CANCvsFMEDETF Comparison
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Tema Oncology ETF (CANC) belongs to the Tomorrow's Treatments segment. Fidelity Disruptive Medicine ETF (FMED) is part of the Multiple Trends segment. Both ETFs have the same top 3 sector exposures: and Healthcare. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.5% for FMED. CANC is up 18.41% year-to-date (YTD) with +$52M in YTD flows. FMED performs worse with 4.78% YTD performance, and -$17M in YTD flows. Run a side-by-side ETF comparison of CANC and FMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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CANC vs FMED performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | CANC FMED | -0.28%-0.72% | +8.61%+13.05% | +18.41%+4.78% | +53.77%+18.10% | n/a+13.64% | n/an/a |
| Flows | CANC FMED | -$2M- | +$3M-$17M | +$52M-$17M | +$76M-$14M | --$6M | -- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | CANC FMED | +23.01%+22.48% | +22.71%+19.53% | n/a+18.59% | n/an/a |
| Max drawdown | CANC FMED | -5.93%-5.92% | -9.20%-17.78% | n/a-21.42% | n/an/a |
| Max drawdown duration | CANC FMED | 47d18d | 67d212d | n/a211d | n/an/a |
Trading data
CANC | FMED | |
Last sale 7/28/2026 at 1:30 PM | $41.18 | |
| Previous close 07/27/2026 | $41.10 | |
| Consolidated volume 07/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 7/28/2026 at 1:30 PM
Live
Closed
CANC | FMED | |
|---|---|---|
| Last price | $41.18 | – |
| 1D performance | +0.20% | – |
| AuM | $195.62 M | $46.10 M |
| E/R | 0.99% | 0.5% |
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Exposure
Countries
CANC
USA
80.59%
Switzerland
9.85%
Other
9.56%
FMED
USA
83.89%
Other
16.11%
Sectors
CANC
Healthcare
99.28%
Other
0.72%
FMED
Healthcare
100%
Other
-0%
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Diversification
CANC
Total weight of top 15 holdings out of 15
55.76%
FMED
Total weight of top 15 holdings out of 15
41.87%
Top 15 holdings
Data as of June 30, 2026
CANC
Revolution Medicines, Inc.
6.32%
Eli Lilly & Co.
5.24%
Cogent Biosciences, Inc.
4.94%
Novartis AG
4.19%
Roche Holding AG
3.93%
Legend Biotech Corp.
3.70%
Merck & Co., Inc.
3.66%
Bristol Myers Squibb Co.
3.33%
AstraZeneca PLC
3.15%
Johnson & Johnson
3.09%
AbbVie, Inc.
3.08%
Immunome, Inc.
2.87%
Exelixis, Inc.
2.85%
Nuvalent, Inc.
2.73%
IDEAYA Biosciences, Inc.
2.68%
FMED
Lifestance Health Group, Inc.
5.11%
10X Genomics, Inc.
3.56%
Danaher Corp.
3.29%
UCB SA
3.09%
Cogent Biosciences, Inc.
2.79%
Bio-Techne Corp.
2.76%
Moderna, Inc.
2.69%
Intuitive Surgical, Inc.
2.49%
argenx SE
2.43%
Alnylam Pharmaceuticals, Inc.
2.41%
Kymera Therapeutics, Inc.
2.36%
UnitedHealth Group, Inc.
2.27%
Thermo Fisher Scientific, Inc.
2.24%
Ascendis Pharma A/S
2.21%
Legend Biotech Corp.
2.17%
Frequently asked questions about CANC and FMED
How have the CANC and FMED ETFs performed in 2026?
As of July 27, 2026, CANC is up 18.41% year-to-date (YTD), while FMED has returned 4.78%. That puts CANC better performer ahead so far this year.
Which ETF is attracting more investor money: CANC or FMED?
Year-to-date, the CANC ETF saw +$52M in flows, compared to -$17M for FMED.
Which ETF is more volatile: CANC or FMED?
Over the past year, CANC had a volatility of 22.71%, while FMED experienced 19.53%.
Which ETF is bigger: CANC or FMED?
As of July 27, 2026, CANC holds $195.62 M in assets under management (AUM), while FMED manages $46.10 M.
What sectors do the CANC and FMED ETFs invest in?
CANC leans toward sectors like Healthcare. Meanwhile, FMED focuses on Healthcare.
What are the top holdings of the CANC ETF and FMED ETF?
CANC top holdings include Revolution Medicines, Inc., Eli Lilly & Co. and Cogent Biosciences, Inc.. FMED holds in its top three: Lifestance Health Group, Inc., 10X Genomics, Inc. and Danaher Corp..
Which ETF is more diversified: CANC or FMED?
CANC holds 56 securities with 55.76% of its assets in the top 15. FMED has 69 securities and a top 15 weight of 41.87%.
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