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FMEDvsWDNAETF Comparison

ETF 1

FMED

Fidelity Disruptive Medicine ETF

This fund is part of

Multiple Trends

-6.5%

Full FMED fund page

VS

ETF 2

WDNA

WisdomTree BioRevolution Fund

This fund is part of

BioTech & Genomics

-1.76%

Full WDNA fund page

Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. WisdomTree BioRevolution Fund (WDNA) is part of the BioTech & Genomics segment. FMED's top 1 sector exposures are Healthcare. In contrast, WDNA's top sector exposures are Healthcare, Non-Energy Materials and Consumer Non-Cyclicals. FMED is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.45% for WDNA. FMED is up 14.76% year-to-date (YTD) with -$20M in YTD flows. WDNA performs better with 33.87% YTD performance, and +$1M in YTD flows. Run a side-by-side ETF comparison of FMED and WDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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FMED vs WDNA performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

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Historic performance and flows

Data as of 11/05/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	FMED WDNA	-4.35%-6.50%	+7.81%+12.01%	+14.76%+33.87%	+19.85%+45.21%	+48.91%+65.56%	n/a-7.11%
Flows	FMED WDNA	-$3M+$239K	-$3M+$2M	-$20M+$1M	-$18M+$1M	-$15M+$1M	-+$3M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	FMED WDNA	+31.58%+40.83%	+24.11%+28.98%	+20.23%+26.99%	n/a+26.31%
Max drawdown	FMED WDNA	-7.63%-8.16%	-17.78%-11.90%	-19.20%-36.45%	n/a-55.67%
Max drawdown duration	FMED WDNA	69d7d	212d147d	267d595d	n/a1814d

Trading data

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	FMED	WDNA
Last sale 11/6/2026 at 2:30 PM		$23.09
Previous close 11/04/2026		$22.77
Consolidated volume 11/04/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of November 7, 2026

1-year trailing difference

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FMED

is actively managed and doesn’t replicate an index

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	FMED	WDNA
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 11/6/2026 at 2:30 PM

Live

Closed

	FMED	WDNA
Last price	–	$23.09
1D performance	–	+1.41%
AuM	$47.38 M	$4.75 M
E/R	0.5%	0.45%

Characteristics

	FMED	WDNA
Management strategy	Active	Passive
Provider	Fidelity	WisdomTree
Benchmark	-	WisdomTree BioRevolution ESG Screened Index
N° of holdings	71	79
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 12, 2023	June 3, 2021
ESG	No	Yes

More FMED data on Trackinsight

More WDNA data on Trackinsight

Exposure

Countries

FMED

USA

84.97%

Other

15.03%

WDNA

USA

86.29%

Other

13.71%

Sectors

FMED

Healthcare

99.49%

Other

0.51%

WDNA

Healthcare

90.77%

Other

9.23%

Diversification

FMED

Total weight of top 15 holdings out of 15

47.18%

WDNA

Total weight of top 15 holdings out of 15

50.08%

Top 15 holdings

Data as of September 30, 2026

FMED

10X Genomics, Inc.

5.82%

Natera, Inc.

4.47%

Thermo Fisher Scientific, Inc.

4.19%

Danaher Corp.

3.92%

Illumina, Inc.

3.56%

argenx SE

2.96%

Lifestance Health Group, Inc.

2.87%

Revolution Medicines, Inc.

2.86%

Sartorius Stedim Biotech SA

2.72%

Moderna, Inc.

2.62%

Alnylam Pharmaceuticals, Inc.

2.48%

HeartFlow, Inc.

2.39%

Intuitive Surgical, Inc.

2.20%

Cogent Biosciences, Inc.

2.13%

Caris Life Sciences, Inc.

1.99%

WDNA

Moderna, Inc.

10.44%

Twist Bioscience Corp.

9.31%

10X Genomics, Inc.

3.68%

Eli Lilly & Co.

3.47%

Natera, Inc.

3.09%

Tempus AI, Inc.

2.82%

Johnson & Johnson

2.69%

Iovance Biotherapeutics, Inc.

2.32%

Immunome, Inc.

2.02%

United Therapeutics Corp.

1.86%

Darling Ingredients, Inc.

1.85%

Thermo Fisher Scientific, Inc.

1.75%

Revolution Medicines, Inc.

1.60%

Corteva, Inc.

1.58%

CRISPR Therapeutics AG

1.58%

Frequently asked questions about FMED and WDNA

How have the FMED and WDNA ETFs performed in 2026?

As of November 5, 2026, FMED is up 14.76% year-to-date (YTD), while WDNA has returned 33.87%. That puts WDNA better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or WDNA?

Year-to-date, the FMED ETF saw -$20M in flows, compared to +$1M for WDNA.

Which ETF is more volatile: FMED or WDNA?

Over the past year, FMED had a volatility of 24.11%, while WDNA experienced 28.98%.

Which ETF is bigger: FMED or WDNA?

As of November 5, 2026, FMED holds $47.38 M in assets under management (AUM), while WDNA manages $4.75 M.

What sectors do the FMED and WDNA ETFs invest in?

FMED leans toward sectors like Healthcare. Meanwhile, WDNA focuses on Healthcare.

What are the top holdings of the FMED ETF and WDNA ETF?

FMED top holdings include 10X Genomics, Inc., Natera, Inc. and Thermo Fisher Scientific, Inc.. WDNA holds in its top three: Moderna, Inc., Twist Bioscience Corp. and 10X Genomics, Inc..

FMEDvsWDNAETF Comparison

Fidelity Disruptive Medicine ETF

WisdomTree BioRevolution Fund

FMED vs WDNA performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the FMED and WDNA ETFs performed in 2026?

As of November 5, 2026, FMED is up 14.76% year-to-date (YTD), while WDNA has returned 33.87%. That puts WDNA better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or WDNA?

Year-to-date, the FMED ETF saw -$20M in flows, compared to +$1M for WDNA.

Which ETF is more volatile: FMED or WDNA?

Over the past year, FMED had a volatility of 24.11%, while WDNA experienced 28.98%.

Which ETF is bigger: FMED or WDNA?

As of November 5, 2026, FMED holds $47.38 M in assets under management (AUM), while WDNA manages $4.75 M.

What sectors do the FMED and WDNA ETFs invest in?

FMED leans toward sectors like Healthcare. Meanwhile, WDNA focuses on Healthcare.

What are the top holdings of the FMED ETF and WDNA ETF?

FMED top holdings include 10X Genomics, Inc., Natera, Inc. and Thermo Fisher Scientific, Inc.. WDNA holds in its top three: Moderna, Inc., Twist Bioscience Corp. and 10X Genomics, Inc..

Which ETF is more diversified: FMED or WDNA?

FMED holds 71 securities with 47.18% of its assets in the top 15. WDNA has 79 securities and a top 15 weight of 50.08%.

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