CANCvsWDNAETF Comparison
VS
Tema Oncology ETF (CANC) belongs to the Tomorrow's Treatments segment. WisdomTree BioRevolution Fund (WDNA) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.45% for WDNA. CANC is up 8.22% year-to-date (YTD) with +$52M in YTD flows. WDNA performs worse with 6.38% YTD performance, and -$357K in YTD flows. Run a side-by-side ETF comparison of CANC and WDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
Find out how industry players manage ETF portfolios. Discover our library of Model portfolios
CANC vs WDNA performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | CANC WDNA | -0.48%+0.35% | +3.95%+4.10% | +8.22%+6.38% | +45.49%+41.07% | n/a+6.24% | n/a-27.71% |
| Flows | CANC WDNA | +$5M- | +$11M- | +$52M-$357K | +$69M-$357K | --$524K | -+$2M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | CANC WDNA | +24.37%+24.10% | +22.62%+25.60% | n/a+24.90% | n/a+24.83% |
| Max drawdown | CANC WDNA | -9.20%-9.07% | -9.20%-11.90% | n/a-37.80% | n/a-58.58% |
| Max drawdown duration | CANC WDNA | 54d54d | 54d141d | n/a901d | n/a1744d |
Trading data
CANC | WDNA | |
Last sale 6/12/2026 at 1:30 PM | $37.48 | $18.01 |
| Previous close 06/11/2026 | $37.26 | $18.02 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 13, 2026
1-year trailing difference
Create an account to view replication metrics
Join for free
CANC
is actively managed and doesn’t replicate an indexCANC | WDNA | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Advertisement
Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
CANC | WDNA | |
|---|---|---|
| Last price | $37.48 | $18.01 |
| 1D performance | +0.60% | -0.08% |
| AuM | $178.42 M | $2.34 M |
| E/R | 0.99% | 0.45% |
Characteristics
CANC | WDNA | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Tema | WisdomTree |
| Benchmark | - | WisdomTree BioRevolution Index |
| N° of holdings | 42 | 72 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | August 15, 2023 | June 3, 2021 |
| ESG | No | No |
Advertisement
Exposure
Countries
CANC
USA
87.11%
Other
12.89%
WDNA
USA
82.87%
Other
17.13%
Sectors
CANC
Health Care
76.64%
Other
23.36%
WDNA
Health Care
79.21%
Other
20.79%
Advertisement
Diversification
CANC
Total weight of top 15 holdings out of 15
54.47%
WDNA
Total weight of top 15 holdings out of 15
39.77%
Top 15 holdings
Data as of April 30, 2026
CANC
REVOLUTION MEDICINES INC
6.51%
IMMUNOME
4.24%
US7711951043
4.15%
COGENT BIOSCIENCES
4.07%
NOVARTIS
4.00%
LILLY
3.81%
ASTRAZENECA
3.62%
BRISTOL-MYERS SQUIBB
3.36%
MERCK & CO INC
3.34%
CELCUITY INC
3.31%
NUVALENT
3.20%
BRIDGEBIO PHARMA
2.84%
US3723032062
2.82%
LEGEND BIOTECH
2.63%
US98887Q1040
2.57%
WDNA
TWIST BIOSCIENCE CORP
3.90%
LILLY
3.44%
MODERNA INC
3.21%
JOHNSON&JOHNSON
3.16%
UTD THERAPEUT
3.07%
IMMUNOME
2.90%
DARLING INGREDIENTS INC
2.65%
STOKE THERAPEUTICS INC
2.46%
US88023B1035
2.34%
CORTEVA INC
2.22%
BEAM THERAPEUTICS
2.12%
ASTRAZENECA
2.12%
CH1300646267
2.12%
IONIS PHARMACEUTICALS INC
2.08%
NATERA
1.98%
Frequently asked questions about CANC and WDNA
How have the CANC and WDNA ETFs performed in 2026?
As of June 12, 2026, CANC is up 8.22% year-to-date (YTD), while WDNA has returned 6.38%. That puts CANC better performer ahead so far this year.
Which ETF is attracting more investor money: CANC or WDNA?
Year-to-date, the CANC ETF saw +$52M in flows, compared to -$357K for WDNA.
Which ETF is more volatile: CANC or WDNA?
Over the past year, CANC had a volatility of 22.62%, while WDNA experienced 25.6%.
Which ETF is bigger: CANC or WDNA?
As of June 12, 2026, CANC holds $178.42 M in assets under management (AUM), while WDNA manages $2.34 M.
What sectors do the CANC and WDNA ETFs invest in?
CANC leans toward sectors like Health Care. Meanwhile, WDNA focuses on Health Care.
What are the top holdings of the CANC ETF and WDNA ETF?
CANC top holdings include REVOLUTION MEDICINES INC, IMMUNOME and US7711951043. WDNA holds in its top three: TWIST BIOSCIENCE CORP, LILLY and MODERNA INC.
Which ETF is more diversified: CANC or WDNA?
CANC holds 53 securities with 54.47% of its assets in the top 15. WDNA has 80 securities and a top 15 weight of 39.77%.
Advertisement
Advertisement
