FXHvsFTXHETF Comparison
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First Trust Health Care AlphaDEX Fund ETF (FXH) and First Trust Nasdaq Pharmaceuticals ETF (FTXH) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. FXH is more expensive with a Total Expense Ratio (TER) of 0.61%, versus 0.6% for FTXH. FXH is down -0.82% year-to-date (YTD) with -$61M in YTD flows. FTXH performs better with 2.18% YTD performance, and +$9M in YTD flows. Run a side-by-side ETF comparison of FXH and FTXH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FXH vs FTXH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FXH FTXH | +6.43%+1.62% | -4.04%-0.72% | -0.82%+2.18% | +14.86%+36.03% | +3.56%+30.54% | -1.76%+36.84% |
| Flows | FXH FTXH | -$11M+$2M | -$67M+$7M | -$61M+$9M | -$123M+$11M | -$719M-$7M | -$505M+$3M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FXH FTXH | +17.11%+17.61% | +16.17%+18.13% | +15.26%+16.09% | +16.67%+15.80% |
| Max drawdown | FXH FTXH | -10.81%-7.50% | -12.07%-7.50% | -18.39%-19.32% | -29.40%-19.32% |
| Max drawdown duration | FXH FTXH | 88d54d | 107d54d | 464d393d | 1691d393d |
Trading data
FXH | FTXH | |
Last sale 4/27/2026 at 1:30 PM | $113.62 | $33.49 |
| Previous close 04/27/2026 | $112.52 | $33.64 |
| Consolidated volume 04/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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FXH | FTXH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
FXH | FTXH | |
|---|---|---|
| Last price | $113.62 | $33.49 |
| 1D performance | +0.97% | -0.44% |
| AuM | $867.08 M | $30.23 M |
| E/R | 0.61% | 0.6% |
Characteristics
FXH | FTXH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | First Trust |
| Benchmark | StrataQuant Health Care Index | NASDAQ US Smart Pharmaceuticals Index |
| N° of holdings | 71 | 50 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 8, 2007 | September 20, 2016 |
| ESG | No | No |
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Exposure
Countries
FXH
USA
95.47%
Other
4.53%
FTXH
USA
96.17%
Other
3.83%
Sectors
FXH
Health Care
93.76%
Other
6.24%
FTXH
Health Care
99.23%
Other
0.77%
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Diversification
FXH
Total weight of top 15 holdings out of 15
35.37%
FTXH
Total weight of top 15 holdings out of 15
71%
Top 15 holdings
Data as of March 31, 2026
FXH
ACADIA HEALTHCARE COMPANY
3.83%
APELLIS PHARMACEUTICALS
2.95%
PFIZER
2.63%
BIOGEN INC
2.40%
CARDINAL HEALTH
2.37%
HCA HEALTHCARE
2.33%
INCYTE
2.19%
IONIS PHARMACEUTICALS INC
2.18%
INSMED
2.17%
UTD THERAPEUT
2.15%
MERCK & CO INC
2.11%
LILLY
2.04%
NATERA
2.04%
MEDPACE HOLDINGS INC
2.00%
AMGEN-T
1.98%
FTXH
BRISTOL-MYERS SQUIBB
7.45%
JOHNSON&JOHNSON
7.39%
MERCK & CO INC
7.34%
ABBVIE
6.97%
LILLY
6.83%
PFIZER
3.88%
REGENERON PHARMACEUTICALS
3.74%
BIOGEN INC
3.60%
GILEAD SCIENCES
3.54%
CARDINAL HEALTH
3.48%
VIATRIS INC
3.43%
AMGEN-T
3.42%
VERTEX PHARMACEUTICALS
3.39%
ZOETIS INC
3.37%
UTD THERAPEUT
3.17%
Frequently asked questions about FXH and FTXH
How have the FXH and FTXH ETFs performed in 2026?
As of April 24, 2026, FXH is down -0.82% year-to-date (YTD), while FTXH has returned 2.18%. That puts FTXH better performer ahead so far this year.
Which ETF is attracting more investor money: FXH or FTXH?
Year-to-date, the FXH ETF saw -$61M in flows, compared to +$9M for FTXH.
Which ETF is more volatile: FXH or FTXH?
Over the past year, FXH had a volatility of 16.17%, while FTXH experienced 18.13%.
Which ETF is bigger: FXH or FTXH?
As of April 24, 2026, FXH holds $867.08 M in assets under management (AUM), while FTXH manages $30.23 M.
What sectors do the FXH and FTXH ETFs invest in?
FXH leans toward sectors like Health Care. Meanwhile, FTXH focuses on Health Care.
What are the top holdings of the FXH ETF and FTXH ETF?
FXH top holdings include ACADIA HEALTHCARE COMPANY, APELLIS PHARMACEUTICALS and PFIZER. FTXH holds in its top three: BRISTOL-MYERS SQUIBB, JOHNSON&JOHNSON and MERCK & CO INC.
Which ETF is more diversified: FXH or FTXH?
FXH holds 75 securities with 35.37% of its assets in the top 15. FTXH has 50 securities and a top 15 weight of 71%.
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