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CANCvsIBBQETF Comparison

ETF 1

CANC

Tema Oncology ETF

This fund is part of

Tomorrow's Treatments

-0.42%

Full CANC fund page

VS

ETF 2

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

-0.5%

Full IBBQ fund page

Tema Oncology ETF (CANC) belongs to the Tomorrow's Treatments segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.19% for IBBQ. CANC is up 7.01% year-to-date (YTD) with +$50M in YTD flows. IBBQ performs worse with 1.73% YTD performance, and +$290K in YTD flows. Run a side-by-side ETF comparison of CANC and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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CANC vs IBBQ performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 05/01/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	CANC IBBQ	+0.28%-1.29%	+1.89%-1.87%	+7.01%+1.73%	+50.04%+38.66%	n/a+40.14%	n/an/a
Flows	CANC IBBQ	+$4M-$8M	+$26M-$7M	+$50M+$290K	+$70M+$14M	-+$34M	--

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	CANC IBBQ	+23.73%+22.39%	+23.55%+21.06%	n/a+19.64%	n/an/a
Max drawdown	CANC IBBQ	-7.99%-8.38%	-10.53%-8.39%	n/a-23.78%	n/an/a
Max drawdown duration	CANC IBBQ	43d48d	32d33d	n/a375d	n/an/a

Trading data

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	CANC	IBBQ
Last sale 5/1/2026 at 1:30 PM	$37.15	$28.84
Previous close 04/29/2026	$37.51	$29.16
Consolidated volume 04/29/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of April 30, 2026

1-year trailing difference

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CANC

is actively managed and doesn’t replicate an index

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	CANC	IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 5/1/2026 at 1:30 PM

Live

Closed

	CANC	IBBQ
Last price	$37.15	$28.84
1D performance	-0.97%	-1.10%
AuM	$173.84 M	$65.16 M
E/R	0.99%	0.19%

Characteristics

	CANC	IBBQ
Management strategy	Active	Passive
Provider	Tema	Invesco
Benchmark	-	NASDAQ Biotechnology Index
N° of holdings	44	192
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	August 15, 2023	June 9, 2021
ESG	No	No

More CANC data on Trackinsight

More IBBQ data on Trackinsight

Exposure

Countries

CANC

USA

85.51%

Other

14.49%

IBBQ

USA

92.77%

Other

7.23%

Sectors

CANC

Health Care

78.17%

Other

21.83%

IBBQ

Health Care

85.9%

Other

14.1%

Diversification

CANC

Total weight of top 15 holdings out of 15

56.1%

IBBQ

Total weight of top 15 holdings out of 15

51.37%

Top 15 holdings

Data as of March 31, 2026

CANC

REVOLUTION MEDICINES INC

4.95%

ASTRAZENECA

4.60%

NOVARTIS

4.45%

US7711951043

4.26%

LILLY

4.20%

BRIDGEBIO PHARMA

3.94%

COGENT BIOSCIENCES

3.88%

BRISTOL-MYERS SQUIBB

3.74%

MERCK & CO INC

3.62%

IMMUNOME

3.30%

JOHNSON&JOHNSON

3.23%

NUVALENT

3.20%

CELCUITY INC

3.07%

US3723032062

2.95%

ABBVIE

2.71%

IBBQ

GILEAD SCIENCES

7.85%

AMGEN-T

7.82%

VERTEX PHARMACEUTICALS

7.59%

REGENERON PHARMACEUTICALS

6.48%

ALNYLAM PHARMACEUTICALS

3.56%

INSMED

2.65%

BIOGEN INC

2.28%

UTD THERAPEUT

1.94%

ROYALTY PHARMA

1.68%

US04016X1019

1.66%

MODERNA INC

1.66%

ROIVANT SCIENCES LTD

1.61%

REVOLUTION MEDICINES INC

1.55%

ILLUMINA

1.52%

INCYTE

1.52%

Frequently asked questions about CANC and IBBQ

How have the CANC and IBBQ ETFs performed in 2026?

As of May 1, 2026, CANC is up 7.01% year-to-date (YTD), while IBBQ has returned 1.73%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: CANC or IBBQ?

Year-to-date, the CANC ETF saw +$50M in flows, compared to +$290K for IBBQ.

Which ETF is more volatile: CANC or IBBQ?

Over the past year, CANC had a volatility of 23.55%, while IBBQ experienced 21.06%.

Which ETF is bigger: CANC or IBBQ?

As of May 1, 2026, CANC holds $173.84 M in assets under management (AUM), while IBBQ manages $65.16 M.

What sectors do the CANC and IBBQ ETFs invest in?

CANC leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the CANC ETF and IBBQ ETF?

CANC top holdings include REVOLUTION MEDICINES INC, ASTRAZENECA and NOVARTIS. IBBQ holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.

CANCvsIBBQETF Comparison

Tema Oncology ETF

Invesco Nasdaq Biotechnology ETF

CANC vs IBBQ performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the CANC and IBBQ ETFs performed in 2026?

As of May 1, 2026, CANC is up 7.01% year-to-date (YTD), while IBBQ has returned 1.73%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: CANC or IBBQ?

Year-to-date, the CANC ETF saw +$50M in flows, compared to +$290K for IBBQ.

Which ETF is more volatile: CANC or IBBQ?

Over the past year, CANC had a volatility of 23.55%, while IBBQ experienced 21.06%.

Which ETF is bigger: CANC or IBBQ?

As of May 1, 2026, CANC holds $173.84 M in assets under management (AUM), while IBBQ manages $65.16 M.

What sectors do the CANC and IBBQ ETFs invest in?

CANC leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the CANC ETF and IBBQ ETF?

CANC top holdings include REVOLUTION MEDICINES INC, ASTRAZENECA and NOVARTIS. IBBQ holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.

Which ETF is more diversified: CANC or IBBQ?

CANC holds 54 securities with 56.1% of its assets in the top 15. IBBQ has 256 securities and a top 15 weight of 51.37%.

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