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GNOMvsIBBQETF Comparison

ETF 1
GNOM

Global X Genomics & Biotechnology ETF - USD

This fund is part of
BioTech & Genomics
-0.67%
VS
ETF 2
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-1.08%

Global X Genomics & Biotechnology ETF - USD (GNOM) belongs to the BioTech & Genomics segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.19% for IBBQ. GNOM is up 0.74% year-to-date (YTD) with -$602K in YTD flows. IBBQ performs better with 3.49% YTD performance, and +$290K in YTD flows. Run a side-by-side ETF comparison of GNOM and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs IBBQ performance and flow charts

Performance

0510%Mar 24Mar 31Apr 8Apr 15Apr 22

Cumulative Flows

-8 M-6 M-4 M-2 M0 MMar 24Mar 31Apr 8Apr 15Apr 22

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Historic performance and flows
Data as of 04/24/2026
1M3MYTD1Y3Y5Y
Perf.
GNOM
IBBQ
+7.67%+5.67%
-7.03%-0.91%
+0.74%+3.49%
+41.51%+41.67%
-6.56%+41.72%
-50.60%n/a
Flows
GNOM
IBBQ
-$829K-$8M
+$1M-$9M
-$602K+$290K
-$14M+$14M
-$120M+$34M
+$1M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
GNOM
IBBQ
+28.47%+22.23%
+27.16%+21.05%
+28.79%+19.62%
+33.22%n/a
Max drawdown
GNOM
IBBQ
-16.08%-8.38%
-18.16%-8.39%
-46.50%-23.78%
-72.17%n/a
Max drawdown duration
GNOM
IBBQ
88d48d
92d33d
1075d375d
1758dn/a
Trading data

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GNOM
IBBQ
Last sale
4/24/2026 at 7:55 PM
$45.97
$29.40
Previous close
04/24/2026
$46.16
$29.34
Consolidated volume
04/24/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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GNOM
IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/24/2026 at 7:55 PM
Live
Closed
GNOM
IBBQ
Last price
$45.97
$29.40
1D performance
-0.42%
+0.21%
AuM$51.60 M$66.29 M
E/R0.5%0.19%
Characteristics
GNOM
IBBQ
Management strategyPassivePassive
ProviderGlobal XInvesco
BenchmarkSolactive Genomics IndexNASDAQ Biotechnology Index
N° of holdings45192
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateApril 5, 2019June 9, 2021
ESGNoNo
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Exposure

Countries

GNOM
USA
87.57%
Other
12.43%
IBBQ
USA
92.77%
Other
7.23%

Sectors

GNOM
Health Care
88.49%
Other
11.51%
IBBQ
Health Care
85.9%
Other
14.1%
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Diversification

GNOM

Total weight of top 15 holdings out of 15

66.21%
IBBQ

Total weight of top 15 holdings out of 15

51.37%

Top 15 holdings

Data as of March 31, 2026
GNOM
MODERNA INC
8.48%
ARROWHEAD PHARMACEUTICALS INC
6.21%
US74006W2070
6.13%
ILLUMINA
5.52%
GUARDANT HEALTH INC
5.18%
VERTEX PHARMACEUTICALS
4.61%
BIOMARIN PHARMACEUTICAL
4.59%
NATERA
4.21%
BIO-TECHNE CORP
3.64%
BIONTECH SE ADR
3.58%
CRISPR THERAPEUTICS
3.08%
BRISTOL-MYERS SQUIBB
3.05%
ALNYLAM PHARMACEUTICALS
2.85%
TWIST BIOSCIENCE CORP
2.54%
ASTRAZENECA
2.53%
IBBQ
GILEAD SCIENCES
7.85%
AMGEN-T
7.82%
VERTEX PHARMACEUTICALS
7.59%
REGENERON PHARMACEUTICALS
6.48%
ALNYLAM PHARMACEUTICALS
3.56%
INSMED
2.65%
BIOGEN INC
2.28%
UTD THERAPEUT
1.94%
ROYALTY PHARMA
1.68%
US04016X1019
1.66%
MODERNA INC
1.66%
ROIVANT SCIENCES LTD
1.61%
REVOLUTION MEDICINES INC
1.55%
ILLUMINA
1.52%
INCYTE
1.52%
Frequently asked questions about GNOM and IBBQ

How have the GNOM and IBBQ ETFs performed in 2026?

As of April 24, 2026, GNOM is up 0.74% year-to-date (YTD), while IBBQ has returned 3.49%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or IBBQ?

Year-to-date, the GNOM ETF saw -$602K in flows, compared to +$290K for IBBQ.

Which ETF is more volatile: GNOM or IBBQ?

Over the past year, GNOM had a volatility of 27.16%, while IBBQ experienced 21.05%.

Which ETF is bigger: GNOM or IBBQ?

As of April 24, 2026, GNOM holds $51.60 M in assets under management (AUM), while IBBQ manages $66.29 M.

What sectors do the GNOM and IBBQ ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the GNOM ETF and IBBQ ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. IBBQ holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.

Which ETF is more diversified: GNOM or IBBQ?

GNOM holds 47 securities with 66.21% of its assets in the top 15. IBBQ has 256 securities and a top 15 weight of 51.37%.

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