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EKGvsPBEETF Comparison

ETF 1
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
+0%
VS
ETF 2
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
+0%

First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) belongs to the Healthcare Technology segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. EKG's top 3 sector exposures are Health Care and Financials. In contrast, PBE's top sector exposures are Health Care  EKG is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.58% for PBE. EKG is down -13.71% year-to-date (YTD) with - in YTD flows. PBE performs better with -4.24% YTD performance, and -$4M in YTD flows. Run a side-by-side ETF comparison of EKG and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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EKG vs PBE performance and flow charts

Performance

0246810%Mar 30Apr 7Apr 14Apr 21Apr 28

Cumulative Flows

-0.5 M0 M0.5 M1 M1.5 MMar 30Apr 7Apr 14Apr 21Apr 28

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Historic performance and flows
Data as of 04/28/2026
1M3MYTD1Y3Y5Y
Perf.
EKG
PBE
+4.00%+2.23%
-15.14%-4.67%
-13.71%-4.24%
+4.02%+28.66%
-5.84%+25.55%
n/a+4.21%
Flows
EKG
PBE
-+$18K
--$8M
--$4M
-$25K-$32M
+$1M-$60M
--$44M
Volatility and drawdown
3M1Y3Y5Y
Volatility
EKG
PBE
+26.17%+19.62%
+21.30%+19.88%
+22.96%+20.13%
n/a+22.54%
Max drawdown
EKG
PBE
-18.52%-9.36%
-21.99%-11.70%
-34.97%-22.21%
n/a-34.74%
Max drawdown duration
EKG
PBE
90d80d
111d112d
563d324d
n/a1540d
Trading data

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EKG
PBE
Last sale
4/30/2026 at 7:53 PM
$16.41
$79.49
Previous close
04/29/2026
$15.97
$78.51
Consolidated volume
04/29/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of April 29, 2026
1-year trailing difference

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EKG
PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/30/2026 at 7:53 PM
Live
Closed
EKG
PBE
Last price
$16.41
$79.49
1D performance
+2.76%
+1.25%
AuM$2.46 M$244.25 M
E/R0.65%0.58%
Characteristics
EKG
PBE
Management strategyPassivePassive
ProviderFirst TrustInvesco
BenchmarkNasdaq Lux Health Tech IndexDynamic Biotech & Genome Intellidex Index
N° of holdings3330
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateMarch 22, 2022June 23, 2005
ESGNoNo
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Exposure

Countries

EKG
USA
94.35%
Other
5.65%
PBE
USA
92.18%
Other
7.82%

Sectors

EKG
Health Care
86.01%
Other
13.99%
PBE
Health Care
97.59%
Other
2.41%
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Diversification

EKG

Total weight of top 15 holdings out of 15

74.16%
PBE

Total weight of top 15 holdings out of 15

63.66%

Top 15 holdings

Data as of March 31, 2026
EKG
IQVIA HOLDINGS INC
8.48%
VEEVA SYSTEMS IN
8.34%
INTUITIVE SURGICAL
8.11%
RESMED
7.65%
DEXCOM
7.47%
NATERA
4.30%
GUARDANT HEALTH INC
4.27%
ILLUMINA
4.14%
GLOBUS MEDICAL
4.04%
ALIGN TECHNOLOGY
4.00%
INSULET
3.69%
US88023B1035
3.45%
IRHYTHM TECHNOLOGIES
2.14%
HIMS & HERS HEALTH INC
2.13%
OSCAR HEALTH
1.95%
PBE
UTD THERAPEUT
6.05%
ILLUMINA
5.24%
REGENERON PHARMACEUTICALS
5.23%
ALNYLAM PHARMACEUTICALS
5.22%
BIOGEN INC
5.16%
AMGEN-T
4.99%
GILEAD SCIENCES
4.98%
INCYTE
4.89%
BIOCRYST PHARMACEUTICALS
3.66%
PROTAGONIST THERAPEUTICS INC
3.38%
TG THERAPEUTICS
3.11%
ROYALTY PHARMA
3.05%
NEUROCRINE BIOSCIENCES
2.93%
CATALYST PHARMACEUTICALS INC
2.89%
PTC THERAPEUTI/D
2.86%
Frequently asked questions about EKG and PBE

How have the EKG and PBE ETFs performed in 2026?

As of April 28, 2026, EKG is down -13.71% year-to-date (YTD), while PBE has lost -4.24%. That puts PBE better performer ahead so far this year.

Which ETF is attracting more investor money: EKG or PBE?

Year-to-date, the EKG ETF saw - in flows, compared to -$4M for PBE.

Which ETF is more volatile: EKG or PBE?

Over the past year, EKG had a volatility of 21.3%, while PBE experienced 19.88%.

Which ETF is bigger: EKG or PBE?

As of April 28, 2026, EKG holds $2.46 M in assets under management (AUM), while PBE manages $244.25 M.

What sectors do the EKG and PBE ETFs invest in?

EKG leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the EKG ETF and PBE ETF?

EKG top holdings include IQVIA HOLDINGS INC, VEEVA SYSTEMS IN and INTUITIVE SURGICAL. PBE holds in its top three: UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS.

Which ETF is more diversified: EKG or PBE?

EKG holds 36 securities with 74.16% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 63.66%.

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