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HELXvsTMEDETF Comparison

ETF 1

HELX

Franklin Genomic Advancements ETF

This fund is part of

BioTech & Genomics

+0.42%

Full HELX fund page

VS

ETF 2

TMED

T. Rowe Price Health Care ETF

This fund is part of

US Health Care

+1.9%

Full TMED fund page

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. T. Rowe Price Health Care ETF (TMED) is part of the US Health Care segment. HELX's top 3 sector exposures are Healthcare, Non-Energy Materials and Technology. In contrast, TMED's top sector exposures are Healthcare, Consumer Non-Cyclicals and Non-Corporate. HELX is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.44% for TMED. HELX is up 26.78% year-to-date (YTD) with +$8M in YTD flows. TMED performs worse with 17.35% YTD performance, and +$17M in YTD flows. Run a side-by-side ETF comparison of HELX and TMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs TMED performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 10/29/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HELX TMED	+3.65%+1.76%	+18.42%-0.44%	+26.78%+17.35%	+34.48%+21.46%	+81.47%n/a	-13.69%n/a
Flows	HELX TMED	+$2M+$3M	+$2M+$10M	+$8M+$17M	+$8M+$18M	+$17M-	+$8M-

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HELX TMED	+27.48%+19.22%	+24.10%+18.73%	+21.93%n/a	+23.67%n/a
Max drawdown	HELX TMED	-8.93%-10.10%	-17.89%-11.09%	-29.16%n/a	-55.27%n/a
Max drawdown duration	HELX TMED	22d70d	206d125d	458dn/a	1822dn/a

Trading data

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	HELX	TMED
Last sale 10/30/2026 at 1:30 PM	$45.25	$34.34
Previous close 10/29/2026	$46.01	$34.82
Consolidated volume 10/29/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Main metrics

Last update 10/30/2026 at 1:30 PM

Live

Closed

	HELX	TMED
Last price	$45.25	$34.34
1D performance	-1.65%	-1.40%
AuM	$36.80 M	$36.57 M
E/R	0.5%	0.44%

Characteristics

	HELX	TMED
Management strategy	Active	Active
Provider	Franklin Templeton	T. Rowe Price
Benchmark	-	-
N° of holdings	66	110
Asset class	-	-
Trailing 12m distribution yield	Join	Join
Inception date	February 25, 2020	June 11, 2025
ESG	No	No

More HELX data on Trackinsight

More TMED data on Trackinsight

Exposure

Countries

HELX

USA

90.13%

Other

9.87%

TMED

USA

92.23%

Other

7.77%

Sectors

HELX

Healthcare

97.01%

Other

2.99%

TMED

Healthcare

98.03%

Other

1.97%

Diversification

HELX

Total weight of top 15 holdings out of 15

61.42%

TMED

Total weight of top 15 holdings out of 15

50.66%

Top 15 holdings

Data as of September 30, 2026

HELX

Natera, Inc.

10.25%

Guardant Health, Inc.

9.72%

Krystal Biotech, Inc.

5.32%

Twist Bioscience Corp.

5.01%

Adaptive Biotechnologies Corp.

4.95%

Ligand Pharmaceuticals, Inc.

4.33%

BridgeBio Pharma, Inc.

2.79%

Travere Therapeutics, Inc.

2.72%

Medpace Holdings, Inc.

2.64%

Vertex Pharmaceuticals, Inc.

2.62%

Corteva, Inc.

2.33%

Eli Lilly & Co.

2.25%

Tempus AI, Inc.

2.25%

United Therapeutics Corp.

2.20%

Repligen Corp.

2.04%

TMED

Eli Lilly & Co.

6.09%

Alnylam Pharmaceuticals, Inc.

5.67%

UnitedHealth Group, Inc.

5.21%

Thermo Fisher Scientific, Inc.

3.79%

Cencora, Inc.

3.40%

Insulet Corp.

3.25%

Gilead Sciences, Inc.

3.15%

Agilent Technologies, Inc.

3.01%

Intuitive Surgical, Inc.

2.80%

Elanco Animal Health, Inc.

2.72%

West Pharmaceutical Services, Inc.

2.49%

Cytokinetics, Inc.

2.40%

Danaher Corp.

2.36%

Waters Corp.

2.34%

Ascendis Pharma A/S

1.99%

Frequently asked questions about HELX and TMED

How have the HELX and TMED ETFs performed in 2026?

As of October 29, 2026, HELX is up 26.78% year-to-date (YTD), while TMED has returned 17.35%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or TMED?

Year-to-date, the HELX ETF saw +$8M in flows, compared to +$17M for TMED.

Which ETF is more volatile: HELX or TMED?

Over the past year, HELX had a volatility of 24.1%, while TMED experienced 18.73%.

Which ETF is bigger: HELX or TMED?

As of October 29, 2026, HELX holds $36.80 M in assets under management (AUM), while TMED manages $36.57 M.

What sectors do the HELX and TMED ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, TMED focuses on Healthcare.

What are the top holdings of the HELX ETF and TMED ETF?

HELX top holdings include Natera, Inc., Guardant Health, Inc. and Krystal Biotech, Inc.. TMED holds in its top three: Eli Lilly & Co., Alnylam Pharmaceuticals, Inc. and UnitedHealth Group, Inc..

HELXvsTMEDETF Comparison

Franklin Genomic Advancements ETF

T. Rowe Price Health Care ETF

HELX vs TMED performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HELX and TMED ETFs performed in 2026?

As of October 29, 2026, HELX is up 26.78% year-to-date (YTD), while TMED has returned 17.35%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or TMED?

Year-to-date, the HELX ETF saw +$8M in flows, compared to +$17M for TMED.

Which ETF is more volatile: HELX or TMED?

Over the past year, HELX had a volatility of 24.1%, while TMED experienced 18.73%.

Which ETF is bigger: HELX or TMED?

As of October 29, 2026, HELX holds $36.80 M in assets under management (AUM), while TMED manages $36.57 M.

What sectors do the HELX and TMED ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, TMED focuses on Healthcare.

What are the top holdings of the HELX ETF and TMED ETF?

HELX top holdings include Natera, Inc., Guardant Health, Inc. and Krystal Biotech, Inc.. TMED holds in its top three: Eli Lilly & Co., Alnylam Pharmaceuticals, Inc. and UnitedHealth Group, Inc..

Which ETF is more diversified: HELX or TMED?

HELX holds 66 securities with 61.42% of its assets in the top 15. TMED has 112 securities and a top 15 weight of 50.66%.

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