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HELXvsGNOMETF Comparison

ETF 1
HELX

Franklin Genomic Advancements ETF

This fund is part of
BioTech & Genomics
+0.29%
VS
ETF 2
GNOM

Global X Genomics & Biotechnology ETF

This fund is part of
BioTech & Genomics
+0.29%

Franklin Genomic Advancements ETF (HELX) and Global X Genomics & Biotechnology ETF (GNOM) belong to the same industry segment: BioTech & Genomics. HELX's top 3 sector exposures are Healthcare, Non-Energy Materials and Technology. Both HELX and GNOM have the same Total Expense Ratio (TER) of 0.5%. HELX is up 12.93% year-to-date (YTD) with +$6M in YTD flows. GNOM performs better with 36.95% YTD performance, and +$21M in YTD flows. Run a side-by-side ETF comparison of HELX and GNOM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs GNOM performance and flow charts

Performance

0510%Aug 11Aug 18Aug 25Sep 1Sep 9

Cumulative Flows

-3 M-2 M-1 M0 M1 M2 MAug 11Aug 18Aug 25Sep 1Sep 9

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 09/11/2026
1M3MYTD1Y3Y5Y
Perf.
HELX
GNOM
-1.05%+4.57%
+15.09%+27.28%
+12.93%+36.95%
+33.15%+69.95%
+37.37%+43.87%
-26.59%-32.85%
Flows
HELX
GNOM
-+$2M
+$4M+$18M
+$6M+$21M
+$8M+$15M
+$15M-$54M
+$4M-$42M
Volatility and drawdown
3M1Y3Y5Y
Volatility
HELX
GNOM
+24.44%+37.85%
+22.84%+30.56%
+21.42%+30.36%
+23.54%+33.83%
Max drawdown
HELX
GNOM
-6.59%-8.57%
-17.89%-18.16%
-29.16%-43.10%
-58.16%-71.04%
Max drawdown duration
HELX
GNOM
28d32d
206d145d
458d674d
1814d1818d
Trading data

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HELX
GNOM
Last sale
9/14/2026 at 1:30 PM
$41.56
$63.67
Previous close
09/11/2026
$40.99
$62.22
Consolidated volume
09/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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HELX
is actively managed and doesn’t replicate an index

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HELX
GNOM
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 9/14/2026 at 1:30 PM
Live
Closed
HELX
GNOM
Last price
$41.56
$63.67
1D performance
+1.40%
+2.33%
AuM$30.73 M$93.74 M
E/R0.5%0.5%
Characteristics
HELX
GNOM
Management strategyActivePassive
ProviderFranklin TempletonGlobal X
Benchmark-Solactive Genomics Index
N° of holdings66-
Asset class-Equities
Trailing 12m distribution yield
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Inception dateFebruary 25, 2020April 5, 2019
ESGNoNo
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Exposure

Countries

HELX
USA
86.99%
Other
13.01%
GNOM
Data will be available soon

Sectors

HELX
Healthcare
96.35%
Other
3.65%
GNOM
Data will be available soon
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Diversification

HELX

Total weight of top 15 holdings out of 15

60.19%
GNOM
Data will be available soon

Top 15 holdings

Data as of July 31, 2026
HELX
Guardant Health, Inc.
9.10%
Natera, Inc.
7.31%
Krystal Biotech, Inc.
6.17%
Ligand Pharmaceuticals, Inc.
4.48%
Adaptive Biotechnologies Corp.
4.33%
BridgeBio Pharma, Inc.
4.08%
United Therapeutics Corp.
3.52%
Eli Lilly & Co.
3.04%
Vertex Pharmaceuticals, Inc.
2.73%
SAMSUNG BIOLOGICS Co., Ltd.
2.72%
Travere Therapeutics, Inc.
2.67%
Corteva, Inc.
2.65%
AstraZeneca PLC
2.49%
Twist Bioscience Corp.
2.47%
Medpace Holdings, Inc.
2.44%
GNOM
Data will be available soon
Frequently asked questions about HELX and GNOM

How have the HELX and GNOM ETFs performed in 2026?

As of September 11, 2026, HELX is up 12.93% year-to-date (YTD), while GNOM has returned 36.95%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or GNOM?

Year-to-date, the HELX ETF saw +$6M in flows, compared to +$21M for GNOM.

Which ETF is more volatile: HELX or GNOM?

Over the past year, HELX had a volatility of 22.84%, while GNOM experienced 30.56%.

Which ETF is bigger: HELX or GNOM?

As of September 11, 2026, HELX holds $30.73 M in assets under management (AUM), while GNOM manages $93.74 M.

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