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GNOMvsPBEETF Comparison

ETF 1
GNOM

Global X Genomics & Biotechnology ETF - USD

This fund is part of
BioTech & Genomics
-0.12%
Full GNOM fund page
VS
ETF 2
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
-0.12%
Full PBE fund page

Global X Genomics & Biotechnology ETF - USD (GNOM) and Invesco Dynamic Biotechnology & Genome ETF (PBE) belong to the same industry segment: BioTech & Genomics. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.58% for PBE. GNOM is down -0.99% year-to-date (YTD) with -$2M in YTD flows. PBE performs worse with -4.59% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of GNOM and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs PBE performance and flow charts

Performance

-4.0-2.00.02.04.0%Feb 11Feb 19Feb 26Mar 5

Cumulative Flows

-3.5 M-3 M-2.5 M-2 M-1.5 M-1 M-0.5 M0 MFeb 11Feb 19Feb 26Mar 5

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
GNOM
PBE
-2.35%-4.30%
-3.29%-2.36%
-0.99%-4.59%
+29.80%+20.59%
-6.02%+29.95%
-51.80%+5.89%
Flows
GNOM
PBE
--$3M
-$4M+$969K
-$2M+$135K
-$19M-$32M
-$115M-$56M
+$11M-$39M
Volatility and drawdown
3M1Y3Y5Y
Volatility
GNOM
PBE
+23.45%+18.25%
+30.08%+22.16%
+28.53%+20.15%
+33.47%+22.76%
Max drawdown
GNOM
PBE
-10.89%-9.23%
-22.14%-16.18%
-46.50%-22.21%
-72.17%-34.74%
Max drawdown duration
GNOM
PBE
48d63d
113d107d
1031d324d
1714d1540d
Trading data

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GNOM
PBE
Last sale
3/12/2026 at 1:30 PM
$43.61
$76.18
Previous close
03/11/2026
$45.00
$78.26
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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GNOM
PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/12/2026 at 1:30 PM
Live
Closed
GNOM
PBE
Last price
$43.61
$76.18
1D performance
-3.09%
-2.66%
AuM$49.36 M$247.52 M
E/R0.5%0.58%
Characteristics
GNOM
PBE
Management strategyPassivePassive
ProviderGlobal XInvesco
BenchmarkSolactive Genomics IndexDynamic Biotech & Genome Intellidex Index
N° of holdings4630
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateApril 5, 2019June 23, 2005
ESGNoNo
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Exposure

Countries

GNOM
USA
87.04%
Other
12.96%
PBE
USA
94.25%
Other
5.75%

Sectors

GNOM
Health Care
87.95%
Other
12.05%
PBE
Health Care
96.95%
Other
3.05%
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Diversification

GNOM

Total weight of top 15 holdings out of 15

63.95%
PBE

Total weight of top 15 holdings out of 15

61.48%

Top 15 holdings

Data as of January 31, 2026
GNOM
MODERNA INC
6.79%
ARROWHEAD PHARMACEUTICALS INC
6.14%
US74006W2070
5.75%
ILLUMINA
5.64%
GUARDANT HEALTH INC
5.47%
NATERA
4.30%
VERTEX PHARMACEUTICALS
4.08%
BIONTECH SE ADR
4.04%
BIOMARIN PHARMACEUTICAL
3.93%
AVIDITY BIOSCIENCES
3.73%
BIO-TECHNE CORP
3.69%
CRISPR THERAPEUTICS
3.05%
ALNYLAM PHARMACEUTICALS
2.58%
VERACYTE INC/D
2.50%
BRISTOL-MYERS SQUIBB
2.28%
PBE
ILLUMINA
5.91%
GILEAD SCIENCES
5.35%
AMGEN-T
5.09%
REGENERON PHARMACEUTICALS
4.87%
UTD THERAPEUT
4.83%
BIOGEN INC
4.76%
INCYTE
4.70%
ALNYLAM PHARMACEUTICALS
4.05%
AMICUS THERAPEUTICS
3.83%
DYNAVAX TECHNOLOGIES
3.60%
NL0015002SN0
3.05%
ACADIA PHARMACEUTICALS
2.98%
MANNKIND
2.89%
BIO-TECHNE CORP
2.83%
EXELIXIS
2.74%
Frequently asked questions about GNOM and PBE

How have the GNOM and PBE ETFs performed in 2026?

As of March 11, 2026, GNOM is down -0.99% year-to-date (YTD), while PBE has lost -4.59%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or PBE?

Year-to-date, the GNOM ETF saw -$2M in flows, compared to +$135K for PBE.

Which ETF is more volatile: GNOM or PBE?

Over the past year, GNOM had a volatility of 30.08%, while PBE experienced 22.16%.

Which ETF is bigger: GNOM or PBE?

As of March 11, 2026, GNOM holds $49.36 M in assets under management (AUM), while PBE manages $247.52 M.

What sectors do the GNOM and PBE ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the GNOM ETF and PBE ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. PBE holds in its top three: ILLUMINA, GILEAD SCIENCES and AMGEN-T.

Which ETF is more diversified: GNOM or PBE?

GNOM holds 48 securities with 63.95% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 61.48%.

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