CANCvsFBTETF Comparison
VS
Tema Oncology ETF (CANC) belongs to the Tomorrow's Treatments segment. First Trust NYSE Arca Biotechnology Index Fund ETF (FBT) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Healthcare. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.54% for FBT. CANC is up 18.41% year-to-date (YTD) with +$52M in YTD flows. FBT performs better with 20.24% YTD performance, and +$1.03B in YTD flows. Run a side-by-side ETF comparison of CANC and FBT below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
Find out how industry players manage ETF portfolios. Discover our library of Model portfolios
CANC vs FBT performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | CANC FBT | -0.28%+4.30% | +8.61%+21.28% | +18.41%+20.24% | +53.77%+49.10% | n/a+60.11% | n/a+49.90% |
| Flows | CANC FBT | -$2M-$98M | +$3M-$45M | +$52M+$1.03B | +$76M+$1.08B | -+$634M | -+$293M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | CANC FBT | +23.01%+21.65% | +22.71%+21.18% | n/a+20.61% | n/a+22.14% |
| Max drawdown | CANC FBT | -5.93%-4.37% | -9.20%-14.27% | n/a-19.92% | n/a-29.91% |
| Max drawdown duration | CANC FBT | 47d17d | 67d126d | n/a237d | n/a1159d |
Trading data
CANC | FBT | |
Last sale 7/28/2026 at 1:30 PM | $41.18 | $251.31 |
| Previous close 07/27/2026 | $41.10 | $246.74 |
| Consolidated volume 07/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
Create an account to view replication metrics
Join for free
CANC
is actively managed and doesn’t replicate an indexCANC | FBT | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Advertisement
Main metrics
Last update 7/28/2026 at 1:30 PM
Live
Closed
CANC | FBT | |
|---|---|---|
| Last price | $41.18 | $251.31 |
| 1D performance | +0.20% | +1.85% |
| AuM | $195.62 M | $2.76 B |
| E/R | 0.99% | 0.54% |
Characteristics
CANC | FBT | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Tema | First Trust |
| Benchmark | - | NYSE Arca Biotechnology Index |
| N° of holdings | 56 | 30 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | August 15, 2023 | June 19, 2006 |
| ESG | No | No |
Advertisement
Exposure
Countries
CANC
USA
80.59%
Switzerland
9.85%
Other
9.56%
FBT
USA
84.94%
Other
15.06%
Sectors
CANC
Healthcare
99.28%
Other
0.72%
FBT
Healthcare
99.93%
Other
0.07%
Advertisement
Diversification
CANC
Total weight of top 15 holdings out of 15
55.76%
FBT
Total weight of top 15 holdings out of 15
59.85%
Top 15 holdings
Data as of June 30, 2026
CANC
Revolution Medicines, Inc.
6.32%
Eli Lilly & Co.
5.24%
Cogent Biosciences, Inc.
4.94%
Novartis AG
4.19%
Roche Holding AG
3.93%
Legend Biotech Corp.
3.70%
Merck & Co., Inc.
3.66%
Bristol Myers Squibb Co.
3.33%
AstraZeneca PLC
3.15%
Johnson & Johnson
3.09%
AbbVie, Inc.
3.08%
Immunome, Inc.
2.87%
Exelixis, Inc.
2.85%
Nuvalent, Inc.
2.73%
IDEAYA Biosciences, Inc.
2.68%
FBT
Corcept Therapeutics, Inc.
5.66%
NeoGenomics, Inc.
5.22%
Veracyte, Inc.
5.16%
Bruker Corp.
4.33%
Alkermes Plc
4.16%
Illumina, Inc.
4.08%
Krystal Biotech, Inc.
3.85%
Natera, Inc.
3.84%
Axsome Therapeutics, Inc.
3.62%
Neurocrine Biosciences, Inc.
3.49%
Bio-Techne Corp.
3.43%
Arrowhead Pharmaceuticals, Inc.
3.31%
Exelixis, Inc.
3.27%
Biogen, Inc.
3.25%
Incyte Corp.
3.18%
Frequently asked questions about CANC and FBT
How have the CANC and FBT ETFs performed in 2026?
As of July 27, 2026, CANC is up 18.41% year-to-date (YTD), while FBT has returned 20.24%. That puts FBT better performer ahead so far this year.
Which ETF is attracting more investor money: CANC or FBT?
Year-to-date, the CANC ETF saw +$52M in flows, compared to +$1.03B for FBT.
Which ETF is more volatile: CANC or FBT?
Over the past year, CANC had a volatility of 22.71%, while FBT experienced 21.18%.
Which ETF is bigger: CANC or FBT?
As of July 27, 2026, CANC holds $195.62 M in assets under management (AUM), while FBT manages $2.76 B.
What sectors do the CANC and FBT ETFs invest in?
CANC leans toward sectors like Healthcare. Meanwhile, FBT focuses on Healthcare.
What are the top holdings of the CANC ETF and FBT ETF?
CANC top holdings include Revolution Medicines, Inc., Eli Lilly & Co. and Cogent Biosciences, Inc.. FBT holds in its top three: Corcept Therapeutics, Inc., NeoGenomics, Inc. and Veracyte, Inc..
Which ETF is more diversified: CANC or FBT?
CANC holds 56 securities with 55.76% of its assets in the top 15. FBT has 30 securities and a top 15 weight of 59.85%.
Advertisement
Latest news about CANC & FBT
Advertisement
