FMEDvsBBPETF Comparison
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Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. Virtus LifeSci Biotech Products ETF (BBP) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 1 sector exposures: Healthcare. FMED is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.34% for BBP. FMED is up 14.76% year-to-date (YTD) with -$20M in YTD flows. BBP performs better with 32.64% YTD performance, and +$71M in YTD flows. Run a side-by-side ETF comparison of FMED and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FMED vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 11/05/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FMED BBP | -4.35%+2.39% | +7.81%+10.11% | +14.76%+32.64% | +19.85%+44.91% | +48.91%+116.39% | n/a+95.63% |
| Flows | FMED BBP | -$3M+$5M | -$3M+$26M | -$20M+$71M | -$18M+$83M | -$15M+$89M | -+$81M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FMED BBP | +31.58%+28.64% | +24.11%+26.65% | +20.23%+24.95% | n/a+26.86% |
| Max drawdown | FMED BBP | -7.63%-8.70% | -17.78%-9.59% | -19.20%-25.54% | n/a-36.66% |
| Max drawdown duration | FMED BBP | 69d77d | 212d48d | 267d292d | n/a551d |
Trading data
FMED | BBP | |
Last sale 11/6/2026 at 2:30 PM | $102.32 | |
| Previous close 11/04/2026 | $100.78 | |
| Consolidated volume 11/04/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of October 30, 2026
1-year trailing difference
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FMED
is actively managed and doesn’t replicate an indexFMED | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 11/6/2026 at 2:30 PM
Live
Closed
FMED | BBP | |
|---|---|---|
| Last price | – | $102.32 |
| 1D performance | – | +1.52% |
| AuM | $47.38 M | $137.54 M |
| E/R | 0.5% | 0.34% |
Characteristics
FMED | BBP | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Fidelity | VIRTUS Investment Partners |
| Benchmark | - | LifeSci Biotechnology Products Index |
| N° of holdings | 71 | 64 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 12, 2023 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
FMED
USA
84.97%
Other
15.03%
BBP
USA
85.84%
Other
14.16%
Sectors
FMED
Healthcare
99.49%
Other
0.51%
BBP
Healthcare
98.4%
Other
1.6%
Diversification
FMED
Total weight of top 15 holdings out of 15
47.18%
BBP
Total weight of top 15 holdings out of 15
33.98%
Top 15 holdings
Data as of September 30, 2026
FMED
10X Genomics, Inc.
5.82%
Natera, Inc.
4.47%
Thermo Fisher Scientific, Inc.
4.19%
Danaher Corp.
3.92%
Illumina, Inc.
3.56%
argenx SE
2.96%
Lifestance Health Group, Inc.
2.87%
Revolution Medicines, Inc.
2.86%
Sartorius Stedim Biotech SA
2.72%
Moderna, Inc.
2.62%
Alnylam Pharmaceuticals, Inc.
2.48%
HeartFlow, Inc.
2.39%
Intuitive Surgical, Inc.
2.20%
Cogent Biosciences, Inc.
2.13%
Caris Life Sciences, Inc.
1.99%
BBP
Moderna, Inc.
5.14%
Iovance Biotherapeutics, Inc.
3.48%
Omeros Corp.
2.96%
Verastem, Inc.
2.43%
Precigen, Inc.
2.25%
Halozyme Therapeutics, Inc.
2.11%
Rigel Pharmaceuticals, Inc.
1.89%
Zai Lab Ltd.
1.89%
Kiniksa Pharmaceuticals International Plc
1.87%
BeOne Medicines Ltd.
1.76%
Xeris Biopharma Holdings, Inc.
1.73%
Protagonist Therapeutics, Inc.
1.67%
Regeneron Pharmaceuticals, Inc.
1.66%
Tarsus Pharmaceuticals, Inc.
1.58%
Sarepta Therapeutics, Inc.
1.57%
Frequently asked questions about FMED and BBP
How have the FMED and BBP ETFs performed in 2026?
As of November 5, 2026, FMED is up 14.76% year-to-date (YTD), while BBP has returned 32.64%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: FMED or BBP?
Year-to-date, the FMED ETF saw -$20M in flows, compared to +$71M for BBP.
Which ETF is more volatile: FMED or BBP?
Over the past year, FMED had a volatility of 24.11%, while BBP experienced 26.65%.
Which ETF is bigger: FMED or BBP?
As of November 5, 2026, FMED holds $47.38 M in assets under management (AUM), while BBP manages $137.54 M.
What sectors do the FMED and BBP ETFs invest in?
FMED leans toward sectors like Healthcare. Meanwhile, BBP focuses on Healthcare.
What are the top holdings of the FMED ETF and BBP ETF?
FMED top holdings include 10X Genomics, Inc., Natera, Inc. and Thermo Fisher Scientific, Inc.. BBP holds in its top three: Moderna, Inc., Iovance Biotherapeutics, Inc. and Omeros Corp..
Which ETF is more diversified: FMED or BBP?
FMED holds 71 securities with 47.18% of its assets in the top 15. BBP has 64 securities and a top 15 weight of 33.98%.
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