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EKGvsIBRNETF Comparison

ETF 1

EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of

Healthcare Technology

-0.08%

Full EKG fund page

VS

ETF 2

IBRN

iShares Neuroscience and Healthcare ETF

This fund is part of

Healthcare Technology

-0.08%

Full IBRN fund page

First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) and iShares Neuroscience and Healthcare ETF (IBRN) belong to the same industry segment: Healthcare Technology. EKG's top 3 sector exposures are Health Care and Financials. In contrast, IBRN's top sector exposures are Health Care and Information Technology. EKG is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.47% for IBRN. EKG is down -11.45% year-to-date (YTD) with - in YTD flows. IBRN performs better with 6.81% YTD performance, and - in YTD flows. Run a side-by-side ETF comparison of EKG and IBRN below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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EKG vs IBRN performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/27/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	EKG IBRN	+6.88%+12.00%	-13.72%+3.53%	-11.45%+6.81%	+6.75%+57.23%	-2.00%+43.91%	n/an/a
Flows	EKG IBRN	--	--	--	-$25K-	+$1M-$1M	--

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	EKG IBRN	+25.78%+30.61%	+21.18%+26.07%	+22.93%+24.67%	n/an/a
Max drawdown	EKG IBRN	-19.27%-8.14%	-21.99%-9.13%	-34.97%-34.98%	n/an/a
Max drawdown duration	EKG IBRN	90d70d	110d32d	563d338d	n/an/a

Trading data

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	EKG	IBRN
Last sale 4/29/2026 at 1:30 PM	$15.97	$34.33
Previous close 04/28/2026	$16.39	$34.47
Consolidated volume 04/28/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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	EKG	IBRN
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/29/2026 at 1:30 PM

Live

Closed

	EKG	IBRN
Last price	$15.97	$34.33
1D performance	-2.54%	-0.42%
AuM	$2.52 M	$5.18 M
E/R	0.65%	0.47%

Characteristics

	EKG	IBRN
Management strategy	Passive	Passive
Provider	First Trust	iShares
Benchmark	Nasdaq Lux Health Tech Index	NYSE FactSet Global Neuro Biopharma and MedTech Index
N° of holdings	33	55
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	March 22, 2022	August 24, 2022
ESG	No	No

More EKG data on Trackinsight

More IBRN data on Trackinsight

Exposure

Countries

EKG

USA

94.35%

Other

5.65%

IBRN

USA

75.38%

Other

24.62%

Sectors

EKG

Health Care

86.01%

Other

13.99%

IBRN

Health Care

75.97%

Other

24.03%

Diversification

EKG

Total weight of top 15 holdings out of 15

74.16%

IBRN

Total weight of top 15 holdings out of 15

58.72%

Top 15 holdings

Data as of March 31, 2026

EKG

IQVIA HOLDINGS INC

8.48%

VEEVA SYSTEMS IN

8.34%

INTUITIVE SURGICAL

8.11%

RESMED

7.65%

DEXCOM

7.47%

NATERA

4.30%

GUARDANT HEALTH INC

4.27%

ILLUMINA

4.14%

GLOBUS MEDICAL

4.04%

ALIGN TECHNOLOGY

4.00%

INSULET

3.69%

US88023B1035

3.45%

IRHYTHM TECHNOLOGIES

2.14%

HIMS & HERS HEALTH INC

2.13%

OSCAR HEALTH

1.95%

IBRN

XENON PHARMACEUTICALS

5.22%

ALKERMES

4.63%

US1523091007

4.18%

SCHOLAR ROCK HOLDING CORP

4.07%

PTC THERAPEUTI/D

4.07%

ARROWHEAD PHARMACEUTICALS INC

3.95%

AXSOME THERA CMN STK

3.93%

US74006W2070

3.89%

NEUROCRINE BIOSCIENCES

3.87%

US04016X1019

3.81%

ACADIA PHARMACEUTICALS

3.77%

BIOGEN INC

3.74%

US2528281080

3.41%

SUPERNUS PHARMACEUTICALS

3.15%

DENALI THERAPEUTICS INC

3.04%

Frequently asked questions about EKG and IBRN

How have the EKG and IBRN ETFs performed in 2026?

As of April 27, 2026, EKG is down -11.45% year-to-date (YTD), while IBRN has returned 6.81%. That puts IBRN better performer ahead so far this year.

Which ETF is attracting more investor money: EKG or IBRN?

Year-to-date, the EKG ETF saw - in flows, compared to - for IBRN.

Which ETF is more volatile: EKG or IBRN?

Over the past year, EKG had a volatility of 21.18%, while IBRN experienced 26.07%.

Which ETF is bigger: EKG or IBRN?

As of April 27, 2026, EKG holds $2.52 M in assets under management (AUM), while IBRN manages $5.18 M.

What sectors do the EKG and IBRN ETFs invest in?

EKG leans toward sectors like Health Care. Meanwhile, IBRN focuses on Health Care.

What are the top holdings of the EKG ETF and IBRN ETF?

EKG top holdings include IQVIA HOLDINGS INC, VEEVA SYSTEMS IN and INTUITIVE SURGICAL. IBRN holds in its top three: XENON PHARMACEUTICALS, ALKERMES and US1523091007.

EKGvsIBRNETF Comparison

First Trust Nasdaq Lux Digital Health Solutions ETF

iShares Neuroscience and Healthcare ETF

EKG vs IBRN performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the EKG and IBRN ETFs performed in 2026?

As of April 27, 2026, EKG is down -11.45% year-to-date (YTD), while IBRN has returned 6.81%. That puts IBRN better performer ahead so far this year.

Which ETF is attracting more investor money: EKG or IBRN?

Year-to-date, the EKG ETF saw - in flows, compared to - for IBRN.

Which ETF is more volatile: EKG or IBRN?

Over the past year, EKG had a volatility of 21.18%, while IBRN experienced 26.07%.

Which ETF is bigger: EKG or IBRN?

As of April 27, 2026, EKG holds $2.52 M in assets under management (AUM), while IBRN manages $5.18 M.

What sectors do the EKG and IBRN ETFs invest in?

EKG leans toward sectors like Health Care. Meanwhile, IBRN focuses on Health Care.

What are the top holdings of the EKG ETF and IBRN ETF?

EKG top holdings include IQVIA HOLDINGS INC, VEEVA SYSTEMS IN and INTUITIVE SURGICAL. IBRN holds in its top three: XENON PHARMACEUTICALS, ALKERMES and US1523091007.

Which ETF is more diversified: EKG or IBRN?

EKG holds 36 securities with 74.16% of its assets in the top 15. IBRN has 75 securities and a top 15 weight of 58.72%.

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