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GNOMvsFMEDETF Comparison

ETF 1
GNOM

Global X Genomics & Biotechnology ETF

This fund is part of
BioTech & Genomics
+3.75%
VS
ETF 2
FMED

Fidelity Disruptive Medicine ETF

This fund is part of
Multiple Trends
+2.51%

Global X Genomics & Biotechnology ETF (GNOM) belongs to the BioTech & Genomics segment. Fidelity Disruptive Medicine ETF (FMED) is part of the Multiple Trends segment. Both ETFs have the same top 3 sector exposures: and Health Care. Both GNOM and FMED have the same Total Expense Ratio (TER) of 0.5%. GNOM is up 10.2% year-to-date (YTD) with +$4M in YTD flows. FMED performs worse with -4.62% YTD performance, and -$17M in YTD flows. Run a side-by-side ETF comparison of GNOM and FMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs FMED performance and flow charts

Performance

0510%May 15May 22Jun 1Jun 8Jun 15

Cumulative Flows

-2 M-1 M0 M1 M2 M3 M4 MMay 15May 22Jun 1Jun 8Jun 15

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Historic performance and flows
Data as of 06/15/2026
1M3MYTD1Y3Y5Y
Perf.
GNOM
FMED
+13.00%+7.29%
+14.76%+5.03%
+10.20%-4.62%
+54.07%+8.80%
-1.12%+1.73%
-44.29%n/a
Flows
GNOM
FMED
+$4M-$2M
+$6M-$17M
+$4M-$17M
-$4M-$14M
-$104M-$3M
+$5M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
GNOM
FMED
+31.68%+23.76%
+26.60%+18.87%
+28.96%+18.24%
+33.27%n/a
Max drawdown
GNOM
FMED
-7.88%-9.15%
-18.16%-17.78%
-45.66%-21.76%
-72.17%n/a
Max drawdown duration
GNOM
FMED
36d57d
144d197d
1096d218d
1810dn/a
Trading data

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GNOM
FMED
Last sale
6/16/2026 at 2:04 PM
$50.22
$25.51
Previous close
06/15/2026
$50.10
$24.96
Consolidated volume
06/15/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of May 29, 2026
1-year trailing difference

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FMED
is actively managed and doesn’t replicate an index

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GNOM
FMED
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 6/16/2026 at 2:04 PM
Live
Closed
GNOM
FMED
Last price
$50.22
$25.51
1D performance
+0.24%
+2.21%
AuM$60.96 M$41.96 M
E/R0.5%0.5%
Characteristics
GNOM
FMED
Management strategyPassiveActive
ProviderGlobal XFidelity
BenchmarkSolactive Genomics Index-
N° of holdings4550
Asset classEquities-
Trailing 12m distribution yield
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Inception dateApril 5, 2019June 12, 2023
ESGNoNo
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Exposure

Countries

GNOM
USA
88%
Other
12%
FMED
USA
87.03%
Other
12.97%

Sectors

GNOM
Health Care
88.52%
Other
11.48%
FMED
Health Care
80.26%
Other
19.74%
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Diversification

GNOM

Total weight of top 15 holdings out of 15

66.44%
FMED

Total weight of top 15 holdings out of 15

42.54%

Top 15 holdings

Data as of April 30, 2026
GNOM
MODERNA INC
7.59%
ARROWHEAD PHARMACEUTICALS INC
7.18%
US74006W2070
6.77%
ILLUMINA
5.19%
GUARDANT HEALTH INC
4.73%
BIOMARIN PHARMACEUTICAL
4.29%
VERTEX PHARMACEUTICALS
4.16%
NATERA
4.14%
BIONTECH SE ADR
4.03%
BIO-TECHNE CORP
3.44%
CRISPR THERAPEUTICS
3.32%
TWIST BIOSCIENCE CORP
3.14%
LEGEND BIOTECH
2.91%
NL0015002SN0
2.77%
BRISTOL-MYERS SQUIBB
2.77%
FMED
DANAHER
3.81%
INTUITIVE SURGICAL
3.70%
UCB
3.44%
COGENT BIOSCIENCES
3.36%
ALNYLAM PHARMACEUTICALS
3.20%
LIFESTANCE HEALTH GROUP
2.85%
US04016X1019
2.75%
BIO-TECHNE CORP
2.69%
INSMED
2.57%
EDWARDS LIFESCIENCES
2.49%
MODERNA INC
2.45%
UNITEDHEALTH GRP
2.35%
VAXCYTE
2.31%
US1421521071
2.30%
US42238D1072
2.28%
Frequently asked questions about GNOM and FMED

How have the GNOM and FMED ETFs performed in 2026?

As of June 15, 2026, GNOM is up 10.2% year-to-date (YTD), while FMED has lost -4.62%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or FMED?

Year-to-date, the GNOM ETF saw +$4M in flows, compared to -$17M for FMED.

Which ETF is more volatile: GNOM or FMED?

Over the past year, GNOM had a volatility of 26.6%, while FMED experienced 18.87%.

Which ETF is bigger: GNOM or FMED?

As of June 15, 2026, GNOM holds $60.96 M in assets under management (AUM), while FMED manages $41.96 M.

What sectors do the GNOM and FMED ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, FMED focuses on Health Care.

What are the top holdings of the GNOM ETF and FMED ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. FMED holds in its top three: DANAHER, INTUITIVE SURGICAL and UCB.

Which ETF is more diversified: GNOM or FMED?

GNOM holds 49 securities with 66.44% of its assets in the top 15. FMED has 68 securities and a top 15 weight of 42.54%.

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