GNOMvsFBTETF Comparison
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Global X Genomics & Biotechnology ETF - USD (GNOM) belongs to the BioTech & Genomics segment. First Trust NYSE Arca Biotechnology Index Fund ETF (FBT) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.54% for FBT. GNOM is up 0.74% year-to-date (YTD) with -$602K in YTD flows. FBT performs worse with -0.93% YTD performance, and +$1.07B in YTD flows. Run a side-by-side ETF comparison of GNOM and FBT below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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GNOM vs FBT performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | GNOM FBT | +7.67%+6.35% | -7.03%-6.86% | +0.74%-0.93% | +41.51%+29.41% | -6.56%+31.14% | -50.60%+24.73% |
| Flows | GNOM FBT | -$829K-$20M | +$1M+$101M | -$602K+$1.07B | -$14M+$1.08B | -$120M+$617M | +$1M+$289M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | GNOM FBT | +28.47%+23.37% | +27.16%+21.80% | +28.79%+20.22% | +33.22%+21.89% |
| Max drawdown | GNOM FBT | -16.08%-13.39% | -18.16%-14.27% | -46.50%-19.92% | -72.17%-29.98% |
| Max drawdown duration | GNOM FBT | 88d87d | 92d91d | 1075d237d | 1758d1243d |
Trading data
GNOM | FBT | |
Last sale 4/27/2026 at 1:30 PM | $45.43 | $204.75 |
| Previous close 04/24/2026 | $45.97 | $204.04 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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GNOM | FBT | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
GNOM | FBT | |
|---|---|---|
| Last price | $45.43 | $204.75 |
| 1D performance | -1.17% | +0.35% |
| AuM | $51.60 M | $2.31 B |
| E/R | 0.5% | 0.54% |
Characteristics
GNOM | FBT | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Global X | First Trust |
| Benchmark | Solactive Genomics Index | NYSE Arca Biotechnology Index |
| N° of holdings | 45 | 28 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 5, 2019 | June 19, 2006 |
| ESG | No | No |
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Exposure
Countries
GNOM
USA
87.57%
Other
12.43%
FBT
USA
95.76%
Other
4.24%
Sectors
GNOM
Health Care
88.49%
Other
11.51%
FBT
Health Care
90.59%
Other
9.41%
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Diversification
GNOM
Total weight of top 15 holdings out of 15
66.21%
FBT
Total weight of top 15 holdings out of 15
56.66%
Top 15 holdings
Data as of March 31, 2026
GNOM
MODERNA INC
8.48%
ARROWHEAD PHARMACEUTICALS INC
6.21%
US74006W2070
6.13%
ILLUMINA
5.52%
GUARDANT HEALTH INC
5.18%
VERTEX PHARMACEUTICALS
4.61%
BIOMARIN PHARMACEUTICAL
4.59%
NATERA
4.21%
BIO-TECHNE CORP
3.64%
BIONTECH SE ADR
3.58%
CRISPR THERAPEUTICS
3.08%
BRISTOL-MYERS SQUIBB
3.05%
ALNYLAM PHARMACEUTICALS
2.85%
TWIST BIOSCIENCE CORP
2.54%
ASTRAZENECA
2.53%
FBT
MODERNA INC
5.14%
ALKERMES
4.16%
UTD THERAPEUT
4.15%
GILEAD SCIENCES
4.08%
CORCEPT THERAPEUTICS
3.94%
AXSOME THERA CMN STK
3.91%
AMGEN-T
3.81%
EXELIXIS
3.52%
KRYSTAL BIOTECH INC
3.49%
BIOGEN INC
3.45%
REGENERON PHARMACEUTICALS
3.44%
NEUROCRINE BIOSCIENCES
3.44%
BIOMARIN PHARMACEUTICAL
3.42%
VERTEX PHARMACEUTICALS
3.39%
US04016X1019
3.32%
Frequently asked questions about GNOM and FBT
How have the GNOM and FBT ETFs performed in 2026?
As of April 24, 2026, GNOM is up 0.74% year-to-date (YTD), while FBT has lost -0.93%. That puts GNOM better performer ahead so far this year.
Which ETF is attracting more investor money: GNOM or FBT?
Year-to-date, the GNOM ETF saw -$602K in flows, compared to +$1.07B for FBT.
Which ETF is more volatile: GNOM or FBT?
Over the past year, GNOM had a volatility of 27.16%, while FBT experienced 21.8%.
Which ETF is bigger: GNOM or FBT?
As of April 24, 2026, GNOM holds $51.60 M in assets under management (AUM), while FBT manages $2.31 B.
What sectors do the GNOM and FBT ETFs invest in?
GNOM leans toward sectors like Health Care. Meanwhile, FBT focuses on Health Care.
What are the top holdings of the GNOM ETF and FBT ETF?
GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. FBT holds in its top three: MODERNA INC, ALKERMES and UTD THERAPEUT.
Which ETF is more diversified: GNOM or FBT?
GNOM holds 47 securities with 66.21% of its assets in the top 15. FBT has 30 securities and a top 15 weight of 56.66%.
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Latest news about GNOM & FBT
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