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HELXvsBBPETF Comparison

ETF 1
HELX

Franklin Genomic Advancements ETF

This fund is part of
BioTech & Genomics
-0.46%
VS
ETF 2
BBP

Virtus LifeSci Biotech Products ETF

This fund is part of
Tomorrow's Treatments
-1.28%

Franklin Genomic Advancements ETF (HELX) belongs to the BioTech & Genomics segment. Virtus LifeSci Biotech Products ETF (BBP) is part of the Tomorrow's Treatments segment. HELX's top 3 sector exposures are Health Care, Materials and Information Technology. In contrast, BBP's top sector exposures are Health Care,  HELX is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.79% for BBP. HELX is down -10.21% year-to-date (YTD) with +$2M in YTD flows. BBP performs better with 4.69% YTD performance, and +$12M in YTD flows. Run a side-by-side ETF comparison of HELX and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HELX vs BBP performance and flow charts

Performance

024681012%Mar 30Apr 7Apr 14Apr 21Apr 28

Cumulative Flows

0 M1 M2 M3 M4 MMar 30Apr 7Apr 14Apr 21Apr 28

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Historic performance and flows
Data as of 04/29/2026
1M3MYTD1Y3Y5Y
Perf.
HELX
BBP
+3.08%+6.54%
-11.68%+1.36%
-10.21%+4.69%
+19.60%+44.89%
+8.42%+62.35%
-29.88%+53.80%
Flows
HELX
BBP
-+$4M
-+$12M
+$2M+$12M
+$8M+$24M
+$9M+$27M
+$14M+$17M
Volatility and drawdown
3M1Y3Y5Y
Volatility
HELX
BBP
+24.97%+28.31%
+20.93%+24.02%
+20.24%+23.75%
+23.69%+26.18%
Max drawdown
HELX
BBP
-15.26%-9.59%
-17.89%-9.81%
-29.16%-25.54%
-58.50%-38.24%
Max drawdown duration
HELX
BBP
90d48d
150d36d
458d292d
1695d915d
Trading data

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HELX
BBP
Last sale
4/30/2026 at 1:30 PM
$33.40
$84.78
Previous close
04/29/2026
$32.57
$83.35
Consolidated volume
04/29/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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HELX
is actively managed and doesn’t replicate an index

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HELX
BBP
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/30/2026 at 1:30 PM
Live
Closed
HELX
BBP
Last price
$33.40
$84.78
1D performance
+2.55%
+1.72%
AuM$21.18 M$58.45 M
E/R0.5%0.79%
Characteristics
HELX
BBP
Management strategyActivePassive
ProviderFranklin TempletonVIRTUS Investment Partners
Benchmark-LifeSci Biotechnology Products Index
N° of holdings5156
Asset class-Equities
Trailing 12m distribution yield
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Inception dateFebruary 25, 2020December 16, 2014
ESGNoNo
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Exposure

Countries

HELX
USA
87.6%
Other
12.4%
BBP
USA
89.45%
Other
10.55%

Sectors

HELX
Health Care
89.74%
Other
10.26%
BBP
Health Care
88.78%
Other
11.22%
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Diversification

HELX

Total weight of top 15 holdings out of 15

60.42%
BBP

Total weight of top 15 holdings out of 15

33.42%

Top 15 holdings

Data as of March 31, 2026
HELX
NATERA
6.89%
GUARDANT HEALTH INC
6.82%
KRYSTAL BIOTECH INC
5.46%
UTD THERAPEUT
4.40%
BRIDGEBIO PHARMA
4.36%
INSMED
4.31%
LIGAND PHARMACEUTICALS
3.80%
SAMSUNG BIOLOGICS CO LTD
3.37%
ADAPTIVE BIOTECHNOLOGIES
3.32%
ASTRAZENECA
3.24%
VERTEX PHARMACEUTICALS
3.20%
MEDPACE HOLDINGS INC
3.05%
CORTEVA INC
2.81%
ALNYLAM PHARMACEUTICALS
2.71%
REGENERON PHARMACEUTICALS
2.67%
BBP
BIOCRYST PHARMACEUTICALS
2.50%
ROIVANT SCIENCES LTD
2.45%
SYNDAX PHARMACEUTICALS INC
2.40%
GILEAD SCIENCES
2.25%
GERON
2.24%
GB00BRXB0C07
2.23%
KALVISTA PHARMACEUTICALS INC
2.22%
AMGEN-T
2.20%
AXSOME THERA CMN STK
2.20%
AGIOS PHARMA/D
2.18%
BIOGEN INC
2.17%
UTD THERAPEUT
2.13%
LIGAND PHARMACEUTICALS
2.13%
BIOMARIN PHARMACEUTICAL
2.06%
EXELIXIS
2.05%
Frequently asked questions about HELX and BBP

How have the HELX and BBP ETFs performed in 2026?

As of April 29, 2026, HELX is down -10.21% year-to-date (YTD), while BBP has returned 4.69%. That puts BBP better performer ahead so far this year.

Which ETF is attracting more investor money: HELX or BBP?

Year-to-date, the HELX ETF saw +$2M in flows, compared to +$12M for BBP.

Which ETF is more volatile: HELX or BBP?

Over the past year, HELX had a volatility of 20.93%, while BBP experienced 24.02%.

Which ETF is bigger: HELX or BBP?

As of April 29, 2026, HELX holds $21.18 M in assets under management (AUM), while BBP manages $58.45 M.

What sectors do the HELX and BBP ETFs invest in?

HELX leans toward sectors like Health Care. Meanwhile, BBP focuses on Health Care.

What are the top holdings of the HELX ETF and BBP ETF?

HELX top holdings include NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC. BBP holds in its top three: BIOCRYST PHARMACEUTICALS, ROIVANT SCIENCES LTD and SYNDAX PHARMACEUTICALS INC.

Which ETF is more diversified: HELX or BBP?

HELX holds 60 securities with 60.42% of its assets in the top 15. BBP has 61 securities and a top 15 weight of 33.42%.

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