FMEDvsARKGETF Comparison
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Fidelity Disruptive Medicine ETF (FMED) belongs to the Multiple Trends segment. ARK Genomic Revolution ETF (ARKG) is part of the BioTech & Genomics segment. Both ETFs have the same top 1 sector exposures: Healthcare. FMED is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.75% for ARKG. FMED is up 19.11% year-to-date (YTD) with -$17M in YTD flows. ARKG performs better with 81.09% YTD performance, and +$130M in YTD flows. Run a side-by-side ETF comparison of FMED and ARKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FMED vs ARKG performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/22/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FMED ARKG | -0.02%+10.18% | +23.23%+45.14% | +19.11%+81.09% | +30.90%+89.92% | +46.80%+89.53% | n/a-34.11% |
| Flows | FMED ARKG | -+$110M | -+$178M | -$17M+$130M | -$14M+$150M | -$12M-$383M | --$2.06B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FMED ARKG | +24.56%+43.70% | +21.06%+44.23% | +19.27%+44.15% | n/a+46.45% |
| Max drawdown | FMED ARKG | -7.15%-13.89% | -17.78%-27.52% | -19.20%-46.41% | n/a-77.32% |
| Max drawdown duration | FMED ARKG | 29d32d | 212d126d | 267d882d | n/a1825d |
Trading data
FMED | ARKG | |
Last sale 9/23/2026 at 1:30 PM | $50.92 | |
| Previous close 09/22/2026 | $52.87 | |
| Consolidated volume 09/22/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 9/23/2026 at 1:30 PM
Live
Closed
FMED | ARKG | |
|---|---|---|
| Last price | – | $50.92 |
| 1D performance | – | -3.69% |
| AuM | $52.40 M | $2.22 B |
| E/R | 0.5% | 0.75% |
Characteristics
FMED | ARKG | |
|---|---|---|
| Management strategy | Active | Active |
| Provider | Fidelity | Ark Investment |
| Benchmark | - | - |
| N° of holdings | 74 | 31 |
| Asset class | - | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 12, 2023 | April 2, 2019 |
| ESG | No | No |
Exposure
Countries
FMED
USA
83.4%
Other
16.6%
ARKG
USA
88.43%
Other
11.57%
Sectors
FMED
Healthcare
100%
Other
0%
ARKG
Healthcare
97.99%
Other
2.01%
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Diversification
FMED
Total weight of top 15 holdings out of 15
43.09%
ARKG
Total weight of top 15 holdings out of 15
75.55%
Top 15 holdings
Data as of July 31, 2026
FMED
10X Genomics, Inc.
4.48%
Thermo Fisher Scientific, Inc.
3.98%
Danaher Corp.
3.86%
Lifestance Health Group, Inc.
3.15%
Alnylam Pharmaceuticals, Inc.
3.10%
argenx SE
2.99%
Cogent Biosciences, Inc.
2.98%
Revolution Medicines, Inc.
2.85%
Illumina, Inc.
2.62%
Intuitive Surgical, Inc.
2.34%
Kymera Therapeutics, Inc.
2.29%
UnitedHealth Group, Inc.
2.24%
Ascendis Pharma A/S
2.12%
Kiniksa Pharmaceuticals International Plc
2.06%
UCB SA
2.03%
ARKG
10X Genomics, Inc.
9.41%
Twist Bioscience Corp.
7.74%
Tempus AI, Inc.
6.57%
CRISPR Therapeutics AG
6.30%
Personalis, Inc.
5.48%
Absci Corp.
5.15%
Guardant Health, Inc.
4.75%
Illumina, Inc.
4.75%
Eli Lilly & Co.
4.69%
CareDx, Inc.
4.31%
Natera, Inc.
4.14%
Beam Therapeutics, Inc.
3.78%
Compass Pathways Plc
3.26%
Recursion Pharmaceuticals, Inc.
2.63%
Adaptive Biotechnologies Corp.
2.58%
Frequently asked questions about FMED and ARKG
How have the FMED and ARKG ETFs performed in 2026?
As of September 22, 2026, FMED is up 19.11% year-to-date (YTD), while ARKG has returned 81.09%. That puts ARKG better performer ahead so far this year.
Which ETF is attracting more investor money: FMED or ARKG?
Year-to-date, the FMED ETF saw -$17M in flows, compared to +$130M for ARKG.
Which ETF is more volatile: FMED or ARKG?
Over the past year, FMED had a volatility of 21.06%, while ARKG experienced 44.23%.
Which ETF is bigger: FMED or ARKG?
As of September 22, 2026, FMED holds $52.40 M in assets under management (AUM), while ARKG manages $2.22 B.
What sectors do the FMED and ARKG ETFs invest in?
FMED leans toward sectors like Healthcare. Meanwhile, ARKG focuses on Healthcare.
What are the top holdings of the FMED ETF and ARKG ETF?
FMED top holdings include 10X Genomics, Inc., Thermo Fisher Scientific, Inc. and Danaher Corp.. ARKG holds in its top three: 10X Genomics, Inc., Twist Bioscience Corp. and Tempus AI, Inc..
Which ETF is more diversified: FMED or ARKG?
FMED holds 74 securities with 43.09% of its assets in the top 15. ARKG has 31 securities and a top 15 weight of 75.55%.
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Latest news about FMED & ARKG
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