BROUGHT TO YOU BY:

ETF Portfolio Builder

New

ETF Portfolio Builder

New

HTECvsPBEETF Comparison

ETF 1

HTEC

Robo Global Healthcare Technology and Innovation ETF

This fund is part of

Multiple Trends

-5.28%

Full HTEC fund page

VS

ETF 2

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

-5.05%

Full PBE fund page

Robo Global Healthcare Technology and Innovation ETF (HTEC) belongs to the Multiple Trends segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. HTEC's top 3 sector exposures are Healthcare, Consumer Non-Cyclicals and Business Services. In contrast, PBE's top sector exposures are Healthcare. HTEC is more expensive with a Total Expense Ratio (TER) of 0.8%, versus 0.59% for PBE. HTEC is up 28.41% year-to-date (YTD) with +$39M in YTD flows. PBE performs worse with 26.2% YTD performance, and +$109M in YTD flows. Run a side-by-side ETF comparison of HTEC and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

Find out how industry players manage ETF portfolios. Discover our library of Model portfolios

HTEC vs PBE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 10/30/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HTEC PBE	+2.89%+5.52%	+17.65%+12.47%	+28.41%+26.20%	+38.19%+42.26%	+108.35%+97.72%	-2.81%+36.83%
Flows	HTEC PBE	+$33M-$5M	+$22M+$106M	+$39M+$109M	+$39M+$111M	+$8M+$58M	-$70M+$61M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HTEC PBE	+23.55%+21.50%	+21.42%+20.03%	+20.98%+20.60%	+24.29%+22.66%
Max drawdown	HTEC PBE	-6.70%-5.97%	-16.84%-11.70%	-22.68%-22.21%	-54.51%-32.63%
Max drawdown duration	HTEC PBE	27d46d	160d166d	237d324d	1822d1468d

Trading data

Create an account to view trading data

Join for free

	HTEC	PBE
Last sale 10/30/2026 at 1:30 PM	$45.50	$102.50
Previous close 10/29/2026	$46.46	$103.46
Consolidated volume 10/29/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of October 30, 2026

1-year trailing difference

Create an account to view replication metrics

Join for free

Create an account to view replication quality

Join for free

	HTEC	PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 10/30/2026 at 1:30 PM

Live

Closed

	HTEC	PBE
Last price	$45.50	$102.50
1D performance	-2.06%	-0.93%
AuM	$112.65 M	$441.78 M
E/R	0.8%	0.59%

Characteristics

	HTEC	PBE
Management strategy	Passive	Passive
Provider	ROBO Global ETFs	Invesco
Benchmark	ROBO Global Healthcare Technology and Innovation	Dynamic Biotech & Genome Intellidex Index
N° of holdings	62	30
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 25, 2019	June 23, 2005
ESG	Yes	No

More HTEC data on Trackinsight

More PBE data on Trackinsight

Exposure

Countries

HTEC

USA

75.15%

Other

24.85%

PBE

USA

97.15%

Other

2.85%

Sectors

HTEC

Healthcare

94.15%

Other

5.85%

PBE

Healthcare

100%

Other

0%

Diversification

HTEC

Total weight of top 15 holdings out of 15

32.23%

PBE

Total weight of top 15 holdings out of 15

62.68%

Top 15 holdings

Data as of September 30, 2026

HTEC

Twist Bioscience Corp.

2.98%

GRAIL, Inc.

2.81%

Natera, Inc.

2.42%

Tempus AI, Inc.

2.34%

Illumina, Inc.

2.22%

Intuitive Surgical, Inc.

2.13%

Guardant Health, Inc.

2.12%

Thermo Fisher Scientific, Inc.

2.11%

Adaptive Biotechnologies Corp.

2.01%

Moderna, Inc.

1.91%

Medpace Holdings, Inc.

1.89%

CareDx, Inc.

1.86%

Vertex Pharmaceuticals, Inc.

1.84%

Danaher Corp.

1.80%

Siemens Healthineers AG

1.79%

PBE

Natera, Inc.

6.20%

Illumina, Inc.

6.13%

Biogen, Inc.

5.25%

Gilead Sciences, Inc.

5.19%

Vertex Pharmaceuticals, Inc.

4.84%

Amgen, Inc.

4.79%

Royalty Pharma Plc

4.77%

Regeneron Pharmaceuticals, Inc.

4.57%

Moderna, Inc.

3.43%

Novavax, Inc.

3.16%

Repligen Corp.

2.95%

Halozyme Therapeutics, Inc.

2.86%

QIAGEN NV

2.85%

Exelixis, Inc.

2.85%

Veracyte, Inc.

2.84%

Frequently asked questions about HTEC and PBE

How have the HTEC and PBE ETFs performed in 2026?

As of October 30, 2026, HTEC is up 28.41% year-to-date (YTD), while PBE has returned 26.2%. That puts HTEC better performer ahead so far this year.

Which ETF is attracting more investor money: HTEC or PBE?

Year-to-date, the HTEC ETF saw +$39M in flows, compared to +$109M for PBE.

Which ETF is more volatile: HTEC or PBE?

Over the past year, HTEC had a volatility of 21.42%, while PBE experienced 20.03%.

Which ETF is bigger: HTEC or PBE?

As of October 30, 2026, HTEC holds $112.65 M in assets under management (AUM), while PBE manages $441.78 M.

What sectors do the HTEC and PBE ETFs invest in?

HTEC leans toward sectors like Healthcare. Meanwhile, PBE focuses on Healthcare.

What are the top holdings of the HTEC ETF and PBE ETF?

HTEC top holdings include Twist Bioscience Corp., GRAIL, Inc. and Natera, Inc.. PBE holds in its top three: Natera, Inc., Illumina, Inc. and Biogen, Inc..

Which ETF is more diversified: HTEC or PBE?

HTEC holds 62 securities with 32.23% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 62.68%.

Biggest potential ETF theme - Innovation

October 13, 2022

HTEC

HTECvsPBEETF Comparison

Robo Global Healthcare Technology and Innovation ETF

Invesco Dynamic Biotechnology & Genome ETF

HTEC vs PBE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HTEC and PBE ETFs performed in 2026?

As of October 30, 2026, HTEC is up 28.41% year-to-date (YTD), while PBE has returned 26.2%. That puts HTEC better performer ahead so far this year.

Which ETF is attracting more investor money: HTEC or PBE?

Year-to-date, the HTEC ETF saw +$39M in flows, compared to +$109M for PBE.

Which ETF is more volatile: HTEC or PBE?

Over the past year, HTEC had a volatility of 21.42%, while PBE experienced 20.03%.

Which ETF is bigger: HTEC or PBE?

As of October 30, 2026, HTEC holds $112.65 M in assets under management (AUM), while PBE manages $441.78 M.

What sectors do the HTEC and PBE ETFs invest in?

HTEC leans toward sectors like Healthcare. Meanwhile, PBE focuses on Healthcare.

What are the top holdings of the HTEC ETF and PBE ETF?

HTEC top holdings include Twist Bioscience Corp., GRAIL, Inc. and Natera, Inc.. PBE holds in its top three: Natera, Inc., Illumina, Inc. and Biogen, Inc..

Which ETF is more diversified: HTEC or PBE?

HTEC holds 62 securities with 32.23% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 62.68%.

Biggest potential ETF theme - Innovation

ETFs’ Next Act: From Access to Selection