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GNOMvsCANCETF Comparison

ETF 1

GNOM

Global X Genomics & Biotechnology ETF - USD

This fund is part of

BioTech & Genomics

-0.67%

Full GNOM fund page

VS

ETF 2

CANC

Tema Oncology ETF

This fund is part of

Tomorrow's Treatments

-0.34%

Full CANC fund page

Global X Genomics & Biotechnology ETF - USD (GNOM) belongs to the BioTech & Genomics segment. Tema Oncology ETF (CANC) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.99% for CANC. GNOM is up 0.74% year-to-date (YTD) with -$602K in YTD flows. CANC performs better with 10.62% YTD performance, and +$50M in YTD flows. Run a side-by-side ETF comparison of GNOM and CANC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs CANC performance and flow charts

Performance

Cumulative Flows

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Data Services

Historic performance and flows

Data as of 04/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	GNOM CANC	+7.67%+10.08%	-7.03%+5.34%	+0.74%+10.62%	+41.51%+55.67%	-6.56%n/a	-50.60%n/a
Flows	GNOM CANC	-$829K+$5M	+$1M+$29M	-$602K+$50M	-$14M+$70M	-$120M-	+$1M-

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	GNOM CANC	+28.47%+23.62%	+27.16%+23.46%	+28.79%n/a	+33.22%n/a
Max drawdown	GNOM CANC	-16.08%-7.99%	-18.16%-10.53%	-46.50%n/a	-72.17%n/a
Max drawdown duration	GNOM CANC	88d43d	92d32d	1075dn/a	1758dn/a

Trading data

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	GNOM	CANC
Last sale 4/27/2026 at 1:30 PM	$45.55	$37.78
Previous close 04/24/2026	$45.97	$38.36
Consolidated volume 04/24/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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CANC

is actively managed and doesn’t replicate an index

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	GNOM	CANC
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/27/2026 at 1:30 PM

Live

Closed

	GNOM	CANC
Last price	$45.55	$37.78
1D performance	-0.92%	-1.52%
AuM	$51.60 M	$179.70 M
E/R	0.5%	0.99%

Characteristics

	GNOM	CANC
Management strategy	Passive	Active
Provider	Global X	Tema
Benchmark	Solactive Genomics Index	-
N° of holdings	45	44
Asset class	Equities	-
Trailing 12m distribution yield	Join	Join
Inception date	April 5, 2019	August 15, 2023
ESG	No	No

More GNOM data on Trackinsight

More CANC data on Trackinsight

Exposure

Countries

GNOM

USA

87.57%

Other

12.43%

CANC

USA

85.51%

Other

14.49%

Sectors

GNOM

Health Care

88.49%

Other

11.51%

CANC

Health Care

78.17%

Other

21.83%

Diversification

GNOM

Total weight of top 15 holdings out of 15

66.21%

CANC

Total weight of top 15 holdings out of 15

56.1%

Top 15 holdings

Data as of March 31, 2026

GNOM

MODERNA INC

8.48%

ARROWHEAD PHARMACEUTICALS INC

6.21%

US74006W2070

6.13%

ILLUMINA

5.52%

GUARDANT HEALTH INC

5.18%

VERTEX PHARMACEUTICALS

4.61%

BIOMARIN PHARMACEUTICAL

4.59%

NATERA

4.21%

BIO-TECHNE CORP

3.64%

BIONTECH SE ADR

3.58%

CRISPR THERAPEUTICS

3.08%

BRISTOL-MYERS SQUIBB

3.05%

ALNYLAM PHARMACEUTICALS

2.85%

TWIST BIOSCIENCE CORP

2.54%

ASTRAZENECA

2.53%

CANC

REVOLUTION MEDICINES INC

4.95%

ASTRAZENECA

4.60%

NOVARTIS

4.45%

US7711951043

4.26%

LILLY

4.20%

BRIDGEBIO PHARMA

3.94%

COGENT BIOSCIENCES

3.88%

BRISTOL-MYERS SQUIBB

3.74%

MERCK & CO INC

3.62%

IMMUNOME

3.30%

JOHNSON&JOHNSON

3.23%

NUVALENT

3.20%

CELCUITY INC

3.07%

US3723032062

2.95%

ABBVIE

2.71%

Frequently asked questions about GNOM and CANC

How have the GNOM and CANC ETFs performed in 2026?

As of April 24, 2026, GNOM is up 0.74% year-to-date (YTD), while CANC has returned 10.62%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or CANC?

Year-to-date, the GNOM ETF saw -$602K in flows, compared to +$50M for CANC.

Which ETF is more volatile: GNOM or CANC?

Over the past year, GNOM had a volatility of 27.16%, while CANC experienced 23.46%.

Which ETF is bigger: GNOM or CANC?

As of April 24, 2026, GNOM holds $51.60 M in assets under management (AUM), while CANC manages $179.70 M.

What sectors do the GNOM and CANC ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, CANC focuses on Health Care.

What are the top holdings of the GNOM ETF and CANC ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. CANC holds in its top three: REVOLUTION MEDICINES INC, ASTRAZENECA and NOVARTIS.

GNOMvsCANCETF Comparison

Global X Genomics & Biotechnology ETF - USD

Tema Oncology ETF

GNOM vs CANC performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the GNOM and CANC ETFs performed in 2026?

As of April 24, 2026, GNOM is up 0.74% year-to-date (YTD), while CANC has returned 10.62%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or CANC?

Year-to-date, the GNOM ETF saw -$602K in flows, compared to +$50M for CANC.

Which ETF is more volatile: GNOM or CANC?

Over the past year, GNOM had a volatility of 27.16%, while CANC experienced 23.46%.

Which ETF is bigger: GNOM or CANC?

As of April 24, 2026, GNOM holds $51.60 M in assets under management (AUM), while CANC manages $179.70 M.

What sectors do the GNOM and CANC ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, CANC focuses on Health Care.

What are the top holdings of the GNOM ETF and CANC ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. CANC holds in its top three: REVOLUTION MEDICINES INC, ASTRAZENECA and NOVARTIS.

Which ETF is more diversified: GNOM or CANC?

GNOM holds 47 securities with 66.21% of its assets in the top 15. CANC has 54 securities and a top 15 weight of 56.1%.

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