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HELXvsIBBQETF Comparison

ETF 1

HELX

Franklin Genomic Advancements ETF

This fund is part of

BioTech & Genomics

-0.67%

Full HELX fund page

VS

ETF 2

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

-1.08%

Full IBBQ fund page

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. HELX's top 3 sector exposures are Health Care, Materials and Information Technology. In contrast, IBBQ's top sector exposures are Health Care, Consumer Staples HELX is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.19% for IBBQ. HELX is down -7.69% year-to-date (YTD) with +$2M in YTD flows. IBBQ performs better with 3.49% YTD performance, and +$290K in YTD flows. Run a side-by-side ETF comparison of HELX and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs IBBQ performance and flow charts

Performance

Cumulative Flows

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Data Services

Historic performance and flows

Data as of 04/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HELX IBBQ	+5.41%+5.67%	-10.90%-0.91%	-7.69%+3.49%	+23.56%+41.67%	+9.47%+41.72%	-30.03%n/a
Flows	HELX IBBQ	--$8M	--$9M	+$2M+$290K	+$8M+$14M	+$9M+$34M	+$14M-

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HELX IBBQ	+24.83%+22.23%	+20.80%+21.05%	+20.28%+19.62%	+23.68%n/a
Max drawdown	HELX IBBQ	-16.86%-8.38%	-17.89%-8.39%	-29.16%-23.78%	-58.50%n/a
Max drawdown duration	HELX IBBQ	88d48d	145d33d	458d375d	1690dn/a

Trading data

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	HELX	IBBQ
Last sale 4/24/2026 at 7:59 PM	$33.52	$29.33
Previous close 04/24/2026	$33.42	$29.34
Consolidated volume 04/24/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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HELX

is actively managed and doesn’t replicate an index

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	HELX	IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/24/2026 at 7:59 PM

Live

Closed

	HELX	IBBQ
Last price	$33.52	$29.33
1D performance	+0.32%	-0.02%
AuM	$21.77 M	$66.29 M
E/R	0.5%	0.19%

Characteristics

	HELX	IBBQ
Management strategy	Active	Passive
Provider	Franklin Templeton	Invesco
Benchmark	-	NASDAQ Biotechnology Index
N° of holdings	51	192
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	February 25, 2020	June 9, 2021
ESG	No	No

More HELX data on Trackinsight

More IBBQ data on Trackinsight

Exposure

Countries

HELX

USA

87.6%

Other

12.4%

IBBQ

USA

92.77%

Other

7.23%

Sectors

HELX

Health Care

89.74%

Other

10.26%

IBBQ

Health Care

85.9%

Other

14.1%

Diversification

HELX

Total weight of top 15 holdings out of 15

60.42%

IBBQ

Total weight of top 15 holdings out of 15

51.37%

Top 15 holdings

Data as of March 31, 2026

HELX

NATERA

6.89%

GUARDANT HEALTH INC

6.82%

KRYSTAL BIOTECH INC

5.46%

UTD THERAPEUT

4.40%

BRIDGEBIO PHARMA

4.36%

INSMED

4.31%

LIGAND PHARMACEUTICALS

3.80%

SAMSUNG BIOLOGICS CO LTD

3.37%

ADAPTIVE BIOTECHNOLOGIES

3.32%

ASTRAZENECA

3.24%

VERTEX PHARMACEUTICALS

3.20%

MEDPACE HOLDINGS INC

3.05%

CORTEVA INC

2.81%

ALNYLAM PHARMACEUTICALS

2.71%

REGENERON PHARMACEUTICALS

2.67%

IBBQ

GILEAD SCIENCES

7.85%

AMGEN-T

7.82%

VERTEX PHARMACEUTICALS

7.59%

REGENERON PHARMACEUTICALS

6.48%

ALNYLAM PHARMACEUTICALS

3.56%

INSMED

2.65%

BIOGEN INC

2.28%

UTD THERAPEUT

1.94%

ROYALTY PHARMA

1.68%

US04016X1019

1.66%

MODERNA INC

1.66%

ROIVANT SCIENCES LTD

1.61%

REVOLUTION MEDICINES INC

1.55%

ILLUMINA

1.52%

INCYTE

1.52%

Frequently asked questions about HELX and IBBQ

How have the HELX and IBBQ ETFs performed in 2026?

As of April 24, 2026, HELX is down -7.69% year-to-date (YTD), while IBBQ has returned 3.49%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or IBBQ?

Year-to-date, the HELX ETF saw +$2M in flows, compared to +$290K for IBBQ.

Which ETF is more volatile: HELX or IBBQ?

Over the past year, HELX had a volatility of 20.8%, while IBBQ experienced 21.05%.

Which ETF is bigger: HELX or IBBQ?

As of April 24, 2026, HELX holds $21.77 M in assets under management (AUM), while IBBQ manages $66.29 M.

What sectors do the HELX and IBBQ ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the HELX ETF and IBBQ ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. IBBQ holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.

HELXvsIBBQETF Comparison

Franklin Genomic Advancements ETF

Invesco Nasdaq Biotechnology ETF

HELX vs IBBQ performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HELX and IBBQ ETFs performed in 2026?

As of April 24, 2026, HELX is down -7.69% year-to-date (YTD), while IBBQ has returned 3.49%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or IBBQ?

Year-to-date, the HELX ETF saw +$2M in flows, compared to +$290K for IBBQ.

Which ETF is more volatile: HELX or IBBQ?

Over the past year, HELX had a volatility of 20.8%, while IBBQ experienced 21.05%.

Which ETF is bigger: HELX or IBBQ?

As of April 24, 2026, HELX holds $21.77 M in assets under management (AUM), while IBBQ manages $66.29 M.

What sectors do the HELX and IBBQ ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the HELX ETF and IBBQ ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. IBBQ holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.

Which ETF is more diversified: HELX or IBBQ?

HELX holds 60 securities with 60.42% of its assets in the top 15. IBBQ has 256 securities and a top 15 weight of 51.37%.

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