FMEDvsBBPETF Comparison
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Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. Virtus LifeSci Biotech Products ETF (BBP) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 1 sector exposures: Healthcare. FMED is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.34% for BBP. FMED is up 17.43% year-to-date (YTD) with -$17M in YTD flows. BBP performs better with 31.78% YTD performance, and +$61M in YTD flows. Run a side-by-side ETF comparison of FMED and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FMED vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/21/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FMED BBP | -2.40%-2.09% | +21.48%+14.77% | +17.43%+31.78% | +29.04%+49.16% | +43.82%+111.25% | n/a+100.52% |
| Flows | FMED BBP | -+$16M | -+$31M | -$17M+$61M | -$14M+$72M | -$3M+$78M | -+$71M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FMED BBP | +24.66%+26.46% | +21.06%+25.30% | +19.25%+24.78% | n/a+26.64% |
| Max drawdown | FMED BBP | -7.15%-9.34% | -17.78%-9.59% | -19.20%-25.54% | n/a-37.61% |
| Max drawdown duration | FMED BBP | 29d39d | 212d48d | 267d292d | n/a586d |
Trading data
FMED | BBP | |
Last sale 9/22/2026 at 1:30 PM | $107.66 | |
| Previous close 09/21/2026 | $105.21 | |
| Consolidated volume 09/21/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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FMED
is actively managed and doesn’t replicate an indexFMED | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/22/2026 at 1:30 PM
Live
Closed
FMED | BBP | |
|---|---|---|
| Last price | – | $107.66 |
| 1D performance | – | +2.33% |
| AuM | $51.66 M | $126.13 M |
| E/R | 0.5% | 0.34% |
Characteristics
FMED | BBP | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Fidelity | VIRTUS Investment Partners |
| Benchmark | - | LifeSci Biotechnology Products Index |
| N° of holdings | 74 | 66 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 12, 2023 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
FMED
USA
83.4%
Other
16.6%
BBP
USA
86.5%
Other
13.5%
Sectors
FMED
Healthcare
100%
Other
0%
BBP
Healthcare
98.2%
Other
1.8%
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Diversification
FMED
Total weight of top 15 holdings out of 15
43.09%
BBP
Total weight of top 15 holdings out of 15
26.78%
Top 15 holdings
Data as of July 31, 2026
FMED
10X Genomics, Inc.
4.48%
Thermo Fisher Scientific, Inc.
3.98%
Danaher Corp.
3.86%
Lifestance Health Group, Inc.
3.15%
Alnylam Pharmaceuticals, Inc.
3.10%
argenx SE
2.99%
Cogent Biosciences, Inc.
2.98%
Revolution Medicines, Inc.
2.85%
Illumina, Inc.
2.62%
Intuitive Surgical, Inc.
2.34%
Kymera Therapeutics, Inc.
2.29%
UnitedHealth Group, Inc.
2.24%
Ascendis Pharma A/S
2.12%
Kiniksa Pharmaceuticals International Plc
2.06%
UCB SA
2.03%
BBP
Crinetics Pharmaceuticals, Inc.
3.24%
Verastem, Inc.
1.98%
Nuvation Bio, Inc.
1.80%
Omeros Corp.
1.73%
Geron Corp.
1.72%
BridgeBio Pharma, Inc.
1.68%
Agios Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
BeOne Medicines Ltd.
1.64%
Kiniksa Pharmaceuticals International Plc
1.63%
Precigen, Inc.
1.62%
Xeris Biopharma Holdings, Inc.
1.61%
ACADIA Pharmaceuticals, Inc.
1.60%
Iovance Biotherapeutics, Inc.
1.60%
Rhythm Pharmaceuticals, Inc.
1.60%
Frequently asked questions about FMED and BBP
How have the FMED and BBP ETFs performed in 2026?
As of September 21, 2026, FMED is up 17.43% year-to-date (YTD), while BBP has returned 31.78%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: FMED or BBP?
Year-to-date, the FMED ETF saw -$17M in flows, compared to +$61M for BBP.
Which ETF is more volatile: FMED or BBP?
Over the past year, FMED had a volatility of 21.06%, while BBP experienced 25.3%.
Which ETF is bigger: FMED or BBP?
As of September 21, 2026, FMED holds $51.66 M in assets under management (AUM), while BBP manages $126.13 M.
What sectors do the FMED and BBP ETFs invest in?
FMED leans toward sectors like Healthcare. Meanwhile, BBP focuses on Healthcare.
What are the top holdings of the FMED ETF and BBP ETF?
FMED top holdings include 10X Genomics, Inc., Thermo Fisher Scientific, Inc. and Danaher Corp.. BBP holds in its top three: Crinetics Pharmaceuticals, Inc., Verastem, Inc. and Nuvation Bio, Inc..
Which ETF is more diversified: FMED or BBP?
FMED holds 74 securities with 43.09% of its assets in the top 15. BBP has 66 securities and a top 15 weight of 26.78%.
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