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HELXvsHEALETF Comparison

ETF 1
HELX

Franklin Genomic Advancements ETF

This fund is part of
BioTech & Genomics
-0.67%
VS
ETF 2
HEAL

Global X HealthTech ETF - USD

This fund is part of
Healthcare Technology
-0.51%

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. Global X HealthTech ETF - USD (HEAL) is part of the Healthcare Technology segment. HELX's top 3 sector exposures are Health Care, Materials and Information Technology. In contrast, HEAL's top sector exposures are Health Care, Consumer Discretionary and Financials. Both HELX and HEAL have the same Total Expense Ratio (TER) of 0.5%. HELX is down -7.69% year-to-date (YTD) with +$2M in YTD flows. HEAL performs worse with -12.57% YTD performance, and -$11M in YTD flows. Run a side-by-side ETF comparison of HELX and HEAL below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs HEAL performance and flow charts

Performance

-50510%Mar 24Mar 31Apr 8Apr 15Apr 22

Cumulative Flows

-2 M-1.5 M-1 M-0.5 M0 MMar 24Mar 31Apr 8Apr 15Apr 22

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 04/24/2026
1M3MYTD1Y3Y5Y
Perf.
HELX
HEAL
+5.41%+4.99%
-10.90%-14.80%
-7.69%-12.57%
+23.56%-9.06%
+9.47%-29.13%
-30.03%-57.70%
Flows
HELX
HEAL
--$2M
--$8M
+$2M-$11M
+$8M-$4M
+$9M-$74M
+$14M-$556M
Volatility and drawdown
3M1Y3Y5Y
Volatility
HELX
HEAL
+24.83%+24.15%
+20.80%+21.57%
+20.28%+23.00%
+23.68%+25.19%
Max drawdown
HELX
HEAL
-16.86%-22.82%
-17.89%-30.39%
-29.16%-35.90%
-58.50%-61.68%
Max drawdown duration
HELX
HEAL
88d88d
145d198d
458d1012d
1690d1824d
Trading data

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HELX
HEAL
Last sale
4/24/2026 at 7:59 PM
$33.52
$25.72
Previous close
04/24/2026
$33.42
$25.52
Consolidated volume
04/24/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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HELX
is actively managed and doesn’t replicate an index

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HELX
HEAL
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/24/2026 at 7:59 PM
Live
Closed
HELX
HEAL
Last price
$33.52
$25.72
1D performance
+0.32%
+0.78%
AuM$21.77 M$25.60 M
E/R0.5%0.5%
Characteristics
HELX
HEAL
Management strategyActivePassive
ProviderFranklin TempletonGlobal X
Benchmark-Global X HealthTech Index
N° of holdings5135
Asset class--
Trailing 12m distribution yield
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Inception dateFebruary 25, 2020July 29, 2020
ESGNoNo
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Exposure

Countries

HELX
USA
87.6%
Other
12.4%
HEAL
USA
81.47%
Other
18.53%

Sectors

HELX
Health Care
89.74%
Other
10.26%
HEAL
Health Care
78.92%
Other
21.08%
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Diversification

HELX

Total weight of top 15 holdings out of 15

60.42%
HEAL

Total weight of top 15 holdings out of 15

63.46%

Top 15 holdings

Data as of March 31, 2026
HELX
NATERA
6.89%
GUARDANT HEALTH INC
6.82%
KRYSTAL BIOTECH INC
5.46%
UTD THERAPEUT
4.40%
BRIDGEBIO PHARMA
4.36%
INSMED
4.31%
LIGAND PHARMACEUTICALS
3.80%
SAMSUNG BIOLOGICS CO LTD
3.37%
ADAPTIVE BIOTECHNOLOGIES
3.32%
ASTRAZENECA
3.24%
VERTEX PHARMACEUTICALS
3.20%
MEDPACE HOLDINGS INC
3.05%
CORTEVA INC
2.81%
ALNYLAM PHARMACEUTICALS
2.71%
REGENERON PHARMACEUTICALS
2.67%
HEAL
MASIMO
6.46%
DEXCOM
5.87%
KONINKLIJKE PHILIPS NV
4.98%
US36266G1076
4.91%
RESMED
4.58%
ALIBABA HEALTH INFO TECHNOLOGY LTD
4.33%
INTUITIVE SURGICAL
4.19%
TRANSMEDICS GROUP
4.13%
IQVIA HOLDINGS INC
4.11%
ALIGNMENT HEALTHCARE
3.49%
IRHYTHM TECHNOLOGIES
3.42%
INSULET
3.39%
US9467841055
3.38%
VEEVA SYSTEMS IN
3.12%
US88023B1035
3.09%
Frequently asked questions about HELX and HEAL

How have the HELX and HEAL ETFs performed in 2026?

As of April 24, 2026, HELX is down -7.69% year-to-date (YTD), while HEAL has lost -12.57%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or HEAL?

Year-to-date, the HELX ETF saw +$2M in flows, compared to -$11M for HEAL.

Which ETF is more volatile: HELX or HEAL?

Over the past year, HELX had a volatility of 20.8%, while HEAL experienced 21.57%.

Which ETF is bigger: HELX or HEAL?

As of April 24, 2026, HELX holds $21.77 M in assets under management (AUM), while HEAL manages $25.60 M.

What sectors do the HELX and HEAL ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, HEAL focuses on Health Care.

What are the top holdings of the HELX ETF and HEAL ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. HEAL holds in its top three: MASIMO, DEXCOM and KONINKLIJKE PHILIPS NV.

Which ETF is more diversified: HELX or HEAL?

HELX holds 60 securities with 60.42% of its assets in the top 15. HEAL has 39 securities and a top 15 weight of 63.46%.

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