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HELXvsEKGETF Comparison

ETF 1
HELX

Franklin Genomic Advancements ETF

This fund is part of
BioTech & Genomics
-0.67%
VS
ETF 2
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
-0.51%

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) is part of the Healthcare Technology segment. HELX's top 3 sector exposures are Health Care, Materials and Information Technology. In contrast, EKG's top sector exposures are Health Care, Financials  HELX is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.65% for EKG. HELX is down -7.69% year-to-date (YTD) with +$2M in YTD flows. EKG performs worse with -11.32% YTD performance, and - in YTD flows. Run a side-by-side ETF comparison of HELX and EKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs EKG performance and flow charts

Performance

-50510%Mar 24Mar 31Apr 8Apr 15Apr 22

Cumulative Flows

Mar 24Mar 31Apr 8Apr 15Apr 22

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Historic performance and flows
Data as of 04/24/2026
1M3MYTD1Y3Y5Y
Perf.
HELX
EKG
+5.41%+1.63%
-10.90%-14.29%
-7.69%-11.32%
+23.56%+6.73%
+9.47%-6.06%
-30.03%n/a
Flows
HELX
EKG
--
--
+$2M-
+$8M-$25K
+$9M+$1M
+$14M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
HELX
EKG
+24.83%+25.81%
+20.80%+21.14%
+20.28%+22.97%
+23.68%n/a
Max drawdown
HELX
EKG
-16.86%-19.93%
-17.89%-21.99%
-29.16%-34.97%
-58.50%n/a
Max drawdown duration
HELX
EKG
88d88d
145d107d
458d563d
1690dn/a
Trading data

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HELX
EKG
Last sale
4/24/2026 at 7:59 PM
$33.52
$16.81
Previous close
04/24/2026
$33.42
$16.64
Consolidated volume
04/24/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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HELX
is actively managed and doesn’t replicate an index

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HELX
EKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/24/2026 at 7:59 PM
Live
Closed
HELX
EKG
Last price
$33.52
$16.81
1D performance
+0.32%
+1.03%
AuM$21.77 M$2.53 M
E/R0.5%0.65%
Characteristics
HELX
EKG
Management strategyActivePassive
ProviderFranklin TempletonFirst Trust
Benchmark-Nasdaq Lux Health Tech Index
N° of holdings5133
Asset class-Equities
Trailing 12m distribution yield
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Inception dateFebruary 25, 2020March 22, 2022
ESGNoNo
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Exposure

Countries

HELX
USA
87.6%
Other
12.4%
EKG
USA
94.35%
Other
5.65%

Sectors

HELX
Health Care
89.74%
Other
10.26%
EKG
Health Care
86.01%
Other
13.99%
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Diversification

HELX

Total weight of top 15 holdings out of 15

60.42%
EKG

Total weight of top 15 holdings out of 15

74.16%

Top 15 holdings

Data as of March 31, 2026
HELX
NATERA
6.89%
GUARDANT HEALTH INC
6.82%
KRYSTAL BIOTECH INC
5.46%
UTD THERAPEUT
4.40%
BRIDGEBIO PHARMA
4.36%
INSMED
4.31%
LIGAND PHARMACEUTICALS
3.80%
SAMSUNG BIOLOGICS CO LTD
3.37%
ADAPTIVE BIOTECHNOLOGIES
3.32%
ASTRAZENECA
3.24%
VERTEX PHARMACEUTICALS
3.20%
MEDPACE HOLDINGS INC
3.05%
CORTEVA INC
2.81%
ALNYLAM PHARMACEUTICALS
2.71%
REGENERON PHARMACEUTICALS
2.67%
EKG
IQVIA HOLDINGS INC
8.48%
VEEVA SYSTEMS IN
8.34%
INTUITIVE SURGICAL
8.11%
RESMED
7.65%
DEXCOM
7.47%
NATERA
4.30%
GUARDANT HEALTH INC
4.27%
ILLUMINA
4.14%
GLOBUS MEDICAL
4.04%
ALIGN TECHNOLOGY
4.00%
INSULET
3.69%
US88023B1035
3.45%
IRHYTHM TECHNOLOGIES
2.14%
HIMS & HERS HEALTH INC
2.13%
OSCAR HEALTH
1.95%
Frequently asked questions about HELX and EKG

How have the HELX and EKG ETFs performed in 2026?

As of April 24, 2026, HELX is down -7.69% year-to-date (YTD), while EKG has lost -11.32%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or EKG?

Year-to-date, the HELX ETF saw +$2M in flows, compared to - for EKG.

Which ETF is more volatile: HELX or EKG?

Over the past year, HELX had a volatility of 20.8%, while EKG experienced 21.14%.

Which ETF is bigger: HELX or EKG?

As of April 24, 2026, HELX holds $21.77 M in assets under management (AUM), while EKG manages $2.53 M.

What sectors do the HELX and EKG ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, EKG focuses on Health Care.

What are the top holdings of the HELX ETF and EKG ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. EKG holds in its top three: IQVIA HOLDINGS INC, VEEVA SYSTEMS IN and INTUITIVE SURGICAL.

Which ETF is more diversified: HELX or EKG?

HELX holds 60 securities with 60.42% of its assets in the top 15. EKG has 36 securities and a top 15 weight of 74.16%.

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