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GNOMvsXHEETF Comparison

ETF 1
GNOM

Global X Genomics & Biotechnology ETF

This fund is part of
BioTech & Genomics
+0.29%
VS
ETF 2
XHE

State Street SPDR S&P Health Care Equipment ETF

This fund is part of
US Health Care
-0.12%

Global X Genomics & Biotechnology ETF (GNOM) belongs to the BioTech & Genomics segment. State Street SPDR S&P Health Care Equipment ETF (XHE) is part of the US Health Care segment. In contrast, XHE's top sector exposures are Healthcare and Finance. GNOM is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.35% for XHE. GNOM is up 36.95% year-to-date (YTD) with +$21M in YTD flows. XHE performs worse with 2.14% YTD performance, and +$11M in YTD flows. Run a side-by-side ETF comparison of GNOM and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs XHE performance and flow charts

Performance

-50510%Aug 11Aug 18Aug 25Sep 1Sep 9

Cumulative Flows

-2 M0 M2 M4 MAug 11Aug 18Aug 25Sep 1Sep 9

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Historic performance and flows
Data as of 09/11/2026
1M3MYTD1Y3Y5Y
Perf.
GNOM
XHE
+4.57%-5.10%
+27.28%+9.79%
+36.95%+2.14%
+69.95%+9.32%
+43.87%+7.53%
-32.85%-30.21%
Flows
GNOM
XHE
+$2M+$3M
+$18M+$12M
+$21M+$11M
+$15M-$245K
-$54M-$266M
-$42M-$382M
Volatility and drawdown
3M1Y3Y5Y
Volatility
GNOM
XHE
+37.85%+24.14%
+30.56%+22.69%
+30.36%+22.22%
+33.83%+24.84%
Max drawdown
GNOM
XHE
-8.57%-7.53%
-18.16%-18.20%
-43.10%-24.35%
-71.04%-49.37%
Max drawdown duration
GNOM
XHE
32d23d
145d207d
674d565d
1818d1773d
Trading data

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GNOM
XHE
Last sale
9/14/2026 at 1:30 PM
$63.57
$91.43
Previous close
09/11/2026
$62.22
$90.01
Consolidated volume
09/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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GNOM
XHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 9/14/2026 at 1:30 PM
Live
Closed
GNOM
XHE
Last price
$63.57
$91.43
1D performance
+2.17%
+1.58%
AuM$93.74 M$168.78 M
E/R0.5%0.35%
Characteristics
GNOM
XHE
Management strategyPassivePassive
ProviderGlobal XState Street Investment Management
BenchmarkSolactive Genomics IndexS&P Health Care Equipment Select Industry Index
N° of holdings-66
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateApril 5, 2019January 26, 2011
ESGNoNo
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Exposure

Countries

GNOM
Data will be available soon
XHE
USA
93.56%
Other
6.44%

Sectors

GNOM
Data will be available soon
XHE
Healthcare
98.72%
Other
1.28%

Diversification

GNOM
Data will be available soon
XHE

Total weight of top 15 holdings out of 15

30.19%

Top 15 holdings

Data as of January 1, 1970
GNOM
Data will be available soon
XHE
AtriCure, Inc.
2.14%
Glaukos Corp.
2.13%
Dentsply Sirona, Inc.
2.08%
Enovis Corp.
2.07%
Integer Holdings Corp.
2.07%
Butterfly Network, Inc.
2.06%
Neogen Corp.
2.05%
Artivion, Inc.
2.05%
Baxter International, Inc.
2.01%
CONMED Corp.
1.99%
Merit Medical Systems, Inc.
1.98%
QuidelOrtho Corp.
1.94%
ICU Medical, Inc.
1.88%
Tandem Diabetes Care, Inc.
1.88%
Inspire Medical Systems, Inc.
1.85%
Frequently asked questions about GNOM and XHE

How have the GNOM and XHE ETFs performed in 2026?

As of September 11, 2026, GNOM is up 36.95% year-to-date (YTD), while XHE has returned 2.14%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or XHE?

Year-to-date, the GNOM ETF saw +$21M in flows, compared to +$11M for XHE.

Which ETF is more volatile: GNOM or XHE?

Over the past year, GNOM had a volatility of 30.56%, while XHE experienced 22.69%.

Which ETF is bigger: GNOM or XHE?

As of September 11, 2026, GNOM holds $93.74 M in assets under management (AUM), while XHE manages $168.78 M.

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