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HELXvsPTHETF Comparison

ETF 1

HELX

Franklin Genomic Advancements ETF

This fund is part of

BioTech & Genomics

+0.29%

Full HELX fund page

VS

ETF 2

PTH

Invesco DWA Healthcare Momentum ETF

This fund is part of

US Health Care

-0.12%

Full PTH fund page

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. Invesco DWA Healthcare Momentum ETF (PTH) is part of the US Health Care segment. HELX's top 3 sector exposures are Healthcare, Non-Energy Materials and Technology. In contrast, PTH's top sector exposures are Healthcare and Consumer Non-Cyclicals. HELX is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.72% for PTH. HELX is up 12.93% year-to-date (YTD) with +$6M in YTD flows. PTH performs better with 22.21% YTD performance, and +$131M in YTD flows. Run a side-by-side ETF comparison of HELX and PTH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs PTH performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 09/11/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HELX PTH	-1.05%+1.34%	+15.09%+20.02%	+12.93%+22.21%	+33.15%+52.93%	+37.37%+70.20%	-26.59%+11.54%
Flows	HELX PTH	-+$25M	+$4M+$142M	+$6M+$131M	+$8M+$138M	+$15M+$78M	+$4M-$153M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HELX PTH	+24.44%+27.88%	+22.84%+26.02%	+21.42%+25.99%	+23.54%+25.74%
Max drawdown	HELX PTH	-6.59%-7.42%	-17.89%-11.91%	-29.16%-27.71%	-58.16%-49.87%
Max drawdown duration	HELX PTH	28d40d	206d140d	458d353d	1814d1735d

Trading data

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	HELX	PTH
Last sale 9/14/2026 at 1:30 PM	$41.56	$61.75
Previous close 09/11/2026	$40.99	$60.77
Consolidated volume 09/11/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of August 31, 2026

1-year trailing difference

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HELX

is actively managed and doesn’t replicate an index

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	HELX	PTH
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 9/14/2026 at 1:30 PM

Live

Closed

	HELX	PTH
Last price	$41.56	$61.75
1D performance	+1.40%	+1.61%
AuM	$30.73 M	$283.73 M
E/R	0.5%	0.72%

Characteristics

	HELX	PTH
Management strategy	Active	Passive
Provider	Franklin Templeton	Invesco
Benchmark	-	Dorsey Wright Healthcare Technical Leaders Index
N° of holdings	66	54
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	February 25, 2020	October 12, 2006
ESG	No	No

More HELX data on Trackinsight

More PTH data on Trackinsight

Exposure

Countries

HELX

USA

86.99%

Other

13.01%

PTH

USA

89.98%

Other

10.02%

Sectors

HELX

Healthcare

96.35%

Other

3.65%

PTH

Healthcare

99.16%

Other

0.84%

Diversification

HELX

Total weight of top 15 holdings out of 15

60.19%

PTH

Total weight of top 15 holdings out of 15

47.09%

Top 15 holdings

Data as of July 31, 2026

HELX

Guardant Health, Inc.

9.10%

Natera, Inc.

7.31%

Krystal Biotech, Inc.

6.17%

Ligand Pharmaceuticals, Inc.

4.48%

Adaptive Biotechnologies Corp.

4.33%

BridgeBio Pharma, Inc.

4.08%

United Therapeutics Corp.

3.52%

Eli Lilly & Co.

3.04%

Vertex Pharmaceuticals, Inc.

2.73%

SAMSUNG BIOLOGICS Co., Ltd.

2.72%

Travere Therapeutics, Inc.

2.67%

Corteva, Inc.

2.65%

AstraZeneca PLC

2.49%

Twist Bioscience Corp.

2.47%

Medpace Holdings, Inc.

2.44%

PTH

Roivant Sciences Ltd.

4.88%

Revolution Medicines, Inc.

4.85%

BrightSpring Health Services, Inc.

4.77%

Guardant Health, Inc.

4.50%

Axsome Therapeutics, Inc.

4.38%

Liquidia Corp.

3.17%

Erasca, Inc.

2.92%

Oruka Therapeutics, Inc.

2.54%

10X Genomics, Inc.

2.27%

Relay Therapeutics, Inc.

2.23%

Travere Therapeutics, Inc.

2.18%

Agilon Health, Inc.

2.13%

Oscar Health, Inc.

2.09%

Arrowhead Pharmaceuticals, Inc.

2.09%

Tango Therapeutics, Inc.

2.09%

Frequently asked questions about HELX and PTH

How have the HELX and PTH ETFs performed in 2026?

As of September 11, 2026, HELX is up 12.93% year-to-date (YTD), while PTH has returned 22.21%. That puts PTH better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or PTH?

Year-to-date, the HELX ETF saw +$6M in flows, compared to +$131M for PTH.

Which ETF is more volatile: HELX or PTH?

Over the past year, HELX had a volatility of 22.84%, while PTH experienced 26.02%.

Which ETF is bigger: HELX or PTH?

As of September 11, 2026, HELX holds $30.73 M in assets under management (AUM), while PTH manages $283.73 M.

What sectors do the HELX and PTH ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, PTH focuses on Healthcare.

What are the top holdings of the HELX ETF and PTH ETF?

HELX top holdings include Guardant Health, Inc., Natera, Inc. and Krystal Biotech, Inc.. PTH holds in its top three: Roivant Sciences Ltd., Revolution Medicines, Inc. and BrightSpring Health Services, Inc..

Which ETF is more diversified: HELX or PTH?

HELX holds 66 securities with 60.19% of its assets in the top 15. PTH has 54 securities and a top 15 weight of 47.09%.

Continued tightening of the U.S. labor market

September 23, 2022

PTH

HELXvsPTHETF Comparison

Franklin Genomic Advancements ETF

Invesco DWA Healthcare Momentum ETF

HELX vs PTH performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HELX and PTH ETFs performed in 2026?

As of September 11, 2026, HELX is up 12.93% year-to-date (YTD), while PTH has returned 22.21%. That puts PTH better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or PTH?

Year-to-date, the HELX ETF saw +$6M in flows, compared to +$131M for PTH.

Which ETF is more volatile: HELX or PTH?

Over the past year, HELX had a volatility of 22.84%, while PTH experienced 26.02%.

Which ETF is bigger: HELX or PTH?

As of September 11, 2026, HELX holds $30.73 M in assets under management (AUM), while PTH manages $283.73 M.

What sectors do the HELX and PTH ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, PTH focuses on Healthcare.

What are the top holdings of the HELX ETF and PTH ETF?

HELX top holdings include Guardant Health, Inc., Natera, Inc. and Krystal Biotech, Inc.. PTH holds in its top three: Roivant Sciences Ltd., Revolution Medicines, Inc. and BrightSpring Health Services, Inc..

Which ETF is more diversified: HELX or PTH?

HELX holds 66 securities with 60.19% of its assets in the top 15. PTH has 54 securities and a top 15 weight of 47.09%.

Continued tightening of the U.S. labor market

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