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EKGvsPBEETF Comparison

ETF 1
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
-0.09%
VS
ETF 2
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
-0.45%

First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) belongs to the Healthcare Technology segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Healthcare. EKG is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.58% for PBE. EKG is up 2.83% year-to-date (YTD) with +$963K in YTD flows. PBE performs better with 10.18% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of EKG and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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EKG vs PBE performance and flow charts

Performance

-2.00.02.04.06.0%Jun 30Jul 7Jul 14Jul 21Jul 28

Cumulative Flows

0 M1 M2 M3 M4 M5 MJun 30Jul 7Jul 14Jul 21Jul 28

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Historic performance and flows
Data as of 07/30/2026
1M3MYTD1Y3Y5Y
Perf.
EKG
PBE
+4.09%-0.36%
+19.10%+13.43%
+2.83%+10.18%
+9.90%+39.59%
+6.98%+44.20%
n/a+21.25%
Flows
EKG
PBE
+$963K+$5M
+$963K+$6M
+$963K+$2M
+$93K-$17M
+$2M-$51M
--$47M
Volatility and drawdown
3M1Y3Y5Y
Volatility
EKG
PBE
+26.19%+19.24%
+23.28%+19.02%
+23.74%+20.29%
n/a+22.50%
Max drawdown
EKG
PBE
-7.45%-4.30%
-22.11%-11.70%
-33.93%-22.21%
n/a-34.74%
Max drawdown duration
EKG
PBE
24d24d
204d166d
491d324d
n/a1540d
Trading data

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EKG
PBE
Last sale
7/31/2026 at 1:30 PM
$19.63
$89.98
Previous close
07/31/2026
$19.55
$89.61
Consolidated volume
07/31/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of July 31, 2026
1-year trailing difference

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EKG
PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 7/31/2026 at 1:30 PM
Live
Closed
EKG
PBE
Last price
$19.63
$89.98
1D performance
+0.41%
+0.41%
AuM$3.91 M$281.95 M
E/R0.65%0.58%
Characteristics
EKG
PBE
Management strategyPassivePassive
ProviderFirst TrustInvesco
BenchmarkNasdaq Lux Health Tech IndexDynamic Biotech & Genome Intellidex Index
N° of holdings3730
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateMarch 22, 2022June 23, 2005
ESGNoNo
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Exposure

Countries

EKG
USA
95.64%
Other
4.36%
PBE
USA
97.25%
Other
2.75%

Sectors

EKG
Healthcare
98.52%
Other
1.48%
PBE
Healthcare
100%
Other
-0%
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Diversification

EKG

Total weight of top 15 holdings out of 15

73.91%
PBE

Total weight of top 15 holdings out of 15

60.29%

Top 15 holdings

Data as of June 30, 2026
EKG
IQVIA Holdings, Inc.
8.32%
Veeva Systems, Inc.
7.41%
DexCom, Inc.
6.87%
Guardant Health, Inc.
6.66%
Intuitive Surgical, Inc.
5.85%
ResMed, Inc.
5.74%
Illumina, Inc.
5.01%
Natera, Inc.
4.87%
Oscar Health, Inc.
4.41%
Tempus AI, Inc.
3.77%
Align Technology, Inc.
3.49%
Hims & Hers Health, Inc.
3.35%
Globus Medical, Inc.
2.91%
QIAGEN NV
2.88%
Insulet Corp.
2.37%
PBE
Vertex Pharmaceuticals, Inc.
5.12%
Biogen, Inc.
5.08%
Amgen, Inc.
4.84%
Royalty Pharma Plc
4.74%
Regeneron Pharmaceuticals, Inc.
4.53%
Alnylam Pharmaceuticals, Inc.
4.48%
Gilead Sciences, Inc.
4.34%
United Therapeutics Corp.
4.26%
Bio-Techne Corp.
3.67%
Veracyte, Inc.
3.39%
CareDx, Inc.
3.31%
Vericel Corp.
3.27%
Repligen Corp.
3.16%
PTC Therapeutics, Inc.
3.09%
Protagonist Therapeutics, Inc.
3.02%
Frequently asked questions about EKG and PBE

How have the EKG and PBE ETFs performed in 2026?

As of July 30, 2026, EKG is up 2.83% year-to-date (YTD), while PBE has returned 10.18%. That puts PBE better performer ahead so far this year.

Which ETF is attracting more investor money: EKG or PBE?

Year-to-date, the EKG ETF saw +$963K in flows, compared to +$2M for PBE.

Which ETF is more volatile: EKG or PBE?

Over the past year, EKG had a volatility of 23.28%, while PBE experienced 19.02%.

Which ETF is bigger: EKG or PBE?

As of July 30, 2026, EKG holds $3.91 M in assets under management (AUM), while PBE manages $281.95 M.

What sectors do the EKG and PBE ETFs invest in?

EKG leans toward sectors like Healthcare. Meanwhile, PBE focuses on Healthcare.

What are the top holdings of the EKG ETF and PBE ETF?

EKG top holdings include IQVIA Holdings, Inc., Veeva Systems, Inc. and DexCom, Inc.. PBE holds in its top three: Vertex Pharmaceuticals, Inc., Biogen, Inc. and Amgen, Inc..

Which ETF is more diversified: EKG or PBE?

EKG holds 37 securities with 73.91% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 60.29%.

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