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GNOMvsHELXETF Comparison

ETF 1
GNOM

Global X Genomics & Biotechnology ETF

This fund is part of
BioTech & Genomics
+5.19%
VS
ETF 2
HELX

Franklin Genomic Advancements ETF

This fund is part of
BioTech & Genomics
+5.19%

Global X Genomics & Biotechnology ETF (GNOM) and Franklin Genomic Advancements ETF (HELX) belong to the same industry segment: BioTech & Genomics. In contrast, HELX's top sector exposures are Healthcare, Non-Energy Materials and Technology. Both GNOM and HELX have the same Total Expense Ratio (TER) of 0.5%. GNOM is up 57.02% year-to-date (YTD) with +$26M in YTD flows. HELX performs worse with 25.31% YTD performance, and +$8M in YTD flows. Run a side-by-side ETF comparison of GNOM and HELX below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs HELX performance and flow charts

Performance

-8.0-6.0-4.0-2.00.02.0%Sep 28Oct 5Oct 12Oct 19Oct 26

Cumulative Flows

-2 M0 M2 M4 M6 MSep 28Oct 5Oct 12Oct 19Oct 26

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Historic performance and flows
Data as of 10/28/2026
1M3MYTD1Y3Y5Y
Perf.
GNOM
HELX
+1.76%+2.45%
+32.26%+16.28%
+57.02%+25.31%
+63.61%+32.93%
+104.36%+79.37%
-15.27%-14.67%
Flows
GNOM
HELX
+$5M+$2M
+$8M+$2M
+$26M+$8M
+$22M+$8M
-$95M+$17M
-$45M+$8M
Volatility and drawdown
3M1Y3Y5Y
Volatility
GNOM
HELX
+43.63%+27.48%
+32.49%+24.08%
+31.04%+21.93%
+34.22%+23.66%
Max drawdown
GNOM
HELX
-10.60%-8.93%
-18.16%-17.89%
-43.10%-29.16%
-68.81%-55.27%
Max drawdown duration
GNOM
HELX
23d22d
145d206d
674d458d
1819d1821d
Trading data

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GNOM
HELX
Last sale
10/29/2026 at 1:30 PM
$72.54
$46.01
Previous close
10/28/2026
$71.51
$45.47
Consolidated volume
10/28/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of September 30, 2026
1-year trailing difference

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HELX
is actively managed and doesn’t replicate an index

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GNOM
HELX
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 10/29/2026 at 1:30 PM
Live
Closed
GNOM
HELX
Last price
$72.54
$46.01
1D performance
+1.45%
+1.18%
AuM$113.20 M$36.38 M
E/R0.5%0.5%
Characteristics
GNOM
HELX
Management strategyPassiveActive
ProviderGlobal XFranklin Templeton
BenchmarkSolactive Genomics Index-
N° of holdings-66
Asset classEquities-
Trailing 12m distribution yield
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Inception dateApril 5, 2019February 25, 2020
ESGNoNo
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Exposure

Countries

GNOM
Data will be available soon
HELX
USA
89.58%
Other
10.42%

Sectors

GNOM
Data will be available soon
HELX
Healthcare
96.71%
Other
3.29%
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Diversification

GNOM
Data will be available soon
HELX

Total weight of top 15 holdings out of 15

60.55%

Top 15 holdings

Data as of January 1, 1970
GNOM
Data will be available soon
HELX
Guardant Health, Inc.
9.55%
Natera, Inc.
8.57%
Krystal Biotech, Inc.
5.64%
Adaptive Biotechnologies Corp.
4.49%
Ligand Pharmaceuticals, Inc.
4.22%
Twist Bioscience Corp.
4.19%
BridgeBio Pharma, Inc.
3.44%
United Therapeutics Corp.
3.08%
Travere Therapeutics, Inc.
2.99%
Vertex Pharmaceuticals, Inc.
2.78%
Medpace Holdings, Inc.
2.69%
Corteva, Inc.
2.50%
Eli Lilly & Co.
2.31%
Regeneron Pharmaceuticals, Inc.
2.15%
Repligen Corp.
1.97%
Frequently asked questions about GNOM and HELX

How have the GNOM and HELX ETFs performed in 2026?

As of October 28, 2026, GNOM is up 57.02% year-to-date (YTD), while HELX has returned 25.31%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or HELX?

Year-to-date, the GNOM ETF saw +$26M in flows, compared to +$8M for HELX.

Which ETF is more volatile: GNOM or HELX?

Over the past year, GNOM had a volatility of 32.49%, while HELX experienced 24.08%.

Which ETF is bigger: GNOM or HELX?

As of October 28, 2026, GNOM holds $113.20 M in assets under management (AUM), while HELX manages $36.38 M.

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