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EKGvsFMEDETF Comparison

ETF 1
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
-0.67%
VS
ETF 2
FMED

Fidelity Disruptive Medicine ETF

This fund is part of
Multiple Trends
-5.28%

First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) belongs to the Healthcare Technology segment. Fidelity Disruptive Medicine ETF (FMED) is part of the Multiple Trends segment. Both ETFs have the same top 1 sector exposures: Healthcare. EKG is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.5% for FMED. EKG is up 31.66% year-to-date (YTD) with +$6M in YTD flows. FMED performs worse with 19.85% YTD performance, and -$17M in YTD flows. Run a side-by-side ETF comparison of EKG and FMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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EKG vs FMED performance and flow charts

Performance

-6.0-4.0-2.00.02.04.06.0%Sep 29Oct 6Oct 13Oct 20Oct 27

Cumulative Flows

01,000,0002,000,0003,000,0004,000,0005,000,000Sep 29Oct 6Oct 13Oct 20Oct 27

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 10/29/2026
1M3MYTD1Y3Y5Y
Perf.
EKG
FMED
+5.76%+0.80%
+28.41%+13.11%
+31.66%+19.85%
+37.20%+23.23%
+107.33%+63.30%
n/an/a
Flows
EKG
FMED
+$5M-
+$5M-
+$6M-$17M
+$6M-$14M
+$7M-$12M
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
EKG
FMED
+25.55%+28.29%
+24.43%+22.86%
+23.86%+19.81%
n/an/a
Max drawdown
EKG
FMED
-5.73%-7.63%
-22.11%-17.78%
-24.32%-19.20%
n/an/a
Max drawdown duration
EKG
FMED
21d69d
208d212d
264d267d
n/an/a
Trading data

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EKG
FMED
Last sale
10/30/2026 at 1:30 PM
$23.93
Previous close
10/29/2026
$25.00
Consolidated volume
10/29/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of October 29, 2026
1-year trailing difference

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FMED
is actively managed and doesn’t replicate an index

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EKG
FMED
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 10/30/2026 at 1:30 PM
Live
Closed
EKG
FMED
Last price
$23.93
–
1D performance
-4.30%
–
AuM$10.01 M$52.73 M
E/R0.65%0.5%
Characteristics
EKG
FMED
Management strategyPassiveActive
ProviderFirst TrustFidelity
BenchmarkNasdaq Lux Health Tech Index-
N° of holdings5171
Asset classEquities-
Trailing 12m distribution yield
Join
Join
Inception dateMarch 22, 2022June 12, 2023
ESGNoNo
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Exposure

Countries

EKG
USA
96.91%
Other
3.09%
FMED
USA
84.97%
Other
15.03%

Sectors

EKG
Healthcare
99.9%
Other
0.1%
FMED
Healthcare
99.49%
Other
0.51%
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Diversification

EKG

Total weight of top 15 holdings out of 15

72.5%
FMED

Total weight of top 15 holdings out of 15

47.18%

Top 15 holdings

Data as of September 30, 2026
EKG
Natera, Inc.
9.62%
Intuitive Surgical, Inc.
8.07%
IQVIA Holdings, Inc.
7.56%
Veeva Systems, Inc.
7.47%
DexCom, Inc.
7.18%
Illumina, Inc.
4.71%
Guardant Health, Inc.
4.16%
ResMed, Inc.
3.48%
Globus Medical, Inc.
3.21%
Tempus AI, Inc.
3.06%
QIAGEN NV
2.99%
Twist Bioscience Corp.
2.85%
Align Technology, Inc.
2.75%
Insulet Corp.
2.73%
Oscar Health, Inc.
2.66%
FMED
10X Genomics, Inc.
5.82%
Natera, Inc.
4.47%
Thermo Fisher Scientific, Inc.
4.19%
Danaher Corp.
3.92%
Illumina, Inc.
3.56%
argenx SE
2.96%
Lifestance Health Group, Inc.
2.87%
Revolution Medicines, Inc.
2.86%
Sartorius Stedim Biotech SA
2.72%
Moderna, Inc.
2.62%
Alnylam Pharmaceuticals, Inc.
2.48%
HeartFlow, Inc.
2.39%
Intuitive Surgical, Inc.
2.20%
Cogent Biosciences, Inc.
2.13%
Caris Life Sciences, Inc.
1.99%
Frequently asked questions about EKG and FMED

How have the EKG and FMED ETFs performed in 2026?

As of October 29, 2026, EKG is up 31.66% year-to-date (YTD), while FMED has returned 19.85%. That puts EKG better performer ahead so far this year.

Which ETF is attracting more investor money: EKG or FMED?

Year-to-date, the EKG ETF saw +$6M in flows, compared to -$17M for FMED.

Which ETF is more volatile: EKG or FMED?

Over the past year, EKG had a volatility of 24.43%, while FMED experienced 22.86%.

Which ETF is bigger: EKG or FMED?

As of October 29, 2026, EKG holds $10.01 M in assets under management (AUM), while FMED manages $52.73 M.

What sectors do the EKG and FMED ETFs invest in?

EKG leans toward sectors like Healthcare. Meanwhile, FMED focuses on Healthcare.

What are the top holdings of the EKG ETF and FMED ETF?

EKG top holdings include Natera, Inc., Intuitive Surgical, Inc. and IQVIA Holdings, Inc.. FMED holds in its top three: 10X Genomics, Inc., Natera, Inc. and Thermo Fisher Scientific, Inc..

Which ETF is more diversified: EKG or FMED?

EKG holds 51 securities with 72.5% of its assets in the top 15. FMED has 71 securities and a top 15 weight of 47.18%.

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