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HELXvsFMEDETF Comparison

ETF 1
HELX

Franklin Genomic Advancements ETF

This fund is part of
BioTech & Genomics
+3.8%
VS
ETF 2
FMED

Fidelity Disruptive Medicine ETF

This fund is part of
Multiple Trends
+5.9%

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. Fidelity Disruptive Medicine ETF (FMED) is part of the Multiple Trends segment. HELX's top 3 sector exposures are Healthcare, Non-Energy Materials and Technology. In contrast, FMED's top sector exposures are Healthcare,  Both HELX and FMED have the same Total Expense Ratio (TER) of 0.5%. HELX is up 9.3% year-to-date (YTD) with +$6M in YTD flows. FMED performs worse with 5.96% YTD performance, and -$17M in YTD flows. Run a side-by-side ETF comparison of HELX and FMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs FMED performance and flow charts

Performance

-4.0-2.00.02.04.06.0%Jun 30Jul 8Jul 15Jul 22Jul 29

Cumulative Flows

0500,0001,000,0001,500,0002,000,000Jun 30Jul 8Jul 15Jul 22Jul 29

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Historic performance and flows
Data as of 07/30/2026
1M3MYTD1Y3Y5Y
Perf.
HELX
FMED
-0.62%+0.45%
+18.71%+15.63%
+9.30%+5.96%
+41.04%+19.83%
+26.87%+13.57%
-25.32%n/a
Flows
HELX
FMED
+$2M-
+$4M-$17M
+$6M-$17M
+$10M-$14M
+$13M-$3M
+$18M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
HELX
FMED
+24.21%+21.64%
+21.83%+19.54%
+20.99%+18.58%
+23.58%n/a
Max drawdown
HELX
FMED
-6.59%-5.92%
-17.89%-17.78%
-29.16%-21.33%
-58.50%n/a
Max drawdown duration
HELX
FMED
21d21d
206d212d
458d210d
1787dn/a
Trading data

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HELX
FMED
Last sale
7/30/2026 at 1:30 PM
$39.75
Previous close
07/30/2026
$38.89
Consolidated volume
07/30/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
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Main metrics
Last update 7/30/2026 at 1:30 PM
Live
Closed
HELX
FMED
Last price
$39.75
1D performance
+2.20%
AuM$29.75 M$46.62 M
E/R0.5%0.5%
Characteristics
HELX
FMED
Management strategyActiveActive
ProviderFranklin TempletonFidelity
Benchmark--
N° of holdings6169
Asset class--
Trailing 12m distribution yield
Join
Join
Inception dateFebruary 25, 2020June 12, 2023
ESGNoNo
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Exposure

Countries

HELX
USA
87.84%
Other
12.16%
FMED
USA
83.89%
Other
16.11%

Sectors

HELX
Healthcare
96.75%
Other
3.25%
FMED
Healthcare
100%
Other
-0%
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Diversification

HELX

Total weight of top 15 holdings out of 15

59.93%
FMED

Total weight of top 15 holdings out of 15

41.87%

Top 15 holdings

Data as of June 30, 2026
HELX
Guardant Health, Inc.
9.30%
Natera, Inc.
7.40%
Krystal Biotech, Inc.
6.51%
Ligand Pharmaceuticals, Inc.
4.56%
Adaptive Biotechnologies Corp.
4.01%
United Therapeutics Corp.
3.61%
BridgeBio Pharma, Inc.
3.39%
Eli Lilly & Co.
3.05%
Twist Bioscience Corp.
2.84%
Vertex Pharmaceuticals, Inc.
2.79%
Travere Therapeutics, Inc.
2.76%
AstraZeneca PLC
2.76%
Insmed, Inc.
2.43%
Corteva, Inc.
2.26%
SAMSUNG BIOLOGICS Co., Ltd.
2.26%
FMED
Lifestance Health Group, Inc.
5.11%
10X Genomics, Inc.
3.56%
Danaher Corp.
3.29%
UCB SA
3.09%
Cogent Biosciences, Inc.
2.79%
Bio-Techne Corp.
2.76%
Moderna, Inc.
2.69%
Intuitive Surgical, Inc.
2.49%
argenx SE
2.43%
Alnylam Pharmaceuticals, Inc.
2.41%
Kymera Therapeutics, Inc.
2.36%
UnitedHealth Group, Inc.
2.27%
Thermo Fisher Scientific, Inc.
2.24%
Ascendis Pharma A/S
2.21%
Legend Biotech Corp.
2.17%
Frequently asked questions about HELX and FMED

How have the HELX and FMED ETFs performed in 2026?

As of July 30, 2026, HELX is up 9.3% year-to-date (YTD), while FMED has returned 5.96%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or FMED?

Year-to-date, the HELX ETF saw +$6M in flows, compared to -$17M for FMED.

Which ETF is more volatile: HELX or FMED?

Over the past year, HELX had a volatility of 21.83%, while FMED experienced 19.54%.

Which ETF is bigger: HELX or FMED?

As of July 30, 2026, HELX holds $29.75 M in assets under management (AUM), while FMED manages $46.62 M.

What sectors do the HELX and FMED ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, FMED focuses on Healthcare.

What are the top holdings of the HELX ETF and FMED ETF?

HELX top holdings include Guardant Health, Inc., Natera, Inc. and Krystal Biotech, Inc.. FMED holds in its top three: Lifestance Health Group, Inc., 10X Genomics, Inc. and Danaher Corp..

Which ETF is more diversified: HELX or FMED?

HELX holds 61 securities with 59.93% of its assets in the top 15. FMED has 69 securities and a top 15 weight of 41.87%.

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