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GNOMvsCANCETF Comparison

ETF 1
GNOM

Global X Genomics & Biotechnology ETF

This fund is part of
BioTech & Genomics
+3.75%
VS
ETF 2
CANC

Tema Oncology ETF

This fund is part of
Tomorrow's Treatments
+0.74%

Global X Genomics & Biotechnology ETF (GNOM) belongs to the BioTech & Genomics segment. Tema Oncology ETF (CANC) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.99% for CANC. GNOM is up 10.2% year-to-date (YTD) with +$4M in YTD flows. CANC performs worse with 8.24% YTD performance, and +$55M in YTD flows. Run a side-by-side ETF comparison of GNOM and CANC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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GNOM vs CANC performance and flow charts

Performance

0510%May 15May 22Jun 1Jun 8Jun 15

Cumulative Flows

0 M2 M4 M6 M8 MMay 15May 22Jun 1Jun 8Jun 15

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Historic performance and flows
Data as of 06/15/2026
1M3MYTD1Y3Y5Y
Perf.
GNOM
CANC
+13.00%+1.19%
+14.76%+2.71%
+10.20%+8.24%
+54.07%+48.63%
-1.12%n/a
-44.29%n/a
Flows
GNOM
CANC
+$4M+$7M
+$6M+$12M
+$4M+$55M
-$4M+$72M
-$104M-
+$5M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
GNOM
CANC
+31.68%+24.29%
+26.60%+22.60%
+28.96%n/a
+33.27%n/a
Max drawdown
GNOM
CANC
-7.88%-9.20%
-18.16%-9.20%
-45.66%n/a
-72.17%n/a
Max drawdown duration
GNOM
CANC
36d57d
144d57d
1096dn/a
1810dn/a
Trading data

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GNOM
CANC
Last sale
6/16/2026 at 2:04 PM
$50.22
$37.53
Previous close
06/15/2026
$50.10
$37.48
Consolidated volume
06/15/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of May 29, 2026
1-year trailing difference

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CANC
is actively managed and doesn’t replicate an index

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GNOM
CANC
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 6/16/2026 at 2:04 PM
Live
Closed
GNOM
CANC
Last price
$50.22
$37.53
1D performance
+0.24%
+0.13%
AuM$60.96 M$181.09 M
E/R0.5%0.99%
Characteristics
GNOM
CANC
Management strategyPassiveActive
ProviderGlobal XTema
BenchmarkSolactive Genomics Index-
N° of holdings4542
Asset classEquities-
Trailing 12m distribution yield
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Inception dateApril 5, 2019August 15, 2023
ESGNoNo
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Exposure

Countries

GNOM
USA
88%
Other
12%
CANC
USA
87.11%
Other
12.89%

Sectors

GNOM
Health Care
88.52%
Other
11.48%
CANC
Health Care
76.64%
Other
23.36%
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Diversification

GNOM

Total weight of top 15 holdings out of 15

66.44%
CANC

Total weight of top 15 holdings out of 15

54.47%

Top 15 holdings

Data as of April 30, 2026
GNOM
MODERNA INC
7.59%
ARROWHEAD PHARMACEUTICALS INC
7.18%
US74006W2070
6.77%
ILLUMINA
5.19%
GUARDANT HEALTH INC
4.73%
BIOMARIN PHARMACEUTICAL
4.29%
VERTEX PHARMACEUTICALS
4.16%
NATERA
4.14%
BIONTECH SE ADR
4.03%
BIO-TECHNE CORP
3.44%
CRISPR THERAPEUTICS
3.32%
TWIST BIOSCIENCE CORP
3.14%
LEGEND BIOTECH
2.91%
NL0015002SN0
2.77%
BRISTOL-MYERS SQUIBB
2.77%
CANC
REVOLUTION MEDICINES INC
6.51%
IMMUNOME
4.24%
US7711951043
4.15%
COGENT BIOSCIENCES
4.07%
NOVARTIS
4.00%
LILLY
3.81%
ASTRAZENECA
3.62%
BRISTOL-MYERS SQUIBB
3.36%
MERCK & CO INC
3.34%
CELCUITY INC
3.31%
NUVALENT
3.20%
BRIDGEBIO PHARMA
2.84%
US3723032062
2.82%
LEGEND BIOTECH
2.63%
US98887Q1040
2.57%
Frequently asked questions about GNOM and CANC

How have the GNOM and CANC ETFs performed in 2026?

As of June 15, 2026, GNOM is up 10.2% year-to-date (YTD), while CANC has returned 8.24%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: GNOM or CANC?

Year-to-date, the GNOM ETF saw +$4M in flows, compared to +$55M for CANC.

Which ETF is more volatile: GNOM or CANC?

Over the past year, GNOM had a volatility of 26.6%, while CANC experienced 22.6%.

Which ETF is bigger: GNOM or CANC?

As of June 15, 2026, GNOM holds $60.96 M in assets under management (AUM), while CANC manages $181.09 M.

What sectors do the GNOM and CANC ETFs invest in?

GNOM leans toward sectors like Health Care. Meanwhile, CANC focuses on Health Care.

What are the top holdings of the GNOM ETF and CANC ETF?

GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. CANC holds in its top three: REVOLUTION MEDICINES INC, IMMUNOME and US7711951043.

Which ETF is more diversified: GNOM or CANC?

GNOM holds 49 securities with 66.44% of its assets in the top 15. CANC has 53 securities and a top 15 weight of 54.47%.

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