FTXHvsFXHETF Comparison
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First Trust Nasdaq Pharmaceuticals ETF (FTXH) and First Trust Health Care AlphaDEX Fund ETF (FXH) belong to the same industry segment: US Health Care. Both ETFs have the same top 1 sector exposures: Healthcare. FTXH is less expensive with a Total Expense Ratio (TER) of 0.6%, versus 0.61% for FXH. FTXH is up 23.32% year-to-date (YTD) with +$978M in YTD flows. FXH performs worse with 14.02% YTD performance, and +$65M in YTD flows. Run a side-by-side ETF comparison of FTXH and FXH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FTXH vs FXH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/10/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FTXH FXH | +0.75%-2.16% | +14.81%+10.97% | +23.32%+14.02% | +46.70%+20.73% | +58.20%+28.88% | +66.91%+4.62% |
| Flows | FTXH FXH | +$41M+$33M | +$968M+$138M | +$978M+$65M | +$981M+$44M | +$973M-$498M | +$977M-$437M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FTXH FXH | +20.07%+15.75% | +17.74%+15.73% | +16.99%+15.61% | +16.34%+16.93% |
| Max drawdown | FTXH FXH | -5.34%-4.40% | -7.50%-12.07% | -19.32%-17.66% | -19.32%-28.29% |
| Max drawdown duration | FTXH FXH | 16d16d | 99d168d | 393d395d | 393d1753d |
Trading data
FTXH | FXH | |
Last sale 9/11/2026 at 1:30 PM | $40.47 | $129.66 |
| Previous close 09/10/2026 | $40.52 | $129.30 |
| Consolidated volume 09/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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FTXH | FXH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/11/2026 at 1:30 PM
Live
Closed
FTXH | FXH | |
|---|---|---|
| Last price | $40.47 | $129.66 |
| 1D performance | -0.13% | +0.28% |
| AuM | $1.04 B | $1.13 B |
| E/R | 0.6% | 0.61% |
Characteristics
FTXH | FXH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | First Trust |
| Benchmark | NASDAQ US Smart Pharmaceuticals Index | StrataQuant Health Care Index |
| N° of holdings | 49 | 72 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 20, 2016 | May 8, 2007 |
| ESG | No | No |
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Exposure
Countries
FTXH
USA
95.79%
Other
4.21%
FXH
USA
93.07%
Other
6.93%
Sectors
FTXH
Healthcare
99.86%
Other
0.14%
FXH
Healthcare
98.24%
Other
1.76%
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Diversification
FTXH
Total weight of top 15 holdings out of 15
66.98%
FXH
Total weight of top 15 holdings out of 15
35.54%
Top 15 holdings
Data as of July 31, 2026
FTXH
Merck & Co., Inc.
7.58%
Eli Lilly & Co.
7.43%
AbbVie, Inc.
7.11%
Johnson & Johnson
6.78%
Bristol Myers Squibb Co.
6.61%
Amgen, Inc.
3.53%
Biogen, Inc.
3.52%
Vertex Pharmaceuticals, Inc.
3.43%
Viatris, Inc.
3.40%
Regeneron Pharmaceuticals, Inc.
3.34%
Pfizer Inc.
3.17%
Cardinal Health, Inc.
3.14%
Gilead Sciences, Inc.
3.03%
Incyte Corp.
2.48%
United Therapeutics Corp.
2.43%
FXH
Regeneron Pharmaceuticals, Inc.
2.85%
Natera, Inc.
2.57%
Universal Health Services, Inc.
2.50%
Boston Scientific Corp.
2.49%
Pfizer Inc.
2.48%
Zimmer Biomet Holdings, Inc.
2.47%
Solventum Corp.
2.47%
Guardant Health, Inc.
2.41%
Tenet Healthcare Corp.
2.34%
Globus Medical, Inc.
2.33%
Corcept Therapeutics, Inc.
2.24%
Halozyme Therapeutics, Inc.
2.18%
Centene Corp.
2.15%
The Cigna Group
2.14%
Encompass Health Corp.
1.92%
Frequently asked questions about FTXH and FXH
How have the FTXH and FXH ETFs performed in 2026?
As of September 10, 2026, FTXH is up 23.32% year-to-date (YTD), while FXH has returned 14.02%. That puts FTXH better performer ahead so far this year.
Which ETF is attracting more investor money: FTXH or FXH?
Year-to-date, the FTXH ETF saw +$978M in flows, compared to +$65M for FXH.
Which ETF is more volatile: FTXH or FXH?
Over the past year, FTXH had a volatility of 17.74%, while FXH experienced 15.73%.
Which ETF is bigger: FTXH or FXH?
As of September 10, 2026, FTXH holds $1.04 B in assets under management (AUM), while FXH manages $1.13 B.
What sectors do the FTXH and FXH ETFs invest in?
FTXH leans toward sectors like Healthcare. Meanwhile, FXH focuses on Healthcare.
What are the top holdings of the FTXH ETF and FXH ETF?
FTXH top holdings include Merck & Co., Inc., Eli Lilly & Co. and AbbVie, Inc.. FXH holds in its top three: Regeneron Pharmaceuticals, Inc., Natera, Inc. and Universal Health Services, Inc..
Which ETF is more diversified: FTXH or FXH?
FTXH holds 49 securities with 66.98% of its assets in the top 15. FXH has 72 securities and a top 15 weight of 35.54%.
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