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GNOMvsPTHETF Comparison

ETF 1

GNOM

Global X Genomics & Biotechnology ETF

This fund is part of

BioTech & Genomics

+3.8%

Full GNOM fund page

VS

ETF 2

PTH

Invesco DWA Healthcare Momentum ETF

This fund is part of

US Health Care

-0.7%

Full PTH fund page

Global X Genomics & Biotechnology ETF (GNOM) belongs to the BioTech & Genomics segment. Invesco DWA Healthcare Momentum ETF (PTH) is part of the US Health Care segment. GNOM's top 3 sector exposures are Healthcare and Industrials. In contrast, PTH's top sector exposures are Healthcare GNOM is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.72% for PTH. GNOM is up 21.83% year-to-date (YTD) with +$18M in YTD flows. PTH performs worse with 19.17% YTD performance, and +$93M in YTD flows. Run a side-by-side ETF comparison of GNOM and PTH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs PTH performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 07/30/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	GNOM PTH	-2.19%-0.69%	+22.58%+17.11%	+21.83%+19.17%	+58.30%+60.51%	+14.80%+57.34%	-38.54%+10.70%
Flows	GNOM PTH	+$7M+$106M	+$19M+$99M	+$18M+$93M	+$13M+$99M	-$95M+$30M	-$862K-$185M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	GNOM PTH	+28.16%+29.64%	+26.78%+24.90%	+29.11%+25.71%	+33.32%+25.60%
Max drawdown	GNOM PTH	-8.57%-8.31%	-18.16%-11.91%	-43.10%-27.71%	-72.01%-50.10%
Max drawdown duration	GNOM PTH	24d41d	145d140d	674d353d	1792d1756d

Trading data

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	GNOM	PTH
Last sale 7/31/2026 at 1:30 PM	$54.17	$58.10
Previous close 07/30/2026	$55.39	$59.27
Consolidated volume 07/30/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of June 30, 2026

1-year trailing difference

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	GNOM	PTH
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 7/31/2026 at 1:30 PM

Live

Closed

	GNOM	PTH
Last price	$54.17	$58.10
1D performance	-2.21%	-1.97%
AuM	$81.18 M	$239.95 M
E/R	0.5%	0.72%

Characteristics

	GNOM	PTH
Management strategy	Passive	Passive
Provider	Global X	Invesco
Benchmark	Solactive Genomics Index	Dorsey Wright Healthcare Technical Leaders Index
N° of holdings	50	57
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	April 5, 2019	October 12, 2006
ESG	No	No

More GNOM data on Trackinsight

More PTH data on Trackinsight

Exposure

Countries

GNOM

USA

84.1%

Other

15.9%

PTH

USA

92.25%

Other

7.75%

Sectors

GNOM

Healthcare

99.75%

Other

0.25%

PTH

Healthcare

100%

Other

0%

Diversification

GNOM

Total weight of top 15 holdings out of 15

61.22%

PTH

Total weight of top 15 holdings out of 15

43.88%

Top 15 holdings

Data as of June 30, 2026

GNOM

Guardant Health, Inc.

5.78%

Twist Bioscience Corp.

5.09%

Illumina, Inc.

4.67%

Natera, Inc.

4.41%

Moderna, Inc.

4.22%

Veracyte, Inc.

4.12%

Bio-Techne Corp.

4.08%

Vertex Pharmaceuticals, Inc.

3.85%

Legend Biotech Corp.

3.82%

10X Genomics, Inc.

3.70%

Arrowhead Pharmaceuticals, Inc.

3.67%

BioMarin Pharmaceutical, Inc.

3.59%

Praxis Precision Medicines, Inc.

3.50%

CRISPR Therapeutics AG

3.36%

QIAGEN NV

3.35%

PTH

Roivant Sciences Ltd.

4.95%

Praxis Precision Medicines, Inc.

4.66%

Tango Therapeutics, Inc.

3.70%

SELLAS Life Sciences Group, Inc.

3.36%

United Therapeutics Corp.

2.91%

Tenet Healthcare Corp.

2.89%

Axsome Therapeutics, Inc.

2.74%

BrightSpring Health Services, Inc.

2.54%

Liquidia Corp.

2.52%

Moderna, Inc.

2.49%

Ionis Pharmaceuticals, Inc.

2.30%

Erasca, Inc.

2.29%

HCA Healthcare, Inc.

2.23%

Twist Bioscience Corp.

2.21%

Protagonist Therapeutics, Inc.

2.08%

Frequently asked questions about GNOM and PTH

How have the GNOM and PTH ETFs performed in 2026?

As of July 30, 2026, GNOM is up 21.83% year-to-date (YTD), while PTH has returned 19.17%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or PTH?

Year-to-date, the GNOM ETF saw +$18M in flows, compared to +$93M for PTH.

Which ETF is more volatile: GNOM or PTH?

Over the past year, GNOM had a volatility of 26.78%, while PTH experienced 24.9%.

Which ETF is bigger: GNOM or PTH?

As of July 30, 2026, GNOM holds $81.18 M in assets under management (AUM), while PTH manages $239.95 M.

What sectors do the GNOM and PTH ETFs invest in?

GNOM leans toward sectors like Healthcare. Meanwhile, PTH focuses on Healthcare.

What are the top holdings of the GNOM ETF and PTH ETF?

GNOM top holdings include Guardant Health, Inc., Twist Bioscience Corp. and Illumina, Inc.. PTH holds in its top three: Roivant Sciences Ltd., Praxis Precision Medicines, Inc. and Tango Therapeutics, Inc..

Which ETF is more diversified: GNOM or PTH?

GNOM holds 50 securities with 61.22% of its assets in the top 15. PTH has 57 securities and a top 15 weight of 43.88%.

Continued tightening of the U.S. labor market

September 23, 2022

PTH

GNOMvsPTHETF Comparison

Global X Genomics & Biotechnology ETF

Invesco DWA Healthcare Momentum ETF

GNOM vs PTH performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the GNOM and PTH ETFs performed in 2026?

As of July 30, 2026, GNOM is up 21.83% year-to-date (YTD), while PTH has returned 19.17%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or PTH?

Year-to-date, the GNOM ETF saw +$18M in flows, compared to +$93M for PTH.

Which ETF is more volatile: GNOM or PTH?

Over the past year, GNOM had a volatility of 26.78%, while PTH experienced 24.9%.

Which ETF is bigger: GNOM or PTH?

As of July 30, 2026, GNOM holds $81.18 M in assets under management (AUM), while PTH manages $239.95 M.

What sectors do the GNOM and PTH ETFs invest in?

GNOM leans toward sectors like Healthcare. Meanwhile, PTH focuses on Healthcare.

What are the top holdings of the GNOM ETF and PTH ETF?

GNOM top holdings include Guardant Health, Inc., Twist Bioscience Corp. and Illumina, Inc.. PTH holds in its top three: Roivant Sciences Ltd., Praxis Precision Medicines, Inc. and Tango Therapeutics, Inc..

Which ETF is more diversified: GNOM or PTH?

GNOM holds 50 securities with 61.22% of its assets in the top 15. PTH has 57 securities and a top 15 weight of 43.88%.

Continued tightening of the U.S. labor market

Active Trader Report: Use of Leveraged & Inverse ETFs Way Up