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GNOMvsPBEETF Comparison

ETF 1
GNOM

Global X Genomics & Biotechnology ETF

This fund is part of
BioTech & Genomics
+5.19%
VS
ETF 2
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
+5.19%

Global X Genomics & Biotechnology ETF (GNOM) and Invesco Dynamic Biotechnology & Genome ETF (PBE) belong to the same industry segment: BioTech & Genomics. In contrast, PBE's top sector exposures are Healthcare. GNOM is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.59% for PBE. GNOM is up 57.02% year-to-date (YTD) with +$26M in YTD flows. PBE performs worse with 25.32% YTD performance, and +$109M in YTD flows. Run a side-by-side ETF comparison of GNOM and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs PBE performance and flow charts

Performance

-8.0-6.0-4.0-2.00.02.04.0%Sep 28Oct 5Oct 12Oct 19Oct 26

Cumulative Flows

-6 M-4 M-2 M0 M2 M4 M6 MSep 28Oct 5Oct 12Oct 19Oct 26

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Historic performance and flows
Data as of 10/28/2026
1M3MYTD1Y3Y5Y
Perf.
GNOM
PBE
+1.76%+4.58%
+32.26%+11.06%
+57.02%+25.32%
+63.61%+39.95%
+104.36%+96.33%
-15.27%+37.20%
Flows
GNOM
PBE
+$5M-$5M
+$8M+$106M
+$26M+$109M
+$22M+$111M
-$95M+$58M
-$45M+$61M
Volatility and drawdown
3M1Y3Y5Y
Volatility
GNOM
PBE
+43.63%+21.27%
+32.49%+20.03%
+31.04%+20.60%
+34.22%+22.67%
Max drawdown
GNOM
PBE
-10.60%-5.97%
-18.16%-11.70%
-43.10%-22.21%
-68.81%-32.63%
Max drawdown duration
GNOM
PBE
23d46d
145d166d
674d324d
1819d1468d
Trading data

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GNOM
PBE
Last sale
10/29/2026 at 1:30 PM
$72.54
$103.46
Previous close
10/28/2026
$71.51
$101.87
Consolidated volume
10/28/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of September 30, 2026
1-year trailing difference

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GNOM
PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 10/29/2026 at 1:30 PM
Live
Closed
GNOM
PBE
Last price
$72.54
$103.46
1D performance
+1.45%
+1.56%
AuM$113.20 M$438.68 M
E/R0.5%0.59%
Characteristics
GNOM
PBE
Management strategyPassivePassive
ProviderGlobal XInvesco
BenchmarkSolactive Genomics IndexDynamic Biotech & Genome Intellidex Index
N° of holdings-30
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateApril 5, 2019June 23, 2005
ESGNoNo
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Exposure

Countries

GNOM
Data will be available soon
PBE
USA
97.22%
Other
2.78%

Sectors

GNOM
Data will be available soon
PBE
Healthcare
100%
Other
0%
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Diversification

GNOM
Data will be available soon
PBE

Total weight of top 15 holdings out of 15

63.67%

Top 15 holdings

Data as of January 1, 1970
GNOM
Data will be available soon
PBE
CareDx, Inc.
5.49%
Amgen, Inc.
5.38%
Regeneron Pharmaceuticals, Inc.
5.26%
Vertex Pharmaceuticals, Inc.
5.21%
Royalty Pharma Plc
4.76%
Biogen, Inc.
4.75%
Gilead Sciences, Inc.
4.61%
United Therapeutics Corp.
3.77%
Omeros Corp.
3.73%
Repligen Corp.
3.57%
Illumina, Inc.
3.54%
Halozyme Therapeutics, Inc.
3.51%
Bio-Techne Corp.
3.41%
Protagonist Therapeutics, Inc.
3.37%
Alnylam Pharmaceuticals, Inc.
3.31%
Frequently asked questions about GNOM and PBE

How have the GNOM and PBE ETFs performed in 2026?

As of October 28, 2026, GNOM is up 57.02% year-to-date (YTD), while PBE has returned 25.32%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or PBE?

Year-to-date, the GNOM ETF saw +$26M in flows, compared to +$109M for PBE.

Which ETF is more volatile: GNOM or PBE?

Over the past year, GNOM had a volatility of 32.49%, while PBE experienced 20.03%.

Which ETF is bigger: GNOM or PBE?

As of October 28, 2026, GNOM holds $113.20 M in assets under management (AUM), while PBE manages $438.68 M.

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