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FMEDvsWDNAETF Comparison

ETF 1

FMED

Fidelity Disruptive Medicine ETF

This fund is part of

Multiple Trends

+2.93%

Full FMED fund page

VS

ETF 2

WDNA

WisdomTree BioRevolution Fund

This fund is part of

BioTech & Genomics

+0.66%

Full WDNA fund page

Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. WisdomTree BioRevolution Fund (WDNA) is part of the BioTech & Genomics segment. FMED's top 1 sector exposures are Healthcare. In contrast, WDNA's top sector exposures are Healthcare, Non-Energy Materials and Consumer Non-Cyclicals. FMED is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.45% for WDNA. FMED is up 17.43% year-to-date (YTD) with -$17M in YTD flows. WDNA performs better with 38.71% YTD performance, and +$1M in YTD flows. Run a side-by-side ETF comparison of FMED and WDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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FMED vs WDNA performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

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Historic performance and flows

Data as of 09/21/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	FMED WDNA	-2.40%-0.68%	+21.48%+23.59%	+17.43%+38.71%	+29.04%+61.24%	+43.82%+62.78%	n/a-6.36%
Flows	FMED WDNA	-+$2M	-+$2M	-$17M+$1M	-$14M+$1M	-$3M+$1M	-+$3M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	FMED WDNA	+24.66%+34.78%	+21.06%+27.97%	+19.25%+26.37%	n/a+25.78%
Max drawdown	FMED WDNA	-7.15%-9.35%	-17.78%-11.90%	-19.20%-36.45%	n/a-57.38%
Max drawdown duration	FMED WDNA	29d42d	212d147d	267d595d	n/a1824d

Trading data

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	FMED	WDNA
Last sale 9/22/2026 at 1:30 PM		$23.92
Previous close 09/21/2026		$23.43
Consolidated volume 09/21/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of September 22, 2026

1-year trailing difference

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FMED

is actively managed and doesn’t replicate an index

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	FMED	WDNA
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 9/22/2026 at 1:30 PM

Live

Closed

	FMED	WDNA
Last price	–	$23.92
1D performance	–	+2.08%
AuM	$51.66 M	$4.69 M
E/R	0.5%	0.45%

Characteristics

	FMED	WDNA
Management strategy	Active	Passive
Provider	Fidelity	WisdomTree
Benchmark	-	WisdomTree BioRevolution Index
N° of holdings	74	79
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 12, 2023	June 3, 2021
ESG	No	No

More FMED data on Trackinsight

More WDNA data on Trackinsight

Exposure

Countries

FMED

USA

83.4%

Other

16.6%

WDNA

USA

83.75%

Other

16.25%

Sectors

FMED

Healthcare

100%

Other

0%

WDNA

Healthcare

88.38%

Non-Energy Materi.

7.38%

Other

4.25%

Diversification

FMED

Total weight of top 15 holdings out of 15

43.09%

WDNA

Total weight of top 15 holdings out of 15

40.46%

Top 15 holdings

Data as of July 31, 2026

FMED

10X Genomics, Inc.

4.48%

Thermo Fisher Scientific, Inc.

3.98%

Danaher Corp.

3.86%

Lifestance Health Group, Inc.

3.15%

Alnylam Pharmaceuticals, Inc.

3.10%

argenx SE

2.99%

Cogent Biosciences, Inc.

2.98%

Revolution Medicines, Inc.

2.85%

Illumina, Inc.

2.62%

Intuitive Surgical, Inc.

2.34%

Kymera Therapeutics, Inc.

2.29%

UnitedHealth Group, Inc.

2.24%

Ascendis Pharma A/S

2.12%

Kiniksa Pharmaceuticals International Plc

2.06%

UCB SA

2.03%

WDNA

Twist Bioscience Corp.

5.53%

Eli Lilly & Co.

4.11%

Moderna, Inc.

3.59%

Johnson & Johnson

3.13%

Immunome, Inc.

2.57%

United Therapeutics Corp.

2.50%

10X Genomics, Inc.

2.44%

Natera, Inc.

2.42%

Darling Ingredients, Inc.

2.26%

Corteva, Inc.

2.19%

Structure Therapeutics, Inc.

2.04%

Stoke Therapeutics, Inc.

2.02%

Krystal Biotech, Inc.

2.01%

Thermo Fisher Scientific, Inc.

1.83%

Tempus AI, Inc.

1.82%

Frequently asked questions about FMED and WDNA

How have the FMED and WDNA ETFs performed in 2026?

As of September 21, 2026, FMED is up 17.43% year-to-date (YTD), while WDNA has returned 38.71%. That puts WDNA better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or WDNA?

Year-to-date, the FMED ETF saw -$17M in flows, compared to +$1M for WDNA.

Which ETF is more volatile: FMED or WDNA?

Over the past year, FMED had a volatility of 21.06%, while WDNA experienced 27.97%.

Which ETF is bigger: FMED or WDNA?

As of September 21, 2026, FMED holds $51.66 M in assets under management (AUM), while WDNA manages $4.69 M.

What sectors do the FMED and WDNA ETFs invest in?

FMED leans toward sectors like Healthcare. Meanwhile, WDNA focuses on Healthcare and Non-Energy Materials.

What are the top holdings of the FMED ETF and WDNA ETF?

FMED top holdings include 10X Genomics, Inc., Thermo Fisher Scientific, Inc. and Danaher Corp.. WDNA holds in its top three: Twist Bioscience Corp., Eli Lilly & Co. and Moderna, Inc..

FMEDvsWDNAETF Comparison

Fidelity Disruptive Medicine ETF

WisdomTree BioRevolution Fund

FMED vs WDNA performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the FMED and WDNA ETFs performed in 2026?

As of September 21, 2026, FMED is up 17.43% year-to-date (YTD), while WDNA has returned 38.71%. That puts WDNA better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or WDNA?

Year-to-date, the FMED ETF saw -$17M in flows, compared to +$1M for WDNA.

Which ETF is more volatile: FMED or WDNA?

Over the past year, FMED had a volatility of 21.06%, while WDNA experienced 27.97%.

Which ETF is bigger: FMED or WDNA?

As of September 21, 2026, FMED holds $51.66 M in assets under management (AUM), while WDNA manages $4.69 M.

What sectors do the FMED and WDNA ETFs invest in?

FMED leans toward sectors like Healthcare. Meanwhile, WDNA focuses on Healthcare and Non-Energy Materials.

What are the top holdings of the FMED ETF and WDNA ETF?

FMED top holdings include 10X Genomics, Inc., Thermo Fisher Scientific, Inc. and Danaher Corp.. WDNA holds in its top three: Twist Bioscience Corp., Eli Lilly & Co. and Moderna, Inc..

Which ETF is more diversified: FMED or WDNA?

FMED holds 74 securities with 43.09% of its assets in the top 15. WDNA has 79 securities and a top 15 weight of 40.46%.

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