FTXHvsIYHETF Comparison
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First Trust Nasdaq Pharmaceuticals ETF (FTXH) and iShares U.S. Healthcare ETF (IYH) belong to the same industry segment: US Health Care. FTXH's top 1 sector exposures are Healthcare. In contrast, IYH's top sector exposures are Healthcare, Non-Corporate and Finance. FTXH is more expensive with a Total Expense Ratio (TER) of 0.6%, versus 0.37% for IYH. FTXH is up 31.84% year-to-date (YTD) with +$1.02B in YTD flows. IYH performs worse with 17.4% YTD performance, and +$375M in YTD flows. Run a side-by-side ETF comparison of FTXH and IYH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FTXH vs IYH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/28/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FTXH IYH | +3.28%+4.28% | +9.09%+8.17% | +31.84%+17.40% | +47.80%+25.24% | +87.39%+51.94% | +77.36%+40.29% |
| Flows | FTXH IYH | +$41M+$340M | +$176M+$693M | +$1.02B+$375M | +$1.02B+$737M | +$1.02B+$416M | +$1.02B+$577M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FTXH IYH | +18.78%+17.15% | +17.62%+16.45% | +17.11%+15.15% | +16.43%+15.50% |
| Max drawdown | FTXH IYH | -5.45%-5.88% | -7.50%-10.72% | -19.32%-17.89% | -19.32%-17.89% |
| Max drawdown duration | FTXH IYH | 57d56d | 99d169d | 393d445d | 393d445d |
Trading data
FTXH | IYH | |
Last sale 10/29/2026 at 1:30 PM | $43.77 | $77.55 |
| Previous close 10/28/2026 | $43.25 | $75.84 |
| Consolidated volume 10/28/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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FTXH | IYH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Main metrics
Last update 10/29/2026 at 1:30 PM
Live
Closed
FTXH | IYH | |
|---|---|---|
| Last price | $43.77 | $77.55 |
| 1D performance | +1.22% | +2.25% |
| AuM | $1.16 B | $4.52 B |
| E/R | 0.6% | 0.37% |
Characteristics
FTXH | IYH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | NASDAQ US Smart Pharmaceuticals Index | Russell 1000 Health Care RIC 22.5/45 Capped Gross Index |
| N° of holdings | 49 | 101 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 20, 2016 | June 12, 2000 |
| ESG | No | No |
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Exposure
Countries
FTXH
USA
95.82%
Other
4.18%
IYH
USA
96.86%
Other
3.14%
Sectors
FTXH
Healthcare
99.79%
Other
0.21%
IYH
Healthcare
99.79%
Other
0.21%
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Diversification
FTXH
Total weight of top 15 holdings out of 15
67.15%
IYH
Total weight of top 15 holdings out of 15
68.68%
Top 15 holdings
Data as of August 31, 2026
FTXH
Merck & Co., Inc.
7.62%
AbbVie, Inc.
7.05%
Eli Lilly & Co.
6.92%
Johnson & Johnson
6.87%
Bristol Myers Squibb Co.
6.75%
Amgen, Inc.
3.56%
Biogen, Inc.
3.54%
Viatris, Inc.
3.51%
Vertex Pharmaceuticals, Inc.
3.48%
Regeneron Pharmaceuticals, Inc.
3.33%
Cardinal Health, Inc.
3.29%
Pfizer Inc.
3.25%
Gilead Sciences, Inc.
3.16%
Incyte Corp.
2.43%
United Therapeutics Corp.
2.39%
IYH
Eli Lilly & Co.
14.45%
Johnson & Johnson
10.02%
AbbVie, Inc.
7.10%
Merck & Co., Inc.
5.72%
UnitedHealth Group, Inc.
5.50%
Amgen, Inc.
3.63%
Thermo Fisher Scientific, Inc.
3.59%
Abbott Laboratories
2.99%
Gilead Sciences, Inc.
2.84%
Pfizer Inc.
2.53%
Vertex Pharmaceuticals, Inc.
2.17%
Bristol Myers Squibb Co.
2.13%
Danaher Corp.
2.11%
Intuitive Surgical, Inc.
2.08%
Medtronic Plc
1.82%
Frequently asked questions about FTXH and IYH
How have the FTXH and IYH ETFs performed in 2026?
As of October 28, 2026, FTXH is up 31.84% year-to-date (YTD), while IYH has returned 17.4%. That puts FTXH better performer ahead so far this year.
Which ETF is attracting more investor money: FTXH or IYH?
Year-to-date, the FTXH ETF saw +$1.02B in flows, compared to +$375M for IYH.
Which ETF is more volatile: FTXH or IYH?
Over the past year, FTXH had a volatility of 17.62%, while IYH experienced 16.45%.
Which ETF is bigger: FTXH or IYH?
As of October 28, 2026, FTXH holds $1.16 B in assets under management (AUM), while IYH manages $4.52 B.
What sectors do the FTXH and IYH ETFs invest in?
FTXH leans toward sectors like Healthcare. Meanwhile, IYH focuses on Healthcare.
What are the top holdings of the FTXH ETF and IYH ETF?
FTXH top holdings include Merck & Co., Inc., AbbVie, Inc. and Eli Lilly & Co.. IYH holds in its top three: Eli Lilly & Co., Johnson & Johnson and AbbVie, Inc..
Which ETF is more diversified: FTXH or IYH?
FTXH holds 49 securities with 67.15% of its assets in the top 15. IYH has 101 securities and a top 15 weight of 68.68%.
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Latest news about FTXH & IYH
Health Care Sector Down After a Cyberattack on UnitedHealth
March 4, 2024
IYH
Healthcare Stocks Rebound
August 14, 2023
IYH
Continued tightening of the U.S. labor market
September 23, 2022
IYH
U.S. labor market facing tight conditions
July 5, 2022
IYH
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