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FMEDvsPTHETF Comparison

ETF 1

FMED

Fidelity Disruptive Medicine ETF

This fund is part of

Multiple Trends

-6.5%

Full FMED fund page

VS

ETF 2

PTH

Invesco DWA Healthcare Momentum ETF

This fund is part of

US Health Care

-3.27%

Full PTH fund page

Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. Invesco DWA Healthcare Momentum ETF (PTH) is part of the US Health Care segment. FMED's top 1 sector exposures are Healthcare. In contrast, PTH's top sector exposures are Healthcare and Consumer Non-Cyclicals. FMED is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.72% for PTH. FMED is up 14.76% year-to-date (YTD) with -$20M in YTD flows. PTH performs worse with 13.21% YTD performance, and +$152M in YTD flows. Run a side-by-side ETF comparison of FMED and PTH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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FMED vs PTH performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 11/05/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	FMED PTH	-4.35%-8.16%	+7.81%-6.32%	+14.76%+13.21%	+19.85%+21.55%	+48.91%+86.20%	n/a+6.30%
Flows	FMED PTH	-$3M+$9M	-$3M+$58M	-$20M+$152M	-$18M+$162M	-$15M+$107M	--$101M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	FMED PTH	+31.58%+31.90%	+24.11%+28.10%	+20.23%+26.35%	n/a+26.16%
Max drawdown	FMED PTH	-7.63%-12.72%	-17.78%-12.72%	-19.20%-27.71%	n/a-46.99%
Max drawdown duration	FMED PTH	69d78d	212d78d	267d353d	n/a1620d

Trading data

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	FMED	PTH
Last sale 11/6/2026 at 2:30 PM		$57.44
Previous close 11/04/2026		$56.27
Consolidated volume 11/04/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of October 30, 2026

1-year trailing difference

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FMED

is actively managed and doesn’t replicate an index

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	FMED	PTH
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 11/6/2026 at 2:30 PM

Live

Closed

	FMED	PTH
Last price	–	$57.44
1D performance	–	+2.08%
AuM	$47.38 M	$280.85 M
E/R	0.5%	0.72%

Characteristics

	FMED	PTH
Management strategy	Active	Passive
Provider	Fidelity	Invesco
Benchmark	-	Dorsey Wright Healthcare Technical Leaders Index
N° of holdings	71	54
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 12, 2023	October 12, 2006
ESG	No	No

More FMED data on Trackinsight

More PTH data on Trackinsight

Exposure

Countries

FMED

USA

84.97%

Other

15.03%

PTH

USA

90.51%

Other

9.49%

Sectors

FMED

Healthcare

99.49%

Other

0.51%

PTH

Healthcare

99.23%

Other

0.77%

Diversification

FMED

Total weight of top 15 holdings out of 15

47.18%

PTH

Total weight of top 15 holdings out of 15

51.15%

Top 15 holdings

Data as of September 30, 2026

FMED

10X Genomics, Inc.

5.82%

Natera, Inc.

4.47%

Thermo Fisher Scientific, Inc.

4.19%

Danaher Corp.

3.92%

Illumina, Inc.

3.56%

argenx SE

2.96%

Lifestance Health Group, Inc.

2.87%

Revolution Medicines, Inc.

2.86%

Sartorius Stedim Biotech SA

2.72%

Moderna, Inc.

2.62%

Alnylam Pharmaceuticals, Inc.

2.48%

HeartFlow, Inc.

2.39%

Intuitive Surgical, Inc.

2.20%

Cogent Biosciences, Inc.

2.13%

Caris Life Sciences, Inc.

1.99%

PTH

Moderna, Inc.

6.40%

Guardant Health, Inc.

5.11%

Roivant Sciences Ltd.

5.06%

Revolution Medicines, Inc.

4.98%

10X Genomics, Inc.

3.99%

BrightSpring Health Services, Inc.

3.58%

Axsome Therapeutics, Inc.

3.44%

Twist Bioscience Corp.

2.92%

Illumina, Inc.

2.59%

Liquidia Corp.

2.47%

Oruka Therapeutics, Inc.

2.23%

Travere Therapeutics, Inc.

2.23%

Erasca, Inc.

2.15%

Replimune Group, Inc.

2.03%

Axogen, Inc.

1.98%

Frequently asked questions about FMED and PTH

How have the FMED and PTH ETFs performed in 2026?

As of November 5, 2026, FMED is up 14.76% year-to-date (YTD), while PTH has returned 13.21%. That puts FMED better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or PTH?

Year-to-date, the FMED ETF saw -$20M in flows, compared to +$152M for PTH.

Which ETF is more volatile: FMED or PTH?

Over the past year, FMED had a volatility of 24.11%, while PTH experienced 28.1%.

Which ETF is bigger: FMED or PTH?

As of November 5, 2026, FMED holds $47.38 M in assets under management (AUM), while PTH manages $280.85 M.

What sectors do the FMED and PTH ETFs invest in?

FMED leans toward sectors like Healthcare. Meanwhile, PTH focuses on Healthcare.

What are the top holdings of the FMED ETF and PTH ETF?

FMED top holdings include 10X Genomics, Inc., Natera, Inc. and Thermo Fisher Scientific, Inc.. PTH holds in its top three: Moderna, Inc., Guardant Health, Inc. and Roivant Sciences Ltd..

Which ETF is more diversified: FMED or PTH?

FMED holds 71 securities with 47.18% of its assets in the top 15. PTH has 54 securities and a top 15 weight of 51.15%.

Continued tightening of the U.S. labor market

September 23, 2022

PTH

FMEDvsPTHETF Comparison

Fidelity Disruptive Medicine ETF

Invesco DWA Healthcare Momentum ETF

FMED vs PTH performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the FMED and PTH ETFs performed in 2026?

As of November 5, 2026, FMED is up 14.76% year-to-date (YTD), while PTH has returned 13.21%. That puts FMED better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or PTH?

Year-to-date, the FMED ETF saw -$20M in flows, compared to +$152M for PTH.

Which ETF is more volatile: FMED or PTH?

Over the past year, FMED had a volatility of 24.11%, while PTH experienced 28.1%.

Which ETF is bigger: FMED or PTH?

As of November 5, 2026, FMED holds $47.38 M in assets under management (AUM), while PTH manages $280.85 M.

What sectors do the FMED and PTH ETFs invest in?

FMED leans toward sectors like Healthcare. Meanwhile, PTH focuses on Healthcare.

What are the top holdings of the FMED ETF and PTH ETF?

FMED top holdings include 10X Genomics, Inc., Natera, Inc. and Thermo Fisher Scientific, Inc.. PTH holds in its top three: Moderna, Inc., Guardant Health, Inc. and Roivant Sciences Ltd..

Which ETF is more diversified: FMED or PTH?

FMED holds 71 securities with 47.18% of its assets in the top 15. PTH has 54 securities and a top 15 weight of 51.15%.

Continued tightening of the U.S. labor market

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