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EKGvsPBEETF Comparison

ETF 1
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
-0.07%
Full EKG fund page
VS
ETF 2
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
-0.05%
Full PBE fund page

First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) belongs to the Healthcare Technology segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. EKG's top 3 sector exposures are Health Care and Financials. In contrast, PBE's top sector exposures are Health Care  EKG is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.58% for PBE. EKG is down -13.25% year-to-date (YTD) with - in YTD flows. PBE performs better with -7.12% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of EKG and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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EKG vs PBE performance and flow charts

Performance

-6.0-4.0-2.00.02.04.06.0%Feb 12Feb 20Feb 27Mar 6Mar 13

Cumulative Flows

-3.5 M-3 M-2.5 M-2 M-1.5 M-1 M-0.5 M0 MFeb 12Feb 20Feb 27Mar 6Mar 13

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/12/2026
1M3MYTD1Y3Y5Y
Perf.
EKG
PBE
-4.00%-6.52%
-14.51%-5.52%
-13.25%-7.12%
+2.95%+19.22%
+0.49%+26.51%
n/a+1.84%
Flows
EKG
PBE
--$3M
-+$969K
-+$135K
-$25K-$32M
+$1M-$56M
--$39M
Volatility and drawdown
3M1Y3Y5Y
Volatility
EKG
PBE
+20.20%+18.95%
+24.28%+22.28%
+22.65%+20.18%
n/a+22.77%
Max drawdown
EKG
PBE
-18.32%-11.05%
-18.32%-16.18%
-34.97%-22.21%
n/a-34.74%
Max drawdown duration
EKG
PBE
64d65d
64d107d
563d324d
n/a1540d
Trading data

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EKG
PBE
Last sale
3/13/2026 at 1:30 PM
$16.43
$76.18
Previous close
03/12/2026
$16.47
$76.18
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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EKG
PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
EKG
PBE
Last price
$16.43
$76.18
1D performance
-0.25%
+0.00%
AuM$2.47 M$240.98 M
E/R0.65%0.58%
Characteristics
EKG
PBE
Management strategyPassivePassive
ProviderFirst TrustInvesco
BenchmarkNasdaq Lux Health Tech IndexDynamic Biotech & Genome Intellidex Index
N° of holdings3630
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateMarch 22, 2022June 23, 2005
ESGNoNo
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Exposure

Countries

EKG
USA
94.55%
Other
5.45%
PBE
USA
94.25%
Other
5.75%

Sectors

EKG
Health Care
93.91%
Other
6.09%
PBE
Health Care
96.95%
Other
3.05%
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Diversification

EKG

Total weight of top 15 holdings out of 15

78.3%
PBE

Total weight of top 15 holdings out of 15

61.48%

Top 15 holdings

Data as of January 31, 2026
EKG
IQVIA HOLDINGS INC
8.83%
INTUITIVE SURGICAL
7.80%
DEXCOM
7.10%
RESMED
6.89%
EXACT SCIENCES
6.47%
GUARDANT HEALTH INC
5.78%
VEEVA SYSTEMS IN
5.55%
ILLUMINA
5.31%
NATERA
5.03%
ALIGN TECHNOLOGY
4.21%
HOLOGIC
4.09%
GLOBUS MEDICAL
4.05%
INSULET
2.76%
MASIMO
2.35%
HIMS & HERS HEALTH INC
2.08%
PBE
ILLUMINA
5.91%
GILEAD SCIENCES
5.35%
AMGEN-T
5.09%
REGENERON PHARMACEUTICALS
4.87%
UTD THERAPEUT
4.83%
BIOGEN INC
4.76%
INCYTE
4.70%
ALNYLAM PHARMACEUTICALS
4.05%
AMICUS THERAPEUTICS
3.83%
DYNAVAX TECHNOLOGIES
3.60%
NL0015002SN0
3.05%
ACADIA PHARMACEUTICALS
2.98%
MANNKIND
2.89%
BIO-TECHNE CORP
2.83%
EXELIXIS
2.74%
Frequently asked questions about EKG and PBE

How have the EKG and PBE ETFs performed in 2026?

As of March 12, 2026, EKG is down -13.25% year-to-date (YTD), while PBE has lost -7.12%. That puts PBE better performer ahead so far this year.

Which ETF is attracting more investor money: EKG or PBE?

Year-to-date, the EKG ETF saw - in flows, compared to +$135K for PBE.

Which ETF is more volatile: EKG or PBE?

Over the past year, EKG had a volatility of 24.28%, while PBE experienced 22.28%.

Which ETF is bigger: EKG or PBE?

As of March 12, 2026, EKG holds $2.47 M in assets under management (AUM), while PBE manages $240.98 M.

What sectors do the EKG and PBE ETFs invest in?

EKG leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the EKG ETF and PBE ETF?

EKG top holdings include IQVIA HOLDINGS INC, INTUITIVE SURGICAL and DEXCOM. PBE holds in its top three: ILLUMINA, GILEAD SCIENCES and AMGEN-T.

Which ETF is more diversified: EKG or PBE?

EKG holds 36 securities with 78.3% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 61.48%.

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