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HELXvsPTHETF Comparison

ETF 1

HELX

Franklin Genomic Advancements ETF

This fund is part of

BioTech & Genomics

-5.05%

Full HELX fund page

VS

ETF 2

PTH

Invesco DWA Healthcare Momentum ETF

This fund is part of

US Health Care

+0.03%

Full PTH fund page

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. Invesco DWA Healthcare Momentum ETF (PTH) is part of the US Health Care segment. HELX's top 3 sector exposures are Healthcare, Non-Energy Materials and Technology. In contrast, PTH's top sector exposures are Healthcare and Consumer Non-Cyclicals. HELX is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.72% for PTH. HELX is up 24.75% year-to-date (YTD) with +$8M in YTD flows. PTH performs worse with 20.14% YTD performance, and +$149M in YTD flows. Run a side-by-side ETF comparison of HELX and PTH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs PTH performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 10/30/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HELX PTH	+1.74%-1.69%	+14.13%+0.82%	+24.75%+20.14%	+30.17%+27.98%	+78.56%+107.64%	-15.82%+11.90%
Flows	HELX PTH	+$2M-$67M	+$2M+$56M	+$8M+$149M	+$8M+$158M	+$17M+$102M	+$8M-$105M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HELX PTH	+27.48%+28.86%	+24.12%+27.09%	+21.94%+26.08%	+23.68%+25.94%
Max drawdown	HELX PTH	-8.93%-12.72%	-17.89%-12.72%	-29.16%-27.71%	-55.27%-47.24%
Max drawdown duration	HELX PTH	22d72d	206d72d	458d353d	1823d1688d

Trading data

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	HELX	PTH
Last sale 10/30/2026 at 1:30 PM	$45.25	$59.78
Previous close 10/29/2026	$46.01	$61.26
Consolidated volume 10/29/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of September 30, 2026

1-year trailing difference

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HELX

is actively managed and doesn’t replicate an index

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	HELX	PTH
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 10/30/2026 at 1:30 PM

Live

Closed

	HELX	PTH
Last price	$45.25	$59.78
1D performance	-1.65%	-2.42%
AuM	$36.21 M	$295.06 M
E/R	0.5%	0.72%

Characteristics

	HELX	PTH
Management strategy	Active	Passive
Provider	Franklin Templeton	Invesco
Benchmark	-	Dorsey Wright Healthcare Technical Leaders Index
N° of holdings	66	54
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	February 25, 2020	October 12, 2006
ESG	No	No

More HELX data on Trackinsight

More PTH data on Trackinsight

Exposure

Countries

HELX

USA

90.13%

Other

9.87%

PTH

USA

90.51%

Other

9.49%

Sectors

HELX

Healthcare

97.01%

Other

2.99%

PTH

Healthcare

99.23%

Other

0.77%

Diversification

HELX

Total weight of top 15 holdings out of 15

61.42%

PTH

Total weight of top 15 holdings out of 15

51.15%

Top 15 holdings

Data as of September 30, 2026

HELX

Natera, Inc.

10.25%

Guardant Health, Inc.

9.72%

Krystal Biotech, Inc.

5.32%

Twist Bioscience Corp.

5.01%

Adaptive Biotechnologies Corp.

4.95%

Ligand Pharmaceuticals, Inc.

4.33%

BridgeBio Pharma, Inc.

2.79%

Travere Therapeutics, Inc.

2.72%

Medpace Holdings, Inc.

2.64%

Vertex Pharmaceuticals, Inc.

2.62%

Corteva, Inc.

2.33%

Eli Lilly & Co.

2.25%

Tempus AI, Inc.

2.25%

United Therapeutics Corp.

2.20%

Repligen Corp.

2.04%

PTH

Moderna, Inc.

6.40%

Guardant Health, Inc.

5.11%

Roivant Sciences Ltd.

5.06%

Revolution Medicines, Inc.

4.98%

10X Genomics, Inc.

3.99%

BrightSpring Health Services, Inc.

3.58%

Axsome Therapeutics, Inc.

3.44%

Twist Bioscience Corp.

2.92%

Illumina, Inc.

2.59%

Liquidia Corp.

2.47%

Oruka Therapeutics, Inc.

2.23%

Travere Therapeutics, Inc.

2.23%

Erasca, Inc.

2.15%

Replimune Group, Inc.

2.03%

Axogen, Inc.

1.98%

Frequently asked questions about HELX and PTH

How have the HELX and PTH ETFs performed in 2026?

As of October 30, 2026, HELX is up 24.75% year-to-date (YTD), while PTH has returned 20.14%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or PTH?

Year-to-date, the HELX ETF saw +$8M in flows, compared to +$149M for PTH.

Which ETF is more volatile: HELX or PTH?

Over the past year, HELX had a volatility of 24.12%, while PTH experienced 27.09%.

Which ETF is bigger: HELX or PTH?

As of October 30, 2026, HELX holds $36.21 M in assets under management (AUM), while PTH manages $295.06 M.

What sectors do the HELX and PTH ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, PTH focuses on Healthcare.

What are the top holdings of the HELX ETF and PTH ETF?

HELX top holdings include Natera, Inc., Guardant Health, Inc. and Krystal Biotech, Inc.. PTH holds in its top three: Moderna, Inc., Guardant Health, Inc. and Roivant Sciences Ltd..

Which ETF is more diversified: HELX or PTH?

HELX holds 66 securities with 61.42% of its assets in the top 15. PTH has 54 securities and a top 15 weight of 51.15%.

Continued tightening of the U.S. labor market

September 23, 2022

PTH

HELXvsPTHETF Comparison

Franklin Genomic Advancements ETF

Invesco DWA Healthcare Momentum ETF

HELX vs PTH performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HELX and PTH ETFs performed in 2026?

As of October 30, 2026, HELX is up 24.75% year-to-date (YTD), while PTH has returned 20.14%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or PTH?

Year-to-date, the HELX ETF saw +$8M in flows, compared to +$149M for PTH.

Which ETF is more volatile: HELX or PTH?

Over the past year, HELX had a volatility of 24.12%, while PTH experienced 27.09%.

Which ETF is bigger: HELX or PTH?

As of October 30, 2026, HELX holds $36.21 M in assets under management (AUM), while PTH manages $295.06 M.

What sectors do the HELX and PTH ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, PTH focuses on Healthcare.

What are the top holdings of the HELX ETF and PTH ETF?

HELX top holdings include Natera, Inc., Guardant Health, Inc. and Krystal Biotech, Inc.. PTH holds in its top three: Moderna, Inc., Guardant Health, Inc. and Roivant Sciences Ltd..

Which ETF is more diversified: HELX or PTH?

HELX holds 66 securities with 61.42% of its assets in the top 15. PTH has 54 securities and a top 15 weight of 51.15%.

Continued tightening of the U.S. labor market

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