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FXHvsPBEETF Comparison

ETF 1
FXH

First Trust Health Care AlphaDEX Fund ETF

This fund is part of
US Health Care
-2%
Full FXH fund page
VS
ETF 2
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
-0.87%
Full PBE fund page

First Trust Health Care AlphaDEX Fund ETF (FXH) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. FXH is more expensive with a Total Expense Ratio (TER) of 0.61%, versus 0.58% for PBE. FXH is down -4.88% year-to-date (YTD) with -$40M in YTD flows. PBE performs worse with -7.11% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of FXH and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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FXH vs PBE performance and flow charts

Performance

-6.0-4.0-2.00.02.0%Feb 12Feb 20Feb 27Mar 6

Cumulative Flows

-15 M-10 M-5 M0 MFeb 12Feb 20Feb 27Mar 6

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Historic performance and flows
Data as of 03/12/2026
1M3MYTD1Y3Y5Y
Perf.
FXH
PBE
-4.48%-5.55%
-5.96%-4.87%
-4.88%-7.11%
+5.66%+17.56%
+6.29%+26.51%
+2.41%+3.80%
Flows
FXH
PBE
-$17M-$3M
-$40M+$969K
-$40M+$135K
-$160M-$32M
-$708M-$56M
-$511M-$39M
Volatility and drawdown
3M1Y3Y5Y
Volatility
FXH
PBE
+13.98%+19.01%
+18.35%+22.33%
+15.06%+20.20%
+16.53%+22.79%
Max drawdown
FXH
PBE
-9.26%-11.05%
-11.60%-16.18%
-18.79%-22.21%
-29.40%-34.74%
Max drawdown duration
FXH
PBE
64d64d
143d107d
490d324d
1648d1540d
Trading data

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FXH
PBE
Last sale
3/13/2026 at 1:30 PM
$107.94
$76.18
Previous close
03/12/2026
$108.23
$76.18
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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FXH
PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
FXH
PBE
Last price
$107.94
$76.18
1D performance
-0.27%
+0.00%
AuM$854.71 M$240.98 M
E/R0.61%0.58%
Characteristics
FXH
PBE
Management strategyPassivePassive
ProviderFirst TrustInvesco
BenchmarkStrataQuant Health Care IndexDynamic Biotech & Genome Intellidex Index
N° of holdings7130
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateMay 8, 2007June 23, 2005
ESGNoNo
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Exposure

Countries

FXH
USA
94.66%
Other
5.34%
PBE
USA
94.25%
Other
5.75%

Sectors

FXH
Health Care
93.03%
Other
6.97%
PBE
Health Care
96.95%
Other
3.05%
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Diversification

FXH

Total weight of top 15 holdings out of 15

33.8%
PBE

Total weight of top 15 holdings out of 15

61.48%

Top 15 holdings

Data as of January 31, 2026
FXH
ORGANON & CO
2.64%
PFIZER
2.36%
CARDINAL HEALTH
2.32%
IONIS PHARMACEUTICALS INC
2.32%
HCA HEALTHCARE
2.32%
MOLINA HLTHCRE
2.30%
MEDPACE HOLDINGS INC
2.30%
BIOGEN INC
2.27%
INCYTE
2.25%
NATERA
2.24%
US83444M1018
2.15%
LILLY
2.14%
ACADIA HEALTHCARE COMPANY
2.10%
UNIVERSAL HEALTH SERVICES
2.05%
PENUMBRA
2.04%
PBE
ILLUMINA
5.91%
GILEAD SCIENCES
5.35%
AMGEN-T
5.09%
REGENERON PHARMACEUTICALS
4.87%
UTD THERAPEUT
4.83%
BIOGEN INC
4.76%
INCYTE
4.70%
ALNYLAM PHARMACEUTICALS
4.05%
AMICUS THERAPEUTICS
3.83%
DYNAVAX TECHNOLOGIES
3.60%
NL0015002SN0
3.05%
ACADIA PHARMACEUTICALS
2.98%
MANNKIND
2.89%
BIO-TECHNE CORP
2.83%
EXELIXIS
2.74%
Frequently asked questions about FXH and PBE

How have the FXH and PBE ETFs performed in 2026?

As of March 12, 2026, FXH is down -4.88% year-to-date (YTD), while PBE has lost -7.11%. That puts FXH better performer ahead so far this year.

Which ETF is attracting more investor money: FXH or PBE?

Year-to-date, the FXH ETF saw -$40M in flows, compared to +$135K for PBE.

Which ETF is more volatile: FXH or PBE?

Over the past year, FXH had a volatility of 18.35%, while PBE experienced 22.33%.

Which ETF is bigger: FXH or PBE?

As of March 12, 2026, FXH holds $854.71 M in assets under management (AUM), while PBE manages $240.98 M.

What sectors do the FXH and PBE ETFs invest in?

FXH leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the FXH ETF and PBE ETF?

FXH top holdings include ORGANON & CO, PFIZER and CARDINAL HEALTH. PBE holds in its top three: ILLUMINA, GILEAD SCIENCES and AMGEN-T.

Which ETF is more diversified: FXH or PBE?

FXH holds 75 securities with 33.8% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 61.48%.

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