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FMEDvsEKGETF Comparison

ETF 1
FMED

Fidelity Disruptive Medicine ETF

This fund is part of
Multiple Trends
+1.26%
VS
ETF 2
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
+0.11%

Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) is part of the Healthcare Technology segment. Both ETFs have the same top 1 sector exposures: Healthcare. FMED is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.65% for EKG. FMED is up 18.54% year-to-date (YTD) with -$17M in YTD flows. EKG performs better with 23.53% YTD performance, and +$6M in YTD flows. Run a side-by-side ETF comparison of FMED and EKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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FMED vs EKG performance and flow charts

Performance

-4.0-2.00.02.04.06.08.0%Oct 2Oct 9Oct 16Oct 23Oct 30

Cumulative Flows

0 M0.2 M0.4 M0.6 M0.8 M1 M1.2 MOct 2Oct 9Oct 16Oct 23Oct 30

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Historic performance and flows
Data as of 11/03/2026
1M3MYTD1Y3Y5Y
Perf.
FMED
EKG
-1.20%+0.50%
+14.01%+17.26%
+18.54%+23.53%
+23.05%+26.51%
+52.71%+84.70%
n/an/a
Flows
FMED
EKG
-+$1M
-+$5M
-$17M+$6M
-$14M+$6M
-$12M+$7M
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
FMED
EKG
+28.56%+27.52%
+23.08%+24.94%
+19.85%+23.98%
n/an/a
Max drawdown
FMED
EKG
-7.63%-6.18%
-17.78%-22.11%
-19.20%-24.32%
n/an/a
Max drawdown duration
FMED
EKG
69d4d
212d208d
267d264d
n/an/a
Trading data

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FMED
EKG
Last sale
11/3/2026 at 2:30 PM
$23.71
Previous close
11/03/2026
$23.46
Consolidated volume
11/03/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of October 30, 2026
1-year trailing difference

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FMED
is actively managed and doesn’t replicate an index

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FMED
EKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 11/3/2026 at 2:30 PM
Live
Closed
FMED
EKG
Last price
–
$23.71
1D performance
–
+1.07%
AuM$52.15 M$9.39 M
E/R0.5%0.65%
Characteristics
FMED
EKG
Management strategyActivePassive
ProviderFidelityFirst Trust
Benchmark-Nasdaq Lux Health Tech Index
N° of holdings7151
Asset class-Equities
Trailing 12m distribution yield
Join
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Inception dateJune 12, 2023March 22, 2022
ESGNoNo
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Exposure

Countries

FMED
USA
84.97%
Other
15.03%
EKG
USA
96.91%
Other
3.09%

Sectors

FMED
Healthcare
99.49%
Other
0.51%
EKG
Healthcare
99.9%
Other
0.1%
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Diversification

FMED

Total weight of top 15 holdings out of 15

47.18%
EKG

Total weight of top 15 holdings out of 15

72.5%

Top 15 holdings

Data as of September 30, 2026
FMED
10X Genomics, Inc.
5.82%
Natera, Inc.
4.47%
Thermo Fisher Scientific, Inc.
4.19%
Danaher Corp.
3.92%
Illumina, Inc.
3.56%
argenx SE
2.96%
Lifestance Health Group, Inc.
2.87%
Revolution Medicines, Inc.
2.86%
Sartorius Stedim Biotech SA
2.72%
Moderna, Inc.
2.62%
Alnylam Pharmaceuticals, Inc.
2.48%
HeartFlow, Inc.
2.39%
Intuitive Surgical, Inc.
2.20%
Cogent Biosciences, Inc.
2.13%
Caris Life Sciences, Inc.
1.99%
EKG
Natera, Inc.
9.62%
Intuitive Surgical, Inc.
8.07%
IQVIA Holdings, Inc.
7.56%
Veeva Systems, Inc.
7.47%
DexCom, Inc.
7.18%
Illumina, Inc.
4.71%
Guardant Health, Inc.
4.16%
ResMed, Inc.
3.48%
Globus Medical, Inc.
3.21%
Tempus AI, Inc.
3.06%
QIAGEN NV
2.99%
Twist Bioscience Corp.
2.85%
Align Technology, Inc.
2.75%
Insulet Corp.
2.73%
Oscar Health, Inc.
2.66%
Frequently asked questions about FMED and EKG

How have the FMED and EKG ETFs performed in 2026?

As of November 3, 2026, FMED is up 18.54% year-to-date (YTD), while EKG has returned 23.53%. That puts EKG better performer ahead so far this year.

Which ETF is attracting more investor money: FMED or EKG?

Year-to-date, the FMED ETF saw -$17M in flows, compared to +$6M for EKG.

Which ETF is more volatile: FMED or EKG?

Over the past year, FMED had a volatility of 23.08%, while EKG experienced 24.94%.

Which ETF is bigger: FMED or EKG?

As of November 3, 2026, FMED holds $52.15 M in assets under management (AUM), while EKG manages $9.39 M.

What sectors do the FMED and EKG ETFs invest in?

FMED leans toward sectors like Healthcare. Meanwhile, EKG focuses on Healthcare.

What are the top holdings of the FMED ETF and EKG ETF?

FMED top holdings include 10X Genomics, Inc., Natera, Inc. and Thermo Fisher Scientific, Inc.. EKG holds in its top three: Natera, Inc., Intuitive Surgical, Inc. and IQVIA Holdings, Inc..

Which ETF is more diversified: FMED or EKG?

FMED holds 71 securities with 47.18% of its assets in the top 15. EKG has 51 securities and a top 15 weight of 72.5%.

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