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HELXvsFMEDETF Comparison

ETF 1
HELX

Franklin Genomic Advancements ETF

This fund is part of
BioTech & Genomics
-0.67%
VS
ETF 2
FMED

Fidelity Disruptive Medicine ETF

This fund is part of
Multiple Trends
+1.93%

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. Fidelity Disruptive Medicine ETF (FMED) is part of the Multiple Trends segment. HELX's top 3 sector exposures are Health Care, Materials and Information Technology. In contrast, FMED's top sector exposures are Health Care,  Both HELX and FMED have the same Total Expense Ratio (TER) of 0.5%. HELX is down -7.69% year-to-date (YTD) with +$2M in YTD flows. FMED performs better with -7.18% YTD performance, and - in YTD flows. Run a side-by-side ETF comparison of HELX and FMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs FMED performance and flow charts

Performance

-20246810%Mar 24Mar 31Apr 8Apr 15Apr 22

Cumulative Flows

Mar 24Mar 31Apr 8Apr 15Apr 22

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 04/24/2026
1M3MYTD1Y3Y5Y
Perf.
HELX
FMED
+5.41%+4.85%
-10.90%-9.73%
-7.69%-7.18%
+23.56%+6.63%
+9.47%n/a
-30.03%n/a
Flows
HELX
FMED
--
--
+$2M-
+$8M+$5M
+$9M-
+$14M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
HELX
FMED
+24.83%+22.74%
+20.80%+18.01%
+20.28%n/a
+23.68%n/a
Max drawdown
HELX
FMED
-16.86%-15.41%
-17.89%-17.78%
-29.16%n/a
-58.50%n/a
Max drawdown duration
HELX
FMED
88d88d
145d145d
458dn/a
1690dn/a
Trading data

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HELX
FMED
Last sale
4/24/2026 at 7:59 PM
$33.52
$25.13
Previous close
04/24/2026
$33.42
$25.15
Consolidated volume
04/24/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
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Main metrics
Last update 4/24/2026 at 7:59 PM
Live
Closed
HELX
FMED
Last price
$33.52
$25.13
1D performance
+0.32%
-0.06%
AuM$21.77 M$58.44 M
E/R0.5%0.5%
Characteristics
HELX
FMED
Management strategyActiveActive
ProviderFranklin TempletonFidelity
Benchmark--
N° of holdings5150
Asset class--
Trailing 12m distribution yield
Join
Join
Inception dateFebruary 25, 2020June 12, 2023
ESGNoNo
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Exposure

Countries

HELX
USA
87.6%
Other
12.4%
FMED
USA
87.06%
Other
12.94%

Sectors

HELX
Health Care
89.74%
Other
10.26%
FMED
Health Care
81.28%
Other
18.72%
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Diversification

HELX

Total weight of top 15 holdings out of 15

60.42%
FMED

Total weight of top 15 holdings out of 15

47.75%

Top 15 holdings

Data as of March 31, 2026
HELX
NATERA
6.89%
GUARDANT HEALTH INC
6.82%
KRYSTAL BIOTECH INC
5.46%
UTD THERAPEUT
4.40%
BRIDGEBIO PHARMA
4.36%
INSMED
4.31%
LIGAND PHARMACEUTICALS
3.80%
SAMSUNG BIOLOGICS CO LTD
3.37%
ADAPTIVE BIOTECHNOLOGIES
3.32%
ASTRAZENECA
3.24%
VERTEX PHARMACEUTICALS
3.20%
MEDPACE HOLDINGS INC
3.05%
CORTEVA INC
2.81%
ALNYLAM PHARMACEUTICALS
2.71%
REGENERON PHARMACEUTICALS
2.67%
FMED
UCB
4.43%
DANAHER
4.10%
BOSTON SCIENTIFIC
4.08%
COGENT BIOSCIENCES
3.99%
US04016X1019
3.88%
ALNYLAM PHARMACEUTICALS
3.53%
INTUITIVE SURGICAL
3.33%
VEEVA SYSTEMS IN
3.18%
MODERNA INC
2.67%
LIFESTANCE HEALTH GROUP
2.65%
US9467841055
2.60%
EDWARDS LIFESCIENCES
2.54%
INSULET
2.44%
VAXCYTE
2.20%
INSMED
2.14%
Frequently asked questions about HELX and FMED

How have the HELX and FMED ETFs performed in 2026?

As of April 24, 2026, HELX is down -7.69% year-to-date (YTD), while FMED has lost -7.18%. That puts FMED better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or FMED?

Year-to-date, the HELX ETF saw +$2M in flows, compared to - for FMED.

Which ETF is more volatile: HELX or FMED?

Over the past year, HELX had a volatility of 20.8%, while FMED experienced 18.01%.

Which ETF is bigger: HELX or FMED?

As of April 24, 2026, HELX holds $21.77 M in assets under management (AUM), while FMED manages $58.44 M.

What sectors do the HELX and FMED ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, FMED focuses on Health Care.

What are the top holdings of the HELX ETF and FMED ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. FMED holds in its top three: UCB, DANAHER and BOSTON SCIENTIFIC.

Which ETF is more diversified: HELX or FMED?

HELX holds 60 securities with 60.42% of its assets in the top 15. FMED has 66 securities and a top 15 weight of 47.75%.

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