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GNOMvsIBBQETF Comparison

ETF 1
GNOM

Global X Genomics & Biotechnology ETF - USD

This fund is part of
BioTech & Genomics
-0.26%
Full GNOM fund page
VS
ETF 2
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-0.51%
Full IBBQ fund page

Global X Genomics & Biotechnology ETF - USD (GNOM) belongs to the BioTech & Genomics segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.19% for IBBQ. GNOM is down -0.14% year-to-date (YTD) with -$2M in YTD flows. IBBQ performs better with 4.22% YTD performance, and +$8M in YTD flows. Run a side-by-side ETF comparison of GNOM and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs IBBQ performance and flow charts

Performance

-2.0-1.00.01.02.03.0%Feb 10Feb 18Feb 25Mar 4

Cumulative Flows

0 M0.5 M1 M1.5 M2 MFeb 10Feb 18Feb 25Mar 4

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Historic performance and flows
Data as of 03/10/2026
1M3MYTD1Y3Y5Y
Perf.
GNOM
IBBQ
-1.95%+0.87%
-2.77%+4.73%
-0.14%+4.22%
+31.18%+33.45%
-2.20%+56.06%
-49.04%n/a
Flows
GNOM
IBBQ
-+$2M
-$4M+$13M
-$2M+$8M
-$19M+$22M
-$115M+$41M
+$13M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
GNOM
IBBQ
+23.39%+19.87%
+30.06%+23.00%
+28.58%+19.31%
+33.54%n/a
Max drawdown
GNOM
IBBQ
-10.49%-4.51%
-22.14%-17.24%
-46.50%-23.78%
-72.17%n/a
Max drawdown duration
GNOM
IBBQ
47d14d
113d127d
1030d375d
1713dn/a
Trading data

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GNOM
IBBQ
Last sale
3/11/2026 at 1:30 PM
$45.00
$29.39
Previous close
03/10/2026
$45.33
$29.56
Consolidated volume
03/10/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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GNOM
IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/11/2026 at 1:30 PM
Live
Closed
GNOM
IBBQ
Last price
$45.00
$29.39
1D performance
-0.74%
-0.58%
AuM$49.78 M$74.53 M
E/R0.5%0.19%
Characteristics
GNOM
IBBQ
Management strategyPassivePassive
ProviderGlobal XInvesco
BenchmarkSolactive Genomics IndexNASDAQ Biotechnology Index
N° of holdings46196
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateApril 5, 2019June 9, 2021
ESGNoNo
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Exposure

Countries

GNOM
USA
87.04%
Other
12.96%
IBBQ
USA
93.84%
Other
6.16%

Sectors

GNOM
Health Care
87.95%
Other
12.05%
IBBQ
Health Care
85.82%
Other
14.18%
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Diversification

GNOM

Total weight of top 15 holdings out of 15

63.95%
IBBQ

Total weight of top 15 holdings out of 15

52.08%

Top 15 holdings

Data as of January 31, 2026
GNOM
MODERNA INC
6.79%
ARROWHEAD PHARMACEUTICALS INC
6.14%
US74006W2070
5.75%
ILLUMINA
5.64%
GUARDANT HEALTH INC
5.47%
NATERA
4.30%
VERTEX PHARMACEUTICALS
4.08%
BIONTECH SE ADR
4.04%
BIOMARIN PHARMACEUTICAL
3.93%
AVIDITY BIOSCIENCES
3.73%
BIO-TECHNE CORP
3.69%
CRISPR THERAPEUTICS
3.05%
ALNYLAM PHARMACEUTICALS
2.58%
VERACYTE INC/D
2.50%
BRISTOL-MYERS SQUIBB
2.28%
IBBQ
VERTEX PHARMACEUTICALS
8.96%
GILEAD SCIENCES
8.92%
AMGEN-T
8.25%
REGENERON PHARMACEUTICALS
5.90%
ALNYLAM PHARMACEUTICALS
3.58%
INSMED
2.55%
BIOGEN INC
1.90%
US04016X1019
1.82%
ILLUMINA
1.75%
UTD THERAPEUT
1.53%
INCYTE
1.51%
REVOLUTION MEDICINES INC
1.42%
MODERNA INC
1.41%
ROYALTY PHARMA
1.30%
MEDPACE HOLDINGS INC
1.27%
Frequently asked questions about GNOM and IBBQ

How have the GNOM and IBBQ ETFs performed in 2026?

As of March 10, 2026, GNOM is down -0.14% year-to-date (YTD), while IBBQ has returned 4.22%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or IBBQ?

Year-to-date, the GNOM ETF saw -$2M in flows, compared to +$8M for IBBQ.

Which ETF is more volatile: GNOM or IBBQ?

Over the past year, GNOM had a volatility of 30.06%, while IBBQ experienced 23%.

Which ETF is bigger: GNOM or IBBQ?

As of March 10, 2026, GNOM holds $49.78 M in assets under management (AUM), while IBBQ manages $74.53 M.

What sectors do the GNOM and IBBQ ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the GNOM ETF and IBBQ ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. IBBQ holds in its top three: VERTEX PHARMACEUTICALS, GILEAD SCIENCES and AMGEN-T.

Which ETF is more diversified: GNOM or IBBQ?

GNOM holds 48 securities with 63.95% of its assets in the top 15. IBBQ has 262 securities and a top 15 weight of 52.08%.

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