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CANCvsGNOMETF Comparison

ETF 1
CANC

Tema Oncology ETF

This fund is part of
Tomorrow's Treatments
-0.51%
Full CANC fund page
VS
ETF 2
GNOM

Global X Genomics & Biotechnology ETF - USD

This fund is part of
BioTech & Genomics
-0.05%
Full GNOM fund page

Tema Oncology ETF (CANC) belongs to the Tomorrow's Treatments segment. Global X Genomics & Biotechnology ETF - USD (GNOM) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.5% for GNOM. CANC is up 3.55% year-to-date (YTD) with +$43M in YTD flows. GNOM performs worse with -4.83% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of CANC and GNOM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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CANC vs GNOM performance and flow charts

Performance

-6.0-4.0-2.00.02.04.0%Feb 13Feb 23Mar 2Mar 9

Cumulative Flows

02,000,0004,000,0006,000,0008,000,00010,000,00012,000,00014,000,000Feb 13Feb 23Mar 2Mar 9

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/13/2026
1M3MYTD1Y3Y5Y
Perf.
CANC
GNOM
-1.54%-5.57%
+2.94%-6.28%
+3.55%-4.83%
+44.18%+25.75%
n/a-9.66%
n/a-54.21%
Flows
CANC
GNOM
+$14M-
+$51M-$4M
+$43M-$2M
+$65M-$19M
--$115M
-+$8M
Volatility and drawdown
3M1Y3Y5Y
Volatility
CANC
GNOM
+23.29%+24.33%
+25.12%+30.10%
n/a+28.55%
n/a+33.48%
Max drawdown
CANC
GNOM
-5.18%-14.34%
-17.26%-22.14%
n/a-46.50%
n/a-72.17%
Max drawdown duration
CANC
GNOM
17d50d
80d113d
n/a1033d
n/a1716d
Trading data

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CANC
GNOM
Last sale
3/13/2026 at 1:30 PM
$35.99
$43.24
Previous close
03/12/2026
$36.33
$43.61
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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CANC
is actively managed and doesn’t replicate an index

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CANC
GNOM
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
CANC
GNOM
Last price
$35.99
$43.24
1D performance
-0.95%
-0.84%
AuM$162.12 M$47.44 M
E/R0.99%0.5%
Characteristics
CANC
GNOM
Management strategyActivePassive
ProviderTemaGlobal X
Benchmark-Solactive Genomics Index
N° of holdings4646
Asset class-Equities
Trailing 12m distribution yield
Join
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Inception dateAugust 15, 2023April 5, 2019
ESGNoNo
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Exposure

Countries

CANC
USA
88.08%
Other
11.92%
GNOM
USA
87.04%
Other
12.96%

Sectors

CANC
Health Care
80.79%
Other
19.21%
GNOM
Health Care
87.95%
Other
12.05%
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Diversification

CANC

Total weight of top 15 holdings out of 15

56.2%
GNOM

Total weight of top 15 holdings out of 15

63.95%

Top 15 holdings

Data as of January 31, 2026
CANC
REVOLUTION MEDICINES INC
6.31%
BRIDGEBIO PHARMA
4.61%
NOVARTIS
4.56%
ASTRAZENECA
4.33%
US7711951043
4.14%
LILLY
3.94%
BRISTOL-MYERS SQUIBB
3.89%
US3723032062
3.68%
MERCK & CO INC
3.49%
COGENT BIOSCIENCES
3.42%
NUVALENT
3.25%
IMMUNOME
2.96%
CELCUITY INC
2.67%
AMGEN-T
2.51%
JOHNSON&JOHNSON
2.44%
GNOM
MODERNA INC
6.79%
ARROWHEAD PHARMACEUTICALS INC
6.14%
US74006W2070
5.75%
ILLUMINA
5.64%
GUARDANT HEALTH INC
5.47%
NATERA
4.30%
VERTEX PHARMACEUTICALS
4.08%
BIONTECH SE ADR
4.04%
BIOMARIN PHARMACEUTICAL
3.93%
AVIDITY BIOSCIENCES
3.73%
BIO-TECHNE CORP
3.69%
CRISPR THERAPEUTICS
3.05%
ALNYLAM PHARMACEUTICALS
2.58%
VERACYTE INC/D
2.50%
BRISTOL-MYERS SQUIBB
2.28%
Frequently asked questions about CANC and GNOM

How have the CANC and GNOM ETFs performed in 2026?

As of March 13, 2026, CANC is up 3.55% year-to-date (YTD), while GNOM has lost -4.83%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: CANC or GNOM?

Year-to-date, the CANC ETF saw +$43M in flows, compared to -$2M for GNOM.

Which ETF is more volatile: CANC or GNOM?

Over the past year, CANC had a volatility of 25.12%, while GNOM experienced 30.1%.

Which ETF is bigger: CANC or GNOM?

As of March 13, 2026, CANC holds $162.12 M in assets under management (AUM), while GNOM manages $47.44 M.

What sectors do the CANC and GNOM ETFs invest in?

CANC leans toward sectors like Health Care. Meanwhile, GNOM focuses on Health Care.

What are the top holdings of the CANC ETF and GNOM ETF?

CANC top holdings include REVOLUTION MEDICINES INC, BRIDGEBIO PHARMA and NOVARTIS. GNOM holds in its top three: MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070.

Which ETF is more diversified: CANC or GNOM?

CANC holds 56 securities with 56.2% of its assets in the top 15. GNOM has 48 securities and a top 15 weight of 63.95%.

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