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HELXvsFBTETF Comparison

ETF 1
HELX

Franklin Genomic Advancements ETF

This fund is part of
BioTech & Genomics
-0.67%
VS
ETF 2
FBT

First Trust NYSE Arca Biotechnology Index Fund ETF

This fund is part of
US Health Care
-1.08%

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. First Trust NYSE Arca Biotechnology Index Fund ETF (FBT) is part of the US Health Care segment. HELX's top 3 sector exposures are Health Care, Materials and Information Technology. In contrast, FBT's top sector exposures are Health Care,  HELX is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.54% for FBT. HELX is down -7.69% year-to-date (YTD) with +$2M in YTD flows. FBT performs better with -0.93% YTD performance, and +$1.07B in YTD flows. Run a side-by-side ETF comparison of HELX and FBT below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs FBT performance and flow charts

Performance

-20246810%Mar 23Mar 30Apr 7Apr 14Apr 21

Cumulative Flows

-20 M-15 M-10 M-5 M0 MMar 23Mar 30Apr 7Apr 14Apr 21

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 04/24/2026
1M3MYTD1Y3Y5Y
Perf.
HELX
FBT
+5.41%+6.35%
-10.90%-6.86%
-7.69%-0.93%
+23.56%+29.41%
+9.47%+31.14%
-30.03%+24.73%
Flows
HELX
FBT
--$20M
-+$101M
+$2M+$1.07B
+$8M+$1.08B
+$9M+$617M
+$14M+$289M
Volatility and drawdown
3M1Y3Y5Y
Volatility
HELX
FBT
+24.83%+23.37%
+20.80%+21.80%
+20.28%+20.22%
+23.68%+21.89%
Max drawdown
HELX
FBT
-16.86%-13.39%
-17.89%-14.27%
-29.16%-19.92%
-58.50%-29.98%
Max drawdown duration
HELX
FBT
88d87d
145d91d
458d237d
1690d1243d
Trading data

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HELX
FBT
Last sale
4/24/2026 at 7:59 PM
$33.52
$204.75
Previous close
04/24/2026
$33.42
$204.04
Consolidated volume
04/24/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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HELX
is actively managed and doesn’t replicate an index

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HELX
FBT
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/24/2026 at 7:59 PM
Live
Closed
HELX
FBT
Last price
$33.52
$204.75
1D performance
+0.32%
+0.35%
AuM$21.77 M$2.31 B
E/R0.5%0.54%
Characteristics
HELX
FBT
Management strategyActivePassive
ProviderFranklin TempletonFirst Trust
Benchmark-NYSE Arca Biotechnology Index
N° of holdings5128
Asset class-Equities
Trailing 12m distribution yield
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Inception dateFebruary 25, 2020June 19, 2006
ESGNoNo
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Exposure

Countries

HELX
USA
87.6%
Other
12.4%
FBT
USA
95.76%
Other
4.24%

Sectors

HELX
Health Care
89.74%
Other
10.26%
FBT
Health Care
90.59%
Other
9.41%

Diversification

HELX

Total weight of top 15 holdings out of 15

60.42%
FBT

Total weight of top 15 holdings out of 15

56.66%

Top 15 holdings

Data as of March 31, 2026
HELX
NATERA
6.89%
GUARDANT HEALTH INC
6.82%
KRYSTAL BIOTECH INC
5.46%
UTD THERAPEUT
4.40%
BRIDGEBIO PHARMA
4.36%
INSMED
4.31%
LIGAND PHARMACEUTICALS
3.80%
SAMSUNG BIOLOGICS CO LTD
3.37%
ADAPTIVE BIOTECHNOLOGIES
3.32%
ASTRAZENECA
3.24%
VERTEX PHARMACEUTICALS
3.20%
MEDPACE HOLDINGS INC
3.05%
CORTEVA INC
2.81%
ALNYLAM PHARMACEUTICALS
2.71%
REGENERON PHARMACEUTICALS
2.67%
FBT
MODERNA INC
5.14%
ALKERMES
4.16%
UTD THERAPEUT
4.15%
GILEAD SCIENCES
4.08%
CORCEPT THERAPEUTICS
3.94%
AXSOME THERA CMN STK
3.91%
AMGEN-T
3.81%
EXELIXIS
3.52%
KRYSTAL BIOTECH INC
3.49%
BIOGEN INC
3.45%
REGENERON PHARMACEUTICALS
3.44%
NEUROCRINE BIOSCIENCES
3.44%
BIOMARIN PHARMACEUTICAL
3.42%
VERTEX PHARMACEUTICALS
3.39%
US04016X1019
3.32%
Frequently asked questions about HELX and FBT

How have the HELX and FBT ETFs performed in 2026?

As of April 24, 2026, HELX is down -7.69% year-to-date (YTD), while FBT has lost -0.93%. That puts FBT better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or FBT?

Year-to-date, the HELX ETF saw +$2M in flows, compared to +$1.07B for FBT.

Which ETF is more volatile: HELX or FBT?

Over the past year, HELX had a volatility of 20.8%, while FBT experienced 21.8%.

Which ETF is bigger: HELX or FBT?

As of April 24, 2026, HELX holds $21.77 M in assets under management (AUM), while FBT manages $2.31 B.

What sectors do the HELX and FBT ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, FBT focuses on Health Care.

What are the top holdings of the HELX ETF and FBT ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. FBT holds in its top three: MODERNA INC, ALKERMES and UTD THERAPEUT.

Which ETF is more diversified: HELX or FBT?

HELX holds 60 securities with 60.42% of its assets in the top 15. FBT has 30 securities and a top 15 weight of 56.66%.

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