CANCvsBBPETF Comparison
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Tema Oncology ETF (CANC) and Virtus LifeSci Biotech Products ETF (BBP) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.79% for BBP. CANC is up 10.62% year-to-date (YTD) with +$50M in YTD flows. BBP performs worse with 6.67% YTD performance, and +$12M in YTD flows. Run a side-by-side ETF comparison of CANC and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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CANC vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | CANC BBP | +10.08%+5.15% | +5.34%+2.18% | +10.62%+6.67% | +55.67%+51.84% | n/a+65.27% | n/a+58.71% |
| Flows | CANC BBP | +$5M+$8M | +$29M+$12M | +$50M+$12M | +$70M+$27M | -+$27M | -+$17M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | CANC BBP | +23.62%+28.39% | +23.46%+24.04% | n/a+23.76% | n/a+26.19% |
| Max drawdown | CANC BBP | -7.99%-9.59% | -10.53%-9.81% | n/a-25.54% | n/a-38.24% |
| Max drawdown duration | CANC BBP | 43d48d | 32d36d | n/a292d | n/a915d |
Trading data
CANC | BBP | |
Last sale 4/27/2026 at 1:30 PM | $37.78 | $83.62 |
| Previous close 04/24/2026 | $38.36 | $84.11 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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CANC
is actively managed and doesn’t replicate an indexCANC | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
CANC | BBP | |
|---|---|---|
| Last price | $37.78 | $83.62 |
| 1D performance | -1.52% | -0.57% |
| AuM | $179.70 M | $59.56 M |
| E/R | 0.99% | 0.79% |
Characteristics
CANC | BBP | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Tema | VIRTUS Investment Partners |
| Benchmark | - | LifeSci Biotechnology Products Index |
| N° of holdings | 44 | 56 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | August 15, 2023 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
CANC
USA
85.51%
Other
14.49%
BBP
USA
89.45%
Other
10.55%
Sectors
CANC
Health Care
78.17%
Other
21.83%
BBP
Health Care
88.78%
Other
11.22%
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Diversification
CANC
Total weight of top 15 holdings out of 15
56.1%
BBP
Total weight of top 15 holdings out of 15
33.42%
Top 15 holdings
Data as of March 31, 2026
CANC
REVOLUTION MEDICINES INC
4.95%
ASTRAZENECA
4.60%
NOVARTIS
4.45%
US7711951043
4.26%
LILLY
4.20%
BRIDGEBIO PHARMA
3.94%
COGENT BIOSCIENCES
3.88%
BRISTOL-MYERS SQUIBB
3.74%
MERCK & CO INC
3.62%
IMMUNOME
3.30%
JOHNSON&JOHNSON
3.23%
NUVALENT
3.20%
CELCUITY INC
3.07%
US3723032062
2.95%
ABBVIE
2.71%
BBP
BIOCRYST PHARMACEUTICALS
2.50%
ROIVANT SCIENCES LTD
2.45%
SYNDAX PHARMACEUTICALS INC
2.40%
GILEAD SCIENCES
2.25%
GERON
2.24%
GB00BRXB0C07
2.23%
KALVISTA PHARMACEUTICALS INC
2.22%
AMGEN-T
2.20%
AXSOME THERA CMN STK
2.20%
AGIOS PHARMA/D
2.18%
BIOGEN INC
2.17%
UTD THERAPEUT
2.13%
LIGAND PHARMACEUTICALS
2.13%
BIOMARIN PHARMACEUTICAL
2.06%
EXELIXIS
2.05%
Frequently asked questions about CANC and BBP
How have the CANC and BBP ETFs performed in 2026?
As of April 24, 2026, CANC is up 10.62% year-to-date (YTD), while BBP has returned 6.67%. That puts CANC better performer ahead so far this year.
Which ETF is attracting more investor money: CANC or BBP?
Year-to-date, the CANC ETF saw +$50M in flows, compared to +$12M for BBP.
Which ETF is more volatile: CANC or BBP?
Over the past year, CANC had a volatility of 23.46%, while BBP experienced 24.04%.
Which ETF is bigger: CANC or BBP?
As of April 24, 2026, CANC holds $179.70 M in assets under management (AUM), while BBP manages $59.56 M.
What sectors do the CANC and BBP ETFs invest in?
CANC leans toward sectors like Health Care. Meanwhile, BBP focuses on Health Care.
What are the top holdings of the CANC ETF and BBP ETF?
CANC top holdings include REVOLUTION MEDICINES INC, ASTRAZENECA and NOVARTIS. BBP holds in its top three: BIOCRYST PHARMACEUTICALS, ROIVANT SCIENCES LTD and SYNDAX PHARMACEUTICALS INC.
Which ETF is more diversified: CANC or BBP?
CANC holds 54 securities with 56.1% of its assets in the top 15. BBP has 61 securities and a top 15 weight of 33.42%.
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