.

1.53%

FBT

Halozyme Therapeutics, Inc.

4.31%

Corcept Therapeutics, Inc.

4.08%

Repligen Corp.

3.87%

Regeneron Pharmaceuticals, Inc.

3.85%

BeOne Medicines Ltd.

3.83%

BioNTech SE

3.75%

Natera, Inc.

3.73%

Amgen, Inc.

3.70%

argenx SE

3.66%

NeoGenomics, Inc.

3.63%

Genmab A/S

3.57%

BioMarin Pharmaceutical, Inc.

3.55%

Illumina, Inc.

3.47%

Vertex Pharmaceuticals, Inc.

3.45%

Gilead Sciences, Inc.

3.42%

Frequently asked questions about IBBQ and FBT

How have the IBBQ and FBT ETFs performed in 2026?

As of September 14, 2026, IBBQ is up 22.79% year-to-date (YTD), while FBT has returned 27.12%. That puts FBT better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or FBT?

Year-to-date, the IBBQ ETF saw +$19M in flows, compared to +$964M for FBT.

Which ETF is more volatile: IBBQ or FBT?

Over the past year, IBBQ had a volatility of 21.54%, while FBT experienced 21.87%.

Which ETF is bigger: IBBQ or FBT?

As of September 14, 2026, IBBQ holds $96.64 M in assets under management (AUM), while FBT manages $2.85 B.

What sectors do the IBBQ and FBT ETFs invest in?

IBBQ leans toward sectors like Healthcare. Meanwhile, FBT focuses on Healthcare.

What are the top holdings of the IBBQ ETF and FBT ETF?

IBBQ top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. FBT holds in its top three: Halozyme Therapeutics, Inc., Corcept Therapeutics, Inc. and Repligen Corp..

Which ETF is more diversified: IBBQ or FBT?

IBBQ holds 249 securities with 50.47% of its assets in the top 15. FBT has 30 securities and a top 15 weight of 55.87%.

Biotech ETFs – Investing in Health Innovation

July 21, 2022

FBT

IBBQvsFBTETF Comparison

Invesco Nasdaq Biotechnology ETF

First Trust NYSE Arca Biotechnology Index Fund ETF

IBBQ vs FBT performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the IBBQ and FBT ETFs performed in 2026?

As of September 14, 2026, IBBQ is up 22.79% year-to-date (YTD), while FBT has returned 27.12%. That puts FBT better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or FBT?

Year-to-date, the IBBQ ETF saw +$19M in flows, compared to +$964M for FBT.

Which ETF is more volatile: IBBQ or FBT?

Over the past year, IBBQ had a volatility of 21.54%, while FBT experienced 21.87%.

Which ETF is bigger: IBBQ or FBT?

As of September 14, 2026, IBBQ holds $96.64 M in assets under management (AUM), while FBT manages $2.85 B.

What sectors do the IBBQ and FBT ETFs invest in?

IBBQ leans toward sectors like Healthcare. Meanwhile, FBT focuses on Healthcare.

What are the top holdings of the IBBQ ETF and FBT ETF?

IBBQ top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc.. FBT holds in its top three: Halozyme Therapeutics, Inc., Corcept Therapeutics, Inc. and Repligen Corp..

Which ETF is more diversified: IBBQ or FBT?

IBBQ holds 249 securities with 50.47% of its assets in the top 15. FBT has 30 securities and a top 15 weight of 55.87%.

Biotech ETFs – Investing in Health Innovation

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