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FMEDvsEKGETF Comparison

ETF 1
FMED

Fidelity Disruptive Medicine ETF

This fund is part of
Multiple Trends
+2.93%
VS
ETF 2
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
+0.09%

Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) is part of the Healthcare Technology segment. Both ETFs have the same top 1 sector exposures: Healthcare. FMED is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.65% for EKG. FMED is up 17.43% year-to-date (YTD) with -$17M in YTD flows. EKG performs better with 19.85% YTD performance, and +$963K in YTD flows. Run a side-by-side ETF comparison of FMED and EKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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FMED vs EKG performance and flow charts

Performance

-50510%Aug 18Aug 25Sep 1Sep 9Sep 16

Cumulative Flows

Aug 18Aug 25Sep 1Sep 9Sep 16

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Historic performance and flows
Data as of 09/21/2026
1M3MYTD1Y3Y5Y
Perf.
FMED
EKG
-2.40%+8.96%
+21.48%+28.77%
+17.43%+19.85%
+29.04%+28.94%
+43.82%+54.23%
n/an/a
Flows
FMED
EKG
--
-+$963K
-$17M+$963K
-$14M+$963K
-$3M+$2M
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
FMED
EKG
+24.66%+26.13%
+21.06%+23.61%
+19.25%+23.89%
n/an/a
Max drawdown
FMED
EKG
-7.15%-7.45%
-17.78%-22.11%
-19.20%-24.32%
n/an/a
Max drawdown duration
FMED
EKG
29d28d
212d208d
267d264d
n/an/a
Trading data

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FMED
EKG
Last sale
9/22/2026 at 1:30 PM
$23.21
Previous close
09/21/2026
$22.94
Consolidated volume
09/21/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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FMED
is actively managed and doesn’t replicate an index

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FMED
EKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 9/22/2026 at 1:30 PM
Live
Closed
FMED
EKG
Last price
$23.21
1D performance
+1.19%
AuM$51.66 M$4.55 M
E/R0.5%0.65%
Characteristics
FMED
EKG
Management strategyActivePassive
ProviderFidelityFirst Trust
Benchmark-Nasdaq Lux Health Tech Index
N° of holdings7437
Asset class-Equities
Trailing 12m distribution yield
Join
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Inception dateJune 12, 2023March 22, 2022
ESGNoNo
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Exposure

Countries

FMED
USA
83.4%
Other
16.6%
EKG
USA
95.72%
Other
4.28%

Sectors

FMED
Healthcare
100%
Other
0%
EKG
Healthcare
98.67%
Other
1.33%
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Diversification

FMED

Total weight of top 15 holdings out of 15

43.09%
EKG

Total weight of top 15 holdings out of 15

74.55%

Top 15 holdings

Data as of July 31, 2026
FMED
10X Genomics, Inc.
4.48%
Thermo Fisher Scientific, Inc.
3.98%
Danaher Corp.
3.86%
Lifestance Health Group, Inc.
3.15%
Alnylam Pharmaceuticals, Inc.
3.10%
argenx SE
2.99%
Cogent Biosciences, Inc.
2.98%
Revolution Medicines, Inc.
2.85%
Illumina, Inc.
2.62%
Intuitive Surgical, Inc.
2.34%
Kymera Therapeutics, Inc.
2.29%
UnitedHealth Group, Inc.
2.24%
Ascendis Pharma A/S
2.12%
Kiniksa Pharmaceuticals International Plc
2.06%
UCB SA
2.03%
EKG
IQVIA Holdings, Inc.
9.37%
Veeva Systems, Inc.
9.01%
DexCom, Inc.
8.04%
Guardant Health, Inc.
5.85%
ResMed, Inc.
5.83%
Illumina, Inc.
5.19%
Natera, Inc.
5.11%
Intuitive Surgical, Inc.
4.87%
Oscar Health, Inc.
3.90%
Tempus AI, Inc.
3.64%
QIAGEN NV
2.95%
Globus Medical, Inc.
2.94%
Align Technology, Inc.
2.74%
10X Genomics, Inc.
2.57%
Hims & Hers Health, Inc.
2.54%
Frequently asked questions about FMED and EKG

How have the FMED and EKG ETFs performed in 2026?

As of September 21, 2026, FMED is up 17.43% year-to-date (YTD), while EKG has returned 19.85%. That puts EKG better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or EKG?

Year-to-date, the FMED ETF saw -$17M in flows, compared to +$963K for EKG.

Which ETF is more volatile: FMED or EKG?

Over the past year, FMED had a volatility of 21.06%, while EKG experienced 23.61%.

Which ETF is bigger: FMED or EKG?

As of September 21, 2026, FMED holds $51.66 M in assets under management (AUM), while EKG manages $4.55 M.

What sectors do the FMED and EKG ETFs invest in?

FMED leans toward sectors like Healthcare. Meanwhile, EKG focuses on Healthcare.

What are the top holdings of the FMED ETF and EKG ETF?

FMED top holdings include 10X Genomics, Inc., Thermo Fisher Scientific, Inc. and Danaher Corp.. EKG holds in its top three: IQVIA Holdings, Inc., Veeva Systems, Inc. and DexCom, Inc..

Which ETF is more diversified: FMED or EKG?

FMED holds 74 securities with 43.09% of its assets in the top 15. EKG has 37 securities and a top 15 weight of 74.55%.

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