FBTvsIBBQETF Comparison
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First Trust NYSE Arca Biotechnology Index Fund ETF (FBT) and Invesco Nasdaq Biotechnology ETF (IBBQ) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Healthcare. FBT is more expensive with a Total Expense Ratio (TER) of 0.54%, versus 0.19% for IBBQ. FBT is up 21.59% year-to-date (YTD) with +$976M in YTD flows. IBBQ performs worse with 15.4% YTD performance, and +$3M in YTD flows. Run a side-by-side ETF comparison of FBT and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FBT vs IBBQ performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/29/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FBT IBBQ | +1.05%+0.10% | +24.74%+12.21% | +21.59%+15.40% | +50.68%+46.91% | +62.12%+62.42% | +49.66%+32.40% |
| Flows | FBT IBBQ | -$147M+$4M | -$95M+$3M | +$976M+$3M | +$1.03B+$23M | +$584M+$39M | +$244M+$11M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FBT IBBQ | +21.62%+22.34% | +21.24%+20.29% | +20.64%+20.25% | +22.13%+21.96% |
| Max drawdown | FBT IBBQ | -4.37%-5.97% | -14.27%-8.38% | -19.92%-23.78% | -29.91%-38.09% |
| Max drawdown duration | FBT IBBQ | 22d23d | 126d48d | 237d375d | 1159d1543d |
Trading data
FBT | IBBQ | |
Last sale 7/30/2026 at 1:30 PM | $252.66 | $32.70 |
| Previous close 07/30/2026 | $250.47 | $32.41 |
| Consolidated volume 07/30/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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FBT | IBBQ | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/30/2026 at 1:30 PM
Live
Closed
FBT | IBBQ | |
|---|---|---|
| Last price | $252.66 | $32.70 |
| 1D performance | +0.87% | +0.90% |
| AuM | $2.74 B | $76.45 M |
| E/R | 0.54% | 0.19% |
Characteristics
FBT | IBBQ | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | Invesco |
| Benchmark | NYSE Arca Biotechnology Index | NASDAQ Biotechnology Index |
| N° of holdings | 30 | 251 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 19, 2006 | June 9, 2021 |
| ESG | No | No |
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Exposure
Countries
FBT
USA
84.94%
Other
15.06%
IBBQ
USA
88.1%
Other
11.9%
Sectors
FBT
Healthcare
99.93%
Other
0.07%
IBBQ
Healthcare
99.98%
Other
0.02%
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Diversification
FBT
Total weight of top 15 holdings out of 15
59.85%
IBBQ
Total weight of top 15 holdings out of 15
49.38%
Top 15 holdings
Data as of June 30, 2026
FBT
Corcept Therapeutics, Inc.
5.66%
NeoGenomics, Inc.
5.22%
Veracyte, Inc.
5.16%
Bruker Corp.
4.33%
Alkermes Plc
4.16%
Illumina, Inc.
4.08%
Krystal Biotech, Inc.
3.85%
Natera, Inc.
3.84%
Axsome Therapeutics, Inc.
3.62%
Neurocrine Biosciences, Inc.
3.49%
Bio-Techne Corp.
3.43%
Arrowhead Pharmaceuticals, Inc.
3.31%
Exelixis, Inc.
3.27%
Biogen, Inc.
3.25%
Incyte Corp.
3.18%
IBBQ
Vertex Pharmaceuticals, Inc.
8.16%
Amgen, Inc.
7.91%
Gilead Sciences, Inc.
7.07%
Regeneron Pharmaceuticals, Inc.
4.62%
Alnylam Pharmaceuticals, Inc.
2.76%
Revolution Medicines, Inc.
2.74%
Biogen, Inc.
2.26%
Illumina, Inc.
1.89%
Moderna, Inc.
1.89%
Royalty Pharma Plc
1.77%
Roivant Sciences Ltd.
1.74%
argenx SE
1.73%
United Therapeutics Corp.
1.63%
Incyte Corp.
1.61%
Insmed, Inc.
1.59%
Frequently asked questions about FBT and IBBQ
How have the FBT and IBBQ ETFs performed in 2026?
As of July 29, 2026, FBT is up 21.59% year-to-date (YTD), while IBBQ has returned 15.4%. That puts FBT better performer ahead so far this year.
Which ETF is attracting more investor money: FBT or IBBQ?
Year-to-date, the FBT ETF saw +$976M in flows, compared to +$3M for IBBQ.
Which ETF is more volatile: FBT or IBBQ?
Over the past year, FBT had a volatility of 21.24%, while IBBQ experienced 20.29%.
Which ETF is bigger: FBT or IBBQ?
As of July 29, 2026, FBT holds $2.74 B in assets under management (AUM), while IBBQ manages $76.45 M.
What sectors do the FBT and IBBQ ETFs invest in?
FBT leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.
What are the top holdings of the FBT ETF and IBBQ ETF?
FBT top holdings include Corcept Therapeutics, Inc., NeoGenomics, Inc. and Veracyte, Inc.. IBBQ holds in its top three: Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: FBT or IBBQ?
FBT holds 30 securities with 59.85% of its assets in the top 15. IBBQ has 251 securities and a top 15 weight of 49.38%.
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Latest news about FBT & IBBQ
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