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HELXvsEKGETF Comparison

ETF 1

HELX

Franklin Genomic Advancements ETF

This fund is part of

BioTech & Genomics

+0.29%

Full HELX fund page

VS

ETF 2

EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of

Healthcare Technology

+0.38%

Full EKG fund page

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) is part of the Healthcare Technology segment. HELX's top 3 sector exposures are Healthcare, Non-Energy Materials and Technology. In contrast, EKG's top sector exposures are Healthcare. HELX is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.65% for EKG. HELX is up 12.93% year-to-date (YTD) with +$6M in YTD flows. EKG performs worse with 11.43% YTD performance, and +$963K in YTD flows. Run a side-by-side ETF comparison of HELX and EKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs EKG performance and flow charts

Performance

Cumulative Flows

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Data Services

Historic performance and flows

Data as of 09/11/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HELX EKG	-1.05%+0.39%	+15.09%+21.17%	+12.93%+11.43%	+33.15%+22.85%	+37.37%+36.04%	-26.59%n/a
Flows	HELX EKG	--	+$4M+$963K	+$6M+$963K	+$8M+$963K	+$15M+$2M	+$4M-

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HELX EKG	+24.44%+26.19%	+22.84%+23.51%	+21.42%+23.84%	+23.54%n/a
Max drawdown	HELX EKG	-6.59%-7.45%	-17.89%-22.11%	-29.16%-24.32%	-58.16%n/a
Max drawdown duration	HELX EKG	28d28d	206d208d	458d264d	1814dn/a

Trading data

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	HELX	EKG
Last sale 9/14/2026 at 1:30 PM	$41.56	$21.35
Previous close 09/11/2026	$40.99	$21.17
Consolidated volume 09/11/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of August 31, 2026

1-year trailing difference

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HELX

is actively managed and doesn’t replicate an index

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	HELX	EKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 9/14/2026 at 1:30 PM

Live

Closed

	HELX	EKG
Last price	$41.56	$21.35
1D performance	+1.40%	+0.83%
AuM	$30.73 M	$4.23 M
E/R	0.5%	0.65%

Characteristics

	HELX	EKG
Management strategy	Active	Passive
Provider	Franklin Templeton	First Trust
Benchmark	-	Nasdaq Lux Health Tech Index
N° of holdings	66	37
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	February 25, 2020	March 22, 2022
ESG	No	No

More HELX data on Trackinsight

More EKG data on Trackinsight

Exposure

Countries

HELX

USA

86.99%

Other

13.01%

EKG

USA

95.72%

Other

4.28%

Sectors

HELX

Healthcare

96.35%

Other

3.65%

EKG

Healthcare

98.67%

Other

1.33%

Diversification

HELX

Total weight of top 15 holdings out of 15

60.19%

EKG

Total weight of top 15 holdings out of 15

74.55%

Top 15 holdings

Data as of July 31, 2026

HELX

Guardant Health, Inc.

9.10%

Natera, Inc.

7.31%

Krystal Biotech, Inc.

6.17%

Ligand Pharmaceuticals, Inc.

4.48%

Adaptive Biotechnologies Corp.

4.33%

BridgeBio Pharma, Inc.

4.08%

United Therapeutics Corp.

3.52%

Eli Lilly & Co.

3.04%

Vertex Pharmaceuticals, Inc.

2.73%

SAMSUNG BIOLOGICS Co., Ltd.

2.72%

Travere Therapeutics, Inc.

2.67%

Corteva, Inc.

2.65%

AstraZeneca PLC

2.49%

Twist Bioscience Corp.

2.47%

Medpace Holdings, Inc.

2.44%

EKG

IQVIA Holdings, Inc.

9.37%

Veeva Systems, Inc.

9.01%

DexCom, Inc.

8.04%

Guardant Health, Inc.

5.85%

ResMed, Inc.

5.83%

Illumina, Inc.

5.19%

Natera, Inc.

5.11%

Intuitive Surgical, Inc.

4.87%

Oscar Health, Inc.

3.90%

Tempus AI, Inc.

3.64%

QIAGEN NV

2.95%

Globus Medical, Inc.

2.94%

Align Technology, Inc.

2.74%

10X Genomics, Inc.

2.57%

Hims & Hers Health, Inc.

2.54%

Frequently asked questions about HELX and EKG

How have the HELX and EKG ETFs performed in 2026?

As of September 11, 2026, HELX is up 12.93% year-to-date (YTD), while EKG has returned 11.43%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or EKG?

Year-to-date, the HELX ETF saw +$6M in flows, compared to +$963K for EKG.

Which ETF is more volatile: HELX or EKG?

Over the past year, HELX had a volatility of 22.84%, while EKG experienced 23.51%.

Which ETF is bigger: HELX or EKG?

As of September 11, 2026, HELX holds $30.73 M in assets under management (AUM), while EKG manages $4.23 M.

What sectors do the HELX and EKG ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, EKG focuses on Healthcare.

What are the top holdings of the HELX ETF and EKG ETF?

HELX top holdings include Guardant Health, Inc., Natera, Inc. and Krystal Biotech, Inc.. EKG holds in its top three: IQVIA Holdings, Inc., Veeva Systems, Inc. and DexCom, Inc..

HELXvsEKGETF Comparison

Franklin Genomic Advancements ETF

First Trust Nasdaq Lux Digital Health Solutions ETF

HELX vs EKG performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HELX and EKG ETFs performed in 2026?

As of September 11, 2026, HELX is up 12.93% year-to-date (YTD), while EKG has returned 11.43%. That puts HELX better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or EKG?

Year-to-date, the HELX ETF saw +$6M in flows, compared to +$963K for EKG.

Which ETF is more volatile: HELX or EKG?

Over the past year, HELX had a volatility of 22.84%, while EKG experienced 23.51%.

Which ETF is bigger: HELX or EKG?

As of September 11, 2026, HELX holds $30.73 M in assets under management (AUM), while EKG manages $4.23 M.

What sectors do the HELX and EKG ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, EKG focuses on Healthcare.

What are the top holdings of the HELX ETF and EKG ETF?

HELX top holdings include Guardant Health, Inc., Natera, Inc. and Krystal Biotech, Inc.. EKG holds in its top three: IQVIA Holdings, Inc., Veeva Systems, Inc. and DexCom, Inc..

Which ETF is more diversified: HELX or EKG?

HELX holds 66 securities with 60.19% of its assets in the top 15. EKG has 37 securities and a top 15 weight of 74.55%.

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