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CANCvsMEDXETF Comparison

ETF 1
CANC

Tema Oncology ETF

This fund is part of
Tomorrow's Treatments
-0.51%
Full CANC fund page
VS
ETF 2
MEDX

Horizon Kinetics Medical ETF

This fund is part of
Tomorrow's Treatments
-0.51%
Full MEDX fund page

Tema Oncology ETF (CANC) and Horizon Kinetics Medical ETF (MEDX) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.85% for MEDX. CANC is up 3.55% year-to-date (YTD) with +$43M in YTD flows. MEDX performs worse with -0.17% YTD performance, and - in YTD flows. Run a side-by-side ETF comparison of CANC and MEDX below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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CANC vs MEDX performance and flow charts

Performance

-4.0-2.00.02.04.0%Feb 13Feb 23Mar 2Mar 9

Cumulative Flows

02,000,0004,000,0006,000,0008,000,00010,000,00012,000,00014,000,000Feb 13Feb 23Mar 2Mar 9

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/13/2026
1M3MYTD1Y3Y5Y
Perf.
CANC
MEDX
-1.54%-4.47%
+2.94%-0.59%
+3.55%-0.17%
+44.18%+20.00%
n/a+25.75%
n/an/a
Flows
CANC
MEDX
+$14M-
+$51M-
+$43M-
+$65M-$787K
--$2M
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
CANC
MEDX
+23.29%+18.58%
+25.12%+20.53%
n/a+16.48%
n/an/a
Max drawdown
CANC
MEDX
-5.18%-6.45%
-17.26%-15.58%
n/a-23.05%
n/an/a
Max drawdown duration
CANC
MEDX
17d12d
80d148d
n/a393d
n/an/a
Trading data

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CANC
MEDX
Last sale
3/13/2026 at 1:30 PM
$35.99
$33.20
Previous close
03/12/2026
$36.33
$33.42
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
CANC
MEDX
Last price
$35.99
$33.20
1D performance
-0.95%
-0.65%
AuM$162.12 M$18.91 M
E/R0.99%0.85%
Characteristics
CANC
MEDX
Management strategyActiveActive
ProviderTemaHorizon Kinetics LLC
Benchmark--
N° of holdings4624
Asset class--
Trailing 12m distribution yield
Join
Join
Inception dateAugust 15, 2023January 27, 2023
ESGNoNo
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Exposure

Countries

CANC
USA
88.08%
Other
11.92%
MEDX
USA
84.84%
Other
15.16%

Sectors

CANC
Health Care
80.79%
Other
19.21%
MEDX
Health Care
74.67%
Other
25.33%
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Diversification

CANC

Total weight of top 15 holdings out of 15

56.2%
MEDX

Total weight of top 15 holdings out of 15

81.25%

Top 15 holdings

Data as of January 31, 2026
CANC
REVOLUTION MEDICINES INC
6.31%
BRIDGEBIO PHARMA
4.61%
NOVARTIS
4.56%
ASTRAZENECA
4.33%
US7711951043
4.14%
LILLY
3.94%
BRISTOL-MYERS SQUIBB
3.89%
US3723032062
3.68%
MERCK & CO INC
3.49%
COGENT BIOSCIENCES
3.42%
NUVALENT
3.25%
IMMUNOME
2.96%
CELCUITY INC
2.67%
AMGEN-T
2.51%
JOHNSON&JOHNSON
2.44%
MEDX
LILLY
17.29%
ABBVIE
8.44%
US66987V1098
7.14%
JOHNSON&JOHNSON
5.50%
US0463531089
5.38%
IONIS PHARMACEUTICALS INC
5.14%
BRISTOL-MYERS SQUIBB
4.60%
ALNYLAM PHARMACEUTICALS
4.36%
AMGEN-T
4.06%
ALKERMES
3.93%
MERCK & CO INC
3.61%
PFIZER
3.37%
CRISPR THERAPEUTICS
2.85%
US37733W2044
2.84%
BIOGEN INC
2.74%
Frequently asked questions about CANC and MEDX

How have the CANC and MEDX ETFs performed in 2026?

As of March 13, 2026, CANC is up 3.55% year-to-date (YTD), while MEDX has lost -0.17%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: CANC or MEDX?

Year-to-date, the CANC ETF saw +$43M in flows, compared to - for MEDX.

Which ETF is more volatile: CANC or MEDX?

Over the past year, CANC had a volatility of 25.12%, while MEDX experienced 20.53%.

Which ETF is bigger: CANC or MEDX?

As of March 13, 2026, CANC holds $162.12 M in assets under management (AUM), while MEDX manages $18.91 M.

What sectors do the CANC and MEDX ETFs invest in?

CANC leans toward sectors like Health Care. Meanwhile, MEDX focuses on Health Care.

What are the top holdings of the CANC ETF and MEDX ETF?

CANC top holdings include REVOLUTION MEDICINES INC, BRIDGEBIO PHARMA and NOVARTIS. MEDX holds in its top three: LILLY, ABBVIE and US66987V1098.

Which ETF is more diversified: CANC or MEDX?

CANC holds 56 securities with 56.2% of its assets in the top 15. MEDX has 29 securities and a top 15 weight of 81.25%.

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