BROUGHT TO YOU BY:

ETF Portfolio Builder

New

ETF Portfolio Builder

New

HELXvsEKGETF Comparison

ETF 1

HELX

Franklin Genomic Advancements ETF

This fund is part of

BioTech & Genomics

-5.05%

Full HELX fund page

VS

ETF 2

EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of

Healthcare Technology

-0.67%

Full EKG fund page

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) is part of the Healthcare Technology segment. HELX's top 3 sector exposures are Healthcare, Non-Energy Materials and Technology. In contrast, EKG's top sector exposures are Healthcare. HELX is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.65% for EKG. HELX is up 24.75% year-to-date (YTD) with +$8M in YTD flows. EKG performs better with 31.66% YTD performance, and +$6M in YTD flows. Run a side-by-side ETF comparison of HELX and EKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

Find out how industry players manage ETF portfolios. Discover our library of Model portfolios

HELX vs EKG performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 10/30/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HELX EKG	+1.74%+5.76%	+14.13%+28.41%	+24.75%+31.66%	+30.17%+37.20%	+78.56%+107.33%	-15.82%n/a
Flows	HELX EKG	+$2M+$5M	+$2M+$5M	+$8M+$6M	+$8M+$6M	+$17M+$7M	+$8M-

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HELX EKG	+27.48%+25.55%	+24.12%+24.43%	+21.94%+23.86%	+23.68%n/a
Max drawdown	HELX EKG	-8.93%-5.73%	-17.89%-22.11%	-29.16%-24.32%	-55.27%n/a
Max drawdown duration	HELX EKG	22d21d	206d208d	458d264d	1823dn/a

Trading data

Create an account to view trading data

Join for free

	HELX	EKG
Last sale 10/30/2026 at 1:30 PM	$45.25	$23.93
Previous close 10/29/2026	$46.01	$25.00
Consolidated volume 10/29/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of September 30, 2026

1-year trailing difference

Create an account to view replication metrics

Join for free

HELX

is actively managed and doesn’t replicate an index

Create an account to view replication quality

Join for free

	HELX	EKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 10/30/2026 at 1:30 PM

Live

Closed

	HELX	EKG
Last price	$45.25	$23.93
1D performance	-1.65%	-4.30%
AuM	$36.21 M	$10.01 M
E/R	0.5%	0.65%

Characteristics

	HELX	EKG
Management strategy	Active	Passive
Provider	Franklin Templeton	First Trust
Benchmark	-	Nasdaq Lux Health Tech Index
N° of holdings	66	51
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	February 25, 2020	March 22, 2022
ESG	No	No

More HELX data on Trackinsight

More EKG data on Trackinsight

Exposure

Countries

HELX

USA

90.13%

Other

9.87%

EKG

USA

96.91%

Other

3.09%

Sectors

HELX

Healthcare

97.01%

Other

2.99%

EKG

Healthcare

99.9%

Other

0.1%

Diversification

HELX

Total weight of top 15 holdings out of 15

61.42%

EKG

Total weight of top 15 holdings out of 15

72.5%

Top 15 holdings

Data as of September 30, 2026

HELX

Natera, Inc.

10.25%

Guardant Health, Inc.

9.72%

Krystal Biotech, Inc.

5.32%

Twist Bioscience Corp.

5.01%

Adaptive Biotechnologies Corp.

4.95%

Ligand Pharmaceuticals, Inc.

4.33%

BridgeBio Pharma, Inc.

2.79%

Travere Therapeutics, Inc.

2.72%

Medpace Holdings, Inc.

2.64%

Vertex Pharmaceuticals, Inc.

2.62%

Corteva, Inc.

2.33%

Eli Lilly & Co.

2.25%

Tempus AI, Inc.

2.25%

United Therapeutics Corp.

2.20%

Repligen Corp.

2.04%

EKG

Natera, Inc.

9.62%

Intuitive Surgical, Inc.

8.07%

IQVIA Holdings, Inc.

7.56%

Veeva Systems, Inc.

7.47%

DexCom, Inc.

7.18%

Illumina, Inc.

4.71%

Guardant Health, Inc.

4.16%

ResMed, Inc.

3.48%

Globus Medical, Inc.

3.21%

Tempus AI, Inc.

3.06%

QIAGEN NV

2.99%

Twist Bioscience Corp.

2.85%

Align Technology, Inc.

2.75%

Insulet Corp.

2.73%

Oscar Health, Inc.

2.66%

Frequently asked questions about HELX and EKG

How have the HELX and EKG ETFs performed in 2026?

As of October 30, 2026, HELX is up 24.75% year-to-date (YTD), while EKG has returned 31.66%. That puts EKG better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or EKG?

Year-to-date, the HELX ETF saw +$8M in flows, compared to +$6M for EKG.

Which ETF is more volatile: HELX or EKG?

Over the past year, HELX had a volatility of 24.12%, while EKG experienced 24.43%.

Which ETF is bigger: HELX or EKG?

As of October 30, 2026, HELX holds $36.21 M in assets under management (AUM), while EKG manages $10.01 M.

What sectors do the HELX and EKG ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, EKG focuses on Healthcare.

What are the top holdings of the HELX ETF and EKG ETF?

HELX top holdings include Natera, Inc., Guardant Health, Inc. and Krystal Biotech, Inc.. EKG holds in its top three: Natera, Inc., Intuitive Surgical, Inc. and IQVIA Holdings, Inc..

HELXvsEKGETF Comparison

Franklin Genomic Advancements ETF

First Trust Nasdaq Lux Digital Health Solutions ETF

HELX vs EKG performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HELX and EKG ETFs performed in 2026?

As of October 30, 2026, HELX is up 24.75% year-to-date (YTD), while EKG has returned 31.66%. That puts EKG better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or EKG?

Year-to-date, the HELX ETF saw +$8M in flows, compared to +$6M for EKG.

Which ETF is more volatile: HELX or EKG?

Over the past year, HELX had a volatility of 24.12%, while EKG experienced 24.43%.

Which ETF is bigger: HELX or EKG?

As of October 30, 2026, HELX holds $36.21 M in assets under management (AUM), while EKG manages $10.01 M.

What sectors do the HELX and EKG ETFs invest in?

HELX leans toward sectors like Healthcare. Meanwhile, EKG focuses on Healthcare.

What are the top holdings of the HELX ETF and EKG ETF?

HELX top holdings include Natera, Inc., Guardant Health, Inc. and Krystal Biotech, Inc.. EKG holds in its top three: Natera, Inc., Intuitive Surgical, Inc. and IQVIA Holdings, Inc..

Which ETF is more diversified: HELX or EKG?

HELX holds 66 securities with 61.42% of its assets in the top 15. EKG has 51 securities and a top 15 weight of 72.5%.

ETFs’ Next Act: From Access to Selection