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HELXvsGNOMETF Comparison

ETF 1

HELX

Franklin Genomic Advancements ETF

This fund is part of

BioTech & Genomics

+0%

Full HELX fund page

VS

ETF 2

GNOM

Global X Genomics & Biotechnology ETF

This fund is part of

BioTech & Genomics

+0%

Full GNOM fund page

Franklin Genomic Advancements ETF (HELX) and Global X Genomics & Biotechnology ETF (GNOM) belong to the same industry segment: BioTech & Genomics. HELX's top 3 sector exposures are Health Care, Materials and Information Technology. In contrast, GNOM's top sector exposures are Health Care, Both HELX and GNOM have the same Total Expense Ratio (TER) of 0.5%. HELX is up 0.52% year-to-date (YTD) with +$2M in YTD flows. GNOM performs better with 14.12% YTD performance, and +$4M in YTD flows. Run a side-by-side ETF comparison of HELX and GNOM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs GNOM performance and flow charts

Performance

Cumulative Flows

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Data Services

Historic performance and flows

Data as of 06/18/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HELX GNOM	+12.21%+17.83%	+13.29%+20.65%	+0.52%+14.12%	+33.94%+59.76%	+19.15%+3.95%	-21.05%-42.05%
Flows	HELX GNOM	-+$4M	-+$6M	+$2M+$4M	+$8M-$4M	+$9M-$104M	+$14M+$2M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HELX GNOM	+26.26%+31.48%	+21.06%+26.67%	+20.61%+28.99%	+23.62%+33.29%
Max drawdown	HELX GNOM	-6.54%-7.88%	-17.89%-18.16%	-29.16%-44.85%	-58.50%-72.17%
Max drawdown duration	HELX GNOM	38d36d	200d145d	458d946d	1745d1813d

Trading data

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	HELX	GNOM
Last sale 6/18/2026 at 1:30 PM	$36.49	$52.07
Previous close 06/18/2026	$36.04	$51.30
Consolidated volume 06/18/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of May 29, 2026

1-year trailing difference

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HELX

is actively managed and doesn’t replicate an index

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	HELX	GNOM
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 6/18/2026 at 1:30 PM

Live

Closed

	HELX	GNOM
Last price	$36.49	$52.07
1D performance	+1.24%	+1.50%
AuM	$23.71 M	$63.13 M
E/R	0.5%	0.5%

Characteristics

	HELX	GNOM
Management strategy	Active	Passive
Provider	Franklin Templeton	Global X
Benchmark	-	Solactive Genomics Index
N° of holdings	50	45
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	February 25, 2020	April 5, 2019
ESG	No	No

More HELX data on Trackinsight

More GNOM data on Trackinsight

Exposure

Countries

HELX

USA

87.65%

Other

12.35%

GNOM

USA

88%

Other

12%

Sectors

HELX

Health Care

89.42%

Other

10.58%

GNOM

Health Care

88.52%

Other

11.48%

Diversification

HELX

Total weight of top 15 holdings out of 15

58.48%

GNOM

Total weight of top 15 holdings out of 15

66.44%

Top 15 holdings

Data as of April 30, 2026

HELX

NATERA

6.86%

GUARDANT HEALTH INC

6.56%

KRYSTAL BIOTECH INC

5.67%

UTD THERAPEUT

4.48%

LIGAND PHARMACEUTICALS

4.31%

BRIDGEBIO PHARMA

4.28%

INSMED

3.80%

ASTRAZENECA

3.26%

ADAPTIVE BIOTECHNOLOGIES

3.23%

SAMSUNG BIOLOGICS CO LTD

3.14%

VERTEX PHARMACEUTICALS

2.87%

REGENERON PHARMACEUTICALS

2.60%

CORTEVA INC

2.58%

ALNYLAM PHARMACEUTICALS

2.44%

LILLY

2.39%

GNOM

MODERNA INC

7.59%

ARROWHEAD PHARMACEUTICALS INC

7.18%

US74006W2070

6.77%

ILLUMINA

5.19%

GUARDANT HEALTH INC

4.73%

BIOMARIN PHARMACEUTICAL

4.29%

VERTEX PHARMACEUTICALS

4.16%

NATERA

4.14%

BIONTECH SE ADR

4.03%

BIO-TECHNE CORP

3.44%

CRISPR THERAPEUTICS

3.32%

TWIST BIOSCIENCE CORP

3.14%

LEGEND BIOTECH

2.91%

NL0015002SN0

2.77%

BRISTOL-MYERS SQUIBB

2.77%

Frequently asked questions about HELX and GNOM

How have the HELX and GNOM ETFs performed in 2026?

As of June 18, 2026, HELX is up 0.52% year-to-date (YTD), while GNOM has returned 14.12%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or GNOM?

Year-to-date, the HELX ETF saw +$2M in flows, compared to +$4M for GNOM.

Which ETF is more volatile: HELX or GNOM?

Over the past year, HELX had a volatility of 21.06%, while GNOM experienced 26.67%.

Which ETF is bigger: HELX or GNOM?

As of June 18, 2026, HELX holds $23.71 M in assets under management (AUM), while GNOM manages $63.13 M.

What sectors do the HELX and GNOM ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, GNOM focuses on Health Care.

What are the top holdings of the HELX ETF and GNOM ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. GNOM holds in its top three: MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070.

HELXvsGNOMETF Comparison

Franklin Genomic Advancements ETF

Global X Genomics & Biotechnology ETF

HELX vs GNOM performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HELX and GNOM ETFs performed in 2026?

As of June 18, 2026, HELX is up 0.52% year-to-date (YTD), while GNOM has returned 14.12%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or GNOM?

Year-to-date, the HELX ETF saw +$2M in flows, compared to +$4M for GNOM.

Which ETF is more volatile: HELX or GNOM?

Over the past year, HELX had a volatility of 21.06%, while GNOM experienced 26.67%.

Which ETF is bigger: HELX or GNOM?

As of June 18, 2026, HELX holds $23.71 M in assets under management (AUM), while GNOM manages $63.13 M.

What sectors do the HELX and GNOM ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, GNOM focuses on Health Care.

What are the top holdings of the HELX ETF and GNOM ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. GNOM holds in its top three: MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070.

Which ETF is more diversified: HELX or GNOM?

HELX holds 60 securities with 58.48% of its assets in the top 15. GNOM has 49 securities and a top 15 weight of 66.44%.

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