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CANCvsWDNAETF Comparison

ETF 1
CANC

Tema Oncology ETF

This fund is part of
Tomorrow's Treatments
-0.51%
Full CANC fund page
VS
ETF 2
WDNA

WisdomTree BioRevolution Fund

This fund is part of
BioTech & Genomics
-0.05%
Full WDNA fund page

Tema Oncology ETF (CANC) belongs to the Tomorrow's Treatments segment. WisdomTree BioRevolution Fund (WDNA) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.45% for WDNA. CANC is up 3.55% year-to-date (YTD) with +$43M in YTD flows. WDNA performs worse with 1.25% YTD performance, and -$357K in YTD flows. Run a side-by-side ETF comparison of CANC and WDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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CANC vs WDNA performance and flow charts

Performance

-4.0-2.00.02.04.0%Feb 13Feb 23Mar 2Mar 9

Cumulative Flows

02,000,0004,000,0006,000,0008,000,00010,000,00012,000,00014,000,000Feb 13Feb 23Mar 2Mar 9

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/13/2026
1M3MYTD1Y3Y5Y
Perf.
CANC
WDNA
-1.54%-3.53%
+2.94%+1.22%
+3.55%+1.25%
+44.18%+34.84%
n/a+8.51%
n/an/a
Flows
CANC
WDNA
+$14M-
+$51M-$357K
+$43M-$357K
+$65M-$357K
--$524K
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
CANC
WDNA
+23.29%+23.55%
+25.12%+28.66%
n/a+24.59%
n/an/a
Max drawdown
CANC
WDNA
-5.18%-9.63%
-17.26%-17.47%
n/a-37.80%
n/an/a
Max drawdown duration
CANC
WDNA
17d50d
80d106d
n/a901d
n/an/a
Trading data

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CANC
WDNA
Last sale
3/13/2026 at 1:30 PM
$35.99
$17.08
Previous close
03/12/2026
$36.33
$17.25
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 14, 2026
1-year trailing difference

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CANC
is actively managed and doesn’t replicate an index

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CANC
WDNA
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
CANC
WDNA
Last price
$35.99
$17.08
1D performance
-0.95%
-1.00%
AuM$162.12 M$2.23 M
E/R0.99%0.45%
Characteristics
CANC
WDNA
Management strategyActivePassive
ProviderTemaWisdomTree
Benchmark-WisdomTree BioRevolution Index
N° of holdings4675
Asset class-Equities
Trailing 12m distribution yield
Join
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Inception dateAugust 15, 2023June 3, 2021
ESGNoNo
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Exposure

Countries

CANC
USA
88.08%
Other
11.92%
WDNA
USA
82.35%
Other
17.65%

Sectors

CANC
Health Care
80.79%
Other
19.21%
WDNA
Health Care
78.82%
Other
21.18%

Diversification

CANC

Total weight of top 15 holdings out of 15

56.2%
WDNA

Total weight of top 15 holdings out of 15

37.91%

Top 15 holdings

Data as of January 31, 2026
CANC
REVOLUTION MEDICINES INC
6.31%
BRIDGEBIO PHARMA
4.61%
NOVARTIS
4.56%
ASTRAZENECA
4.33%
US7711951043
4.14%
LILLY
3.94%
BRISTOL-MYERS SQUIBB
3.89%
US3723032062
3.68%
MERCK & CO INC
3.49%
COGENT BIOSCIENCES
3.42%
NUVALENT
3.25%
IMMUNOME
2.96%
CELCUITY INC
2.67%
AMGEN-T
2.51%
JOHNSON&JOHNSON
2.44%
WDNA
US86366E1064
3.83%
MODERNA INC
3.80%
NATERA
2.81%
LILLY
2.78%
JOHNSON&JOHNSON
2.75%
BIONTECH SE ADR
2.56%
DK0062498333
2.41%
PFIZER
2.34%
STOKE THERAPEUTICS INC
2.15%
AMGEN-T
2.15%
IONIS PHARMACEUTICALS INC
2.12%
BEAM THERAPEUTICS
2.08%
UTD THERAPEUT
2.08%
AMICUS THERAPEUTICS
2.05%
US0463531089
2.03%
Frequently asked questions about CANC and WDNA

How have the CANC and WDNA ETFs performed in 2026?

As of March 13, 2026, CANC is up 3.55% year-to-date (YTD), while WDNA has returned 1.25%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: CANC or WDNA?

Year-to-date, the CANC ETF saw +$43M in flows, compared to -$357K for WDNA.

Which ETF is more volatile: CANC or WDNA?

Over the past year, CANC had a volatility of 25.12%, while WDNA experienced 28.66%.

Which ETF is bigger: CANC or WDNA?

As of March 13, 2026, CANC holds $162.12 M in assets under management (AUM), while WDNA manages $2.23 M.

What sectors do the CANC and WDNA ETFs invest in?

CANC leans toward sectors like Health Care. Meanwhile, WDNA focuses on Health Care.

What are the top holdings of the CANC ETF and WDNA ETF?

CANC top holdings include REVOLUTION MEDICINES INC, BRIDGEBIO PHARMA and NOVARTIS. WDNA holds in its top three: US86366E1064, MODERNA INC and NATERA.

Which ETF is more diversified: CANC or WDNA?

CANC holds 56 securities with 56.2% of its assets in the top 15. WDNA has 85 securities and a top 15 weight of 37.91%.

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