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GNOMvsFMEDETF Comparison

ETF 1

GNOM

Global X Genomics & Biotechnology ETF

This fund is part of

BioTech & Genomics

+3.8%

Full GNOM fund page

VS

ETF 2

FMED

Fidelity Disruptive Medicine ETF

This fund is part of

Multiple Trends

+5.9%

Full FMED fund page

Global X Genomics & Biotechnology ETF (GNOM) belongs to the BioTech & Genomics segment. Fidelity Disruptive Medicine ETF (FMED) is part of the Multiple Trends segment. GNOM's top 3 sector exposures are Healthcare and Industrials. In contrast, FMED's top sector exposures are Healthcare Both GNOM and FMED have the same Total Expense Ratio (TER) of 0.5%. GNOM is up 21.83% year-to-date (YTD) with +$18M in YTD flows. FMED performs worse with 5.96% YTD performance, and -$17M in YTD flows. Run a side-by-side ETF comparison of GNOM and FMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs FMED performance and flow charts

Performance

Cumulative Flows

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Data Services

Historic performance and flows

Data as of 07/30/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	GNOM FMED	-2.19%+0.45%	+22.58%+15.63%	+21.83%+5.96%	+58.30%+19.83%	+14.80%+13.57%	-38.54%n/a
Flows	GNOM FMED	+$7M-	+$19M-$17M	+$18M-$17M	+$13M-$14M	-$95M-$3M	-$862K-

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	GNOM FMED	+28.16%+21.64%	+26.78%+19.54%	+29.11%+18.58%	+33.32%n/a
Max drawdown	GNOM FMED	-8.57%-5.92%	-18.16%-17.78%	-43.10%-21.33%	-72.01%n/a
Max drawdown duration	GNOM FMED	24d21d	145d212d	674d210d	1792dn/a

Trading data

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	GNOM	FMED
Last sale 7/31/2026 at 3:22 PM	$53.88
Previous close 07/30/2026	$55.39
Consolidated volume 07/30/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of June 30, 2026

1-year trailing difference

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FMED

is actively managed and doesn’t replicate an index

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	GNOM	FMED
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 7/31/2026 at 3:22 PM

Live

Closed

	GNOM	FMED
Last price	$53.88	–
1D performance	-2.73%	–
AuM	$81.18 M	$46.62 M
E/R	0.5%	0.5%

Characteristics

	GNOM	FMED
Management strategy	Passive	Active
Provider	Global X	Fidelity
Benchmark	Solactive Genomics Index	-
N° of holdings	50	69
Asset class	Equities	-
Trailing 12m distribution yield	Join	Join
Inception date	April 5, 2019	June 12, 2023
ESG	No	No

More GNOM data on Trackinsight

More FMED data on Trackinsight

Exposure

Countries

GNOM

USA

84.1%

Other

15.9%

FMED

USA

83.89%

Other

16.11%

Sectors

GNOM

Healthcare

99.75%

Other

0.25%

FMED

Healthcare

100%

Other

-0%

Diversification

GNOM

Total weight of top 15 holdings out of 15

61.22%

FMED

Total weight of top 15 holdings out of 15

41.87%

Top 15 holdings

Data as of June 30, 2026

GNOM

Guardant Health, Inc.

5.78%

Twist Bioscience Corp.

5.09%

Illumina, Inc.

4.67%

Natera, Inc.

4.41%

Moderna, Inc.

4.22%

Veracyte, Inc.

4.12%

Bio-Techne Corp.

4.08%

Vertex Pharmaceuticals, Inc.

3.85%

Legend Biotech Corp.

3.82%

10X Genomics, Inc.

3.70%

Arrowhead Pharmaceuticals, Inc.

3.67%

BioMarin Pharmaceutical, Inc.

3.59%

Praxis Precision Medicines, Inc.

3.50%

CRISPR Therapeutics AG

3.36%

QIAGEN NV

3.35%

FMED

Lifestance Health Group, Inc.

5.11%

10X Genomics, Inc.

3.56%

Danaher Corp.

3.29%

UCB SA

3.09%

Cogent Biosciences, Inc.

2.79%

Bio-Techne Corp.

2.76%

Moderna, Inc.

2.69%

Intuitive Surgical, Inc.

2.49%

argenx SE

2.43%

Alnylam Pharmaceuticals, Inc.

2.41%

Kymera Therapeutics, Inc.

2.36%

UnitedHealth Group, Inc.

2.27%

Thermo Fisher Scientific, Inc.

2.24%

Ascendis Pharma A/S

2.21%

Legend Biotech Corp.

2.17%

Frequently asked questions about GNOM and FMED

How have the GNOM and FMED ETFs performed in 2026?

As of July 30, 2026, GNOM is up 21.83% year-to-date (YTD), while FMED has returned 5.96%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or FMED?

Year-to-date, the GNOM ETF saw +$18M in flows, compared to -$17M for FMED.

Which ETF is more volatile: GNOM or FMED?

Over the past year, GNOM had a volatility of 26.78%, while FMED experienced 19.54%.

Which ETF is bigger: GNOM or FMED?

As of July 30, 2026, GNOM holds $81.18 M in assets under management (AUM), while FMED manages $46.62 M.

What sectors do the GNOM and FMED ETFs invest in?

GNOM leans toward sectors like Healthcare. Meanwhile, FMED focuses on Healthcare.

What are the top holdings of the GNOM ETF and FMED ETF?

GNOM top holdings include Guardant Health, Inc., Twist Bioscience Corp. and Illumina, Inc.. FMED holds in its top three: Lifestance Health Group, Inc., 10X Genomics, Inc. and Danaher Corp..

GNOMvsFMEDETF Comparison

Global X Genomics & Biotechnology ETF

Fidelity Disruptive Medicine ETF

GNOM vs FMED performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the GNOM and FMED ETFs performed in 2026?

As of July 30, 2026, GNOM is up 21.83% year-to-date (YTD), while FMED has returned 5.96%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or FMED?

Year-to-date, the GNOM ETF saw +$18M in flows, compared to -$17M for FMED.

Which ETF is more volatile: GNOM or FMED?

Over the past year, GNOM had a volatility of 26.78%, while FMED experienced 19.54%.

Which ETF is bigger: GNOM or FMED?

As of July 30, 2026, GNOM holds $81.18 M in assets under management (AUM), while FMED manages $46.62 M.

What sectors do the GNOM and FMED ETFs invest in?

GNOM leans toward sectors like Healthcare. Meanwhile, FMED focuses on Healthcare.

What are the top holdings of the GNOM ETF and FMED ETF?

GNOM top holdings include Guardant Health, Inc., Twist Bioscience Corp. and Illumina, Inc.. FMED holds in its top three: Lifestance Health Group, Inc., 10X Genomics, Inc. and Danaher Corp..

Which ETF is more diversified: GNOM or FMED?

GNOM holds 50 securities with 61.22% of its assets in the top 15. FMED has 69 securities and a top 15 weight of 41.87%.

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