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GNOMvsPBEETF Comparison

ETF 1

GNOM

Global X Genomics & Biotechnology ETF - USD

This fund is part of

BioTech & Genomics

-0.67%

Full GNOM fund page

VS

ETF 2

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

-0.67%

Full PBE fund page

Global X Genomics & Biotechnology ETF - USD (GNOM) and Invesco Dynamic Biotechnology & Genome ETF (PBE) belong to the same industry segment: BioTech & Genomics. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.58% for PBE. GNOM is up 0.74% year-to-date (YTD) with -$602K in YTD flows. PBE performs worse with -2.66% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of GNOM and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs PBE performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	GNOM PBE	+7.67%+4.27%	-7.03%-3.98%	+0.74%-2.66%	+41.51%+32.11%	-6.56%+28.24%	-50.60%+3.38%
Flows	GNOM PBE	-$829K+$2M	+$1M-$6M	-$602K-$2M	-$14M-$30M	-$120M-$58M	+$1M-$43M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	GNOM PBE	+28.47%+19.57%	+27.16%+19.83%	+28.79%+20.15%	+33.22%+22.54%
Max drawdown	GNOM PBE	-16.08%-9.36%	-18.16%-11.70%	-46.50%-22.21%	-72.17%-34.74%
Max drawdown duration	GNOM PBE	88d75d	92d107d	1075d324d	1758d1540d

Trading data

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	GNOM	PBE
Last sale 4/27/2026 at 1:30 PM	$45.43	$79.78
Previous close 04/24/2026	$45.97	$79.82
Consolidated volume 04/24/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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	GNOM	PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/27/2026 at 1:30 PM

Live

Closed

	GNOM	PBE
Last price	$45.43	$79.78
1D performance	-1.17%	-0.05%
AuM	$51.60 M	$249.88 M
E/R	0.5%	0.58%

Characteristics

	GNOM	PBE
Management strategy	Passive	Passive
Provider	Global X	Invesco
Benchmark	Solactive Genomics Index	Dynamic Biotech & Genome Intellidex Index
N° of holdings	45	30
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	April 5, 2019	June 23, 2005
ESG	No	No

More GNOM data on Trackinsight

More PBE data on Trackinsight

Exposure

Countries

GNOM

USA

87.57%

Other

12.43%

PBE

USA

92.18%

Other

7.82%

Sectors

GNOM

Health Care

88.49%

Other

11.51%

PBE

Health Care

97.59%

Other

2.41%

Diversification

GNOM

Total weight of top 15 holdings out of 15

66.21%

PBE

Total weight of top 15 holdings out of 15

63.66%

Top 15 holdings

Data as of March 31, 2026

GNOM

MODERNA INC

8.48%

ARROWHEAD PHARMACEUTICALS INC

6.21%

US74006W2070

6.13%

ILLUMINA

5.52%

GUARDANT HEALTH INC

5.18%

VERTEX PHARMACEUTICALS

4.61%

BIOMARIN PHARMACEUTICAL

4.59%

NATERA

4.21%

BIO-TECHNE CORP

3.64%

BIONTECH SE ADR

3.58%

CRISPR THERAPEUTICS

3.08%

BRISTOL-MYERS SQUIBB

3.05%

ALNYLAM PHARMACEUTICALS

2.85%

TWIST BIOSCIENCE CORP

2.54%

ASTRAZENECA

2.53%

PBE

UTD THERAPEUT

6.05%

ILLUMINA

5.24%

REGENERON PHARMACEUTICALS

5.23%

ALNYLAM PHARMACEUTICALS

5.22%

BIOGEN INC

5.16%

AMGEN-T

4.99%

GILEAD SCIENCES

4.98%

INCYTE

4.89%

BIOCRYST PHARMACEUTICALS

3.66%

PROTAGONIST THERAPEUTICS INC

3.38%

TG THERAPEUTICS

3.11%

ROYALTY PHARMA

3.05%

NEUROCRINE BIOSCIENCES

2.93%

CATALYST PHARMACEUTICALS INC

2.89%

PTC THERAPEUTI/D

2.86%

Frequently asked questions about GNOM and PBE

How have the GNOM and PBE ETFs performed in 2026?

As of April 24, 2026, GNOM is up 0.74% year-to-date (YTD), while PBE has lost -2.66%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or PBE?

Year-to-date, the GNOM ETF saw -$602K in flows, compared to -$2M for PBE.

Which ETF is more volatile: GNOM or PBE?

Over the past year, GNOM had a volatility of 27.16%, while PBE experienced 19.83%.

Which ETF is bigger: GNOM or PBE?

As of April 24, 2026, GNOM holds $51.60 M in assets under management (AUM), while PBE manages $249.88 M.

What sectors do the GNOM and PBE ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the GNOM ETF and PBE ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. PBE holds in its top three: UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS.

GNOMvsPBEETF Comparison

Global X Genomics & Biotechnology ETF - USD

Invesco Dynamic Biotechnology & Genome ETF

GNOM vs PBE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the GNOM and PBE ETFs performed in 2026?

As of April 24, 2026, GNOM is up 0.74% year-to-date (YTD), while PBE has lost -2.66%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or PBE?

Year-to-date, the GNOM ETF saw -$602K in flows, compared to -$2M for PBE.

Which ETF is more volatile: GNOM or PBE?

Over the past year, GNOM had a volatility of 27.16%, while PBE experienced 19.83%.

Which ETF is bigger: GNOM or PBE?

As of April 24, 2026, GNOM holds $51.60 M in assets under management (AUM), while PBE manages $249.88 M.

What sectors do the GNOM and PBE ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the GNOM ETF and PBE ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. PBE holds in its top three: UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS.

Which ETF is more diversified: GNOM or PBE?

GNOM holds 47 securities with 66.21% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 63.66%.

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