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FMEDvsIBBQETF Comparison

ETF 1
FMED

Fidelity Disruptive Medicine ETF

This fund is part of
Multiple Trends
-0.43%
Full FMED fund page
VS
ETF 2
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-1.6%
Full IBBQ fund page

Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. FMED is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.19% for IBBQ. FMED is down -10.31% year-to-date (YTD) with - in YTD flows. IBBQ performs better with -0.7% YTD performance, and +$8M in YTD flows. Run a side-by-side ETF comparison of FMED and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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FMED vs IBBQ performance and flow charts

Performance

-8.0-6.0-4.0-2.00.02.0%Feb 18Feb 25Mar 4Mar 11Mar 18

Cumulative Flows

Feb 18Feb 25Mar 4Mar 11Mar 18

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Historic performance and flows
Data as of 03/18/2026
1M3MYTD1Y3Y5Y
Perf.
FMED
IBBQ
-6.92%-5.53%
-10.09%+1.14%
-10.31%-0.70%
-0.32%+28.29%
n/a+43.75%
n/an/a
Flows
FMED
IBBQ
--
-+$11M
-+$8M
+$5M+$21M
-+$47M
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
FMED
IBBQ
+19.28%+21.07%
+19.99%+23.16%
n/a+19.31%
n/an/a
Max drawdown
FMED
IBBQ
-14.72%-6.55%
-15.97%-17.05%
n/a-23.78%
n/an/a
Max drawdown duration
FMED
IBBQ
55d22d
108d120d
n/a375d
n/an/a
Trading data

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FMED
IBBQ
Last sale
3/18/2026 at 1:30 PM
$24.30
$28.18
Previous close
03/18/2026
$24.77
$28.75
Consolidated volume
03/18/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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FMED
is actively managed and doesn’t replicate an index

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FMED
IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/18/2026 at 1:30 PM
Live
Closed
FMED
IBBQ
Last price
$24.30
$28.18
1D performance
-1.91%
-1.98%
AuM$56.47 M$71.02 M
E/R0.5%0.19%
Characteristics
FMED
IBBQ
Management strategyActivePassive
ProviderFidelityInvesco
Benchmark-NASDAQ Biotechnology Index
N° of holdings50196
Asset class-Equities
Trailing 12m distribution yield
Join
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Inception dateJune 12, 2023June 9, 2021
ESGNoNo
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Exposure

Countries

FMED
USA
89.2%
Other
10.8%
IBBQ
USA
93.84%
Other
6.16%

Sectors

FMED
Health Care
82.23%
Other
17.77%
IBBQ
Health Care
85.82%
Other
14.18%

Diversification

FMED

Total weight of top 15 holdings out of 15

47.79%
IBBQ

Total weight of top 15 holdings out of 15

52.08%

Top 15 holdings

Data as of January 31, 2026
FMED
BOSTON SCIENTIFIC
4.76%
DANAHER
4.37%
US04016X1019
4.08%
UCB
3.98%
COGENT BIOSCIENCES
3.65%
VEEVA SYSTEMS IN
3.45%
PENUMBRA
3.38%
ALNYLAM PHARMACEUTICALS
3.35%
INTUITIVE SURGICAL
2.81%
US9467841055
2.63%
INSULET
2.61%
LIFESTANCE HEALTH GROUP
2.33%
EDWARDS LIFESCIENCES
2.26%
MODERNA INC
2.10%
STEDIM
2.06%
IBBQ
VERTEX PHARMACEUTICALS
8.96%
GILEAD SCIENCES
8.92%
AMGEN-T
8.25%
REGENERON PHARMACEUTICALS
5.90%
ALNYLAM PHARMACEUTICALS
3.58%
INSMED
2.55%
BIOGEN INC
1.90%
US04016X1019
1.82%
ILLUMINA
1.75%
UTD THERAPEUT
1.53%
INCYTE
1.51%
REVOLUTION MEDICINES INC
1.42%
MODERNA INC
1.41%
ROYALTY PHARMA
1.30%
MEDPACE HOLDINGS INC
1.27%
Frequently asked questions about FMED and IBBQ

How have the FMED and IBBQ ETFs performed in 2026?

As of March 18, 2026, FMED is down -10.31% year-to-date (YTD), while IBBQ has lost -0.7%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or IBBQ?

Year-to-date, the FMED ETF saw - in flows, compared to +$8M for IBBQ.

Which ETF is more volatile: FMED or IBBQ?

Over the past year, FMED had a volatility of 19.99%, while IBBQ experienced 23.16%.

Which ETF is bigger: FMED or IBBQ?

As of March 18, 2026, FMED holds $56.47 M in assets under management (AUM), while IBBQ manages $71.02 M.

What sectors do the FMED and IBBQ ETFs invest in?

FMED leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the FMED ETF and IBBQ ETF?

FMED top holdings include BOSTON SCIENTIFIC, DANAHER and US04016X1019. IBBQ holds in its top three: VERTEX PHARMACEUTICALS, GILEAD SCIENCES and AMGEN-T.

Which ETF is more diversified: FMED or IBBQ?

FMED holds 65 securities with 47.79% of its assets in the top 15. IBBQ has 262 securities and a top 15 weight of 52.08%.

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