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First Trust Health Care AlphaDEX Fund ETF (FXH) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. FXH is more expensive with a Total Expense Ratio (TER) of 0.61%, versus 0.58% for PBE. FXH is down -4.88% year-to-date (YTD) with -$40M in YTD flows. PBE performs worse with -7.11% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of FXH and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FXH PBE | -4.48%-5.55% | -5.96%-4.87% | -4.88%-7.11% | +5.66%+17.56% | +6.29%+26.51% | +2.41%+3.80% |
| Flows | FXH PBE | -$17M-$3M | -$40M+$969K | -$40M+$135K | -$160M-$32M | -$708M-$56M | -$511M-$39M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FXH PBE | +13.98%+19.01% | +18.35%+22.33% | +15.06%+20.20% | +16.53%+22.79% |
| Max drawdown | FXH PBE | -9.26%-11.05% | -11.60%-16.18% | -18.79%-22.21% | -29.40%-34.74% |
| Max drawdown duration | FXH PBE | 64d64d | 143d107d | 490d324d | 1648d1540d |
FXH | PBE | |
Last sale 3/13/2026 at 1:30 PM | $107.94 | $76.18 |
| Previous close 03/12/2026 | $108.23 | $76.18 |
| Consolidated volume 03/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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FXH | PBE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
FXH | PBE | |
|---|---|---|
| Last price | $107.94 | $76.18 |
| 1D performance | -0.27% | +0.00% |
| AuM | $854.71 M | $240.98 M |
| E/R | 0.61% | 0.58% |
FXH | PBE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | Invesco |
| Benchmark | StrataQuant Health Care Index | Dynamic Biotech & Genome Intellidex Index |
| N° of holdings | 71 | 30 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 8, 2007 | June 23, 2005 |
| ESG | No | No |
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
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