FXHvsFTXHETF Comparison
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First Trust Health Care AlphaDEX Fund ETF (FXH) and First Trust Nasdaq Pharmaceuticals ETF (FTXH) belong to the same industry segment: US Health Care. Both ETFs have the same top 1 sector exposures: Healthcare. FXH is more expensive with a Total Expense Ratio (TER) of 0.61%, versus 0.6% for FTXH. FXH is up 16.21% year-to-date (YTD) with +$65M in YTD flows. FTXH performs better with 26.05% YTD performance, and +$1.11B in YTD flows. Run a side-by-side ETF comparison of FXH and FTXH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FXH vs FTXH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/17/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FXH FTXH | +0.53%+2.91% | +13.98%+16.24% | +16.21%+26.05% | +22.70%+49.52% | +33.57%+63.96% | +7.15%+72.99% |
| Flows | FXH FTXH | +$20M+$161M | +$120M+$1.10B | +$65M+$1.11B | +$44M+$1.11B | -$498M+$1.10B | -$437M+$1.10B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FXH FTXH | +15.66%+19.83% | +15.54%+17.58% | +15.63%+17.00% | +16.94%+16.35% |
| Max drawdown | FXH FTXH | -4.40%-5.41% | -12.07%-7.50% | -17.66%-19.32% | -28.28%-19.32% |
| Max drawdown duration | FXH FTXH | 23d23d | 168d99d | 395d393d | 1742d393d |
Trading data
FXH | FTXH | |
Last sale 9/21/2026 at 1:30 PM | $130.87 | $41.33 |
| Previous close 09/18/2026 | $130.77 | $41.09 |
| Consolidated volume 09/18/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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FXH | FTXH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/21/2026 at 1:30 PM
Live
Closed
FXH | FTXH | |
|---|---|---|
| Last price | $130.87 | $41.33 |
| 1D performance | +0.08% | +0.59% |
| AuM | $1.15 B | $1.19 B |
| E/R | 0.61% | 0.6% |
Characteristics
FXH | FTXH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | First Trust |
| Benchmark | StrataQuant Health Care Index | NASDAQ US Smart Pharmaceuticals Index |
| N° of holdings | 72 | 49 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 8, 2007 | September 20, 2016 |
| ESG | No | No |
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Exposure
Countries
FXH
USA
93.07%
Other
6.93%
FTXH
USA
95.79%
Other
4.21%
Sectors
FXH
Healthcare
98.24%
Other
1.76%
FTXH
Healthcare
99.86%
Other
0.14%
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Diversification
FXH
Total weight of top 15 holdings out of 15
35.54%
FTXH
Total weight of top 15 holdings out of 15
66.98%
Top 15 holdings
Data as of July 31, 2026
FXH
Regeneron Pharmaceuticals, Inc.
2.85%
Natera, Inc.
2.57%
Universal Health Services, Inc.
2.50%
Boston Scientific Corp.
2.49%
Pfizer Inc.
2.48%
Solventum Corp.
2.47%
Zimmer Biomet Holdings, Inc.
2.47%
Guardant Health, Inc.
2.41%
Tenet Healthcare Corp.
2.34%
Globus Medical, Inc.
2.33%
Corcept Therapeutics, Inc.
2.24%
Halozyme Therapeutics, Inc.
2.18%
Centene Corp.
2.15%
The Cigna Group
2.14%
Encompass Health Corp.
1.92%
FTXH
Merck & Co., Inc.
7.58%
Eli Lilly & Co.
7.43%
AbbVie, Inc.
7.11%
Johnson & Johnson
6.78%
Bristol Myers Squibb Co.
6.61%
Amgen, Inc.
3.53%
Biogen, Inc.
3.52%
Vertex Pharmaceuticals, Inc.
3.43%
Viatris, Inc.
3.40%
Regeneron Pharmaceuticals, Inc.
3.34%
Pfizer Inc.
3.17%
Cardinal Health, Inc.
3.14%
Gilead Sciences, Inc.
3.03%
Incyte Corp.
2.48%
United Therapeutics Corp.
2.43%
Frequently asked questions about FXH and FTXH
How have the FXH and FTXH ETFs performed in 2026?
As of September 17, 2026, FXH is up 16.21% year-to-date (YTD), while FTXH has returned 26.05%. That puts FTXH better performer ahead so far this year.
Which ETF is attracting more investor money: FXH or FTXH?
Year-to-date, the FXH ETF saw +$65M in flows, compared to +$1.11B for FTXH.
Which ETF is more volatile: FXH or FTXH?
Over the past year, FXH had a volatility of 15.54%, while FTXH experienced 17.58%.
Which ETF is bigger: FXH or FTXH?
As of September 17, 2026, FXH holds $1.15 B in assets under management (AUM), while FTXH manages $1.19 B.
What sectors do the FXH and FTXH ETFs invest in?
FXH leans toward sectors like Healthcare. Meanwhile, FTXH focuses on Healthcare.
What are the top holdings of the FXH ETF and FTXH ETF?
FXH top holdings include Regeneron Pharmaceuticals, Inc., Natera, Inc. and Universal Health Services, Inc.. FTXH holds in its top three: Merck & Co., Inc., Eli Lilly & Co. and AbbVie, Inc..
Which ETF is more diversified: FXH or FTXH?
FXH holds 72 securities with 35.54% of its assets in the top 15. FTXH has 49 securities and a top 15 weight of 66.98%.
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