CANCvsMEDXETF Comparison
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Tema Oncology ETF (CANC) and Horizon Kinetics Medical ETF (MEDX) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.85% for MEDX. CANC is up 8.22% year-to-date (YTD) with +$52M in YTD flows. MEDX performs worse with 3.66% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of CANC and MEDX below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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CANC vs MEDX performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | CANC MEDX | -0.48%+4.56% | +3.95%+3.12% | +8.22%+3.66% | +45.49%+27.83% | n/a+21.11% | n/an/a |
| Flows | CANC MEDX | +$5M-$853K | +$11M-$2M | +$52M-$2M | +$69M-$2M | --$4M | -- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | CANC MEDX | +24.37%+19.25% | +22.62%+17.79% | n/a+16.85% | n/an/a |
| Max drawdown | CANC MEDX | -9.20%-5.88% | -9.20%-10.65% | n/a-23.05% | n/an/a |
| Max drawdown duration | CANC MEDX | 54d55d | 54d103d | n/a393d | n/an/a |
Trading data
CANC | MEDX | |
Last sale 6/12/2026 at 1:30 PM | $37.48 | $34.49 |
| Previous close 06/11/2026 | $37.26 | $34.74 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
CANC | MEDX | |
|---|---|---|
| Last price | $37.48 | $34.49 |
| 1D performance | +0.60% | -0.71% |
| AuM | $178.42 M | $17.92 M |
| E/R | 0.99% | 0.85% |
Characteristics
CANC | MEDX | |
|---|---|---|
| Management strategy | Active | Active |
| Provider | Tema | Horizon Kinetics LLC |
| Benchmark | - | - |
| N° of holdings | 42 | 25 |
| Asset class | - | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | August 15, 2023 | January 27, 2023 |
| ESG | No | No |
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Exposure
Countries
CANC
USA
87.11%
Other
12.89%
MEDX
USA
78.22%
Other
21.78%
Sectors
CANC
Health Care
76.64%
Other
23.36%
MEDX
Health Care
78.89%
Other
21.11%
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Diversification
CANC
Total weight of top 15 holdings out of 15
54.47%
MEDX
Total weight of top 15 holdings out of 15
80.85%
Top 15 holdings
Data as of April 30, 2026
CANC
REVOLUTION MEDICINES INC
6.51%
IMMUNOME
4.24%
US7711951043
4.15%
COGENT BIOSCIENCES
4.07%
NOVARTIS
4.00%
LILLY
3.81%
ASTRAZENECA
3.62%
BRISTOL-MYERS SQUIBB
3.36%
MERCK & CO INC
3.34%
CELCUITY INC
3.31%
NUVALENT
3.20%
BRIDGEBIO PHARMA
2.84%
US3723032062
2.82%
LEGEND BIOTECH
2.63%
US98887Q1040
2.57%
MEDX
LILLY
15.38%
ABBVIE
7.99%
US66987V1098
7.30%
JOHNSON&JOHNSON
5.71%
ASTRAZENECA
5.67%
BRISTOL-MYERS SQUIBB
5.10%
IONIS PHARMACEUTICALS INC
4.75%
AMGEN-T
4.23%
ALKERMES
4.10%
ALNYLAM PHARMACEUTICALS
4.03%
MERCK & CO INC
3.90%
PFIZER
3.66%
US37733W2044
3.22%
BIOGEN INC
2.97%
CRISPR THERAPEUTICS
2.84%
Frequently asked questions about CANC and MEDX
How have the CANC and MEDX ETFs performed in 2026?
As of June 12, 2026, CANC is up 8.22% year-to-date (YTD), while MEDX has returned 3.66%. That puts CANC better performer ahead so far this year.
Which ETF is attracting more investor money: CANC or MEDX?
Year-to-date, the CANC ETF saw +$52M in flows, compared to -$2M for MEDX.
Which ETF is more volatile: CANC or MEDX?
Over the past year, CANC had a volatility of 22.62%, while MEDX experienced 17.79%.
Which ETF is bigger: CANC or MEDX?
As of June 12, 2026, CANC holds $178.42 M in assets under management (AUM), while MEDX manages $17.92 M.
What sectors do the CANC and MEDX ETFs invest in?
CANC leans toward sectors like Health Care. Meanwhile, MEDX focuses on Health Care.
What are the top holdings of the CANC ETF and MEDX ETF?
CANC top holdings include REVOLUTION MEDICINES INC, IMMUNOME and US7711951043. MEDX holds in its top three: LILLY, ABBVIE and US66987V1098.
Which ETF is more diversified: CANC or MEDX?
CANC holds 53 securities with 54.47% of its assets in the top 15. MEDX has 29 securities and a top 15 weight of 80.85%.
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