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BMEDvsXLVIETF Comparison

ETF 1
BMED

iShares Health Innovation Active ETF

This fund is part of
Healthcare Technology
+0.03%
VS
ETF 2
XLVI

State Street Health Care Select Sector SPDR Premium Income Fund

This fund is part of
Options Strategies
-0.1%

iShares Health Innovation Active ETF (BMED) belongs to the Healthcare Technology segment. State Street Health Care Select Sector SPDR Premium Income Fund (XLVI) is part of the Options Strategies segment. Both ETFs have the same top 3 sector exposures: and Health Care. BMED is more expensive with a Total Expense Ratio (TER) of 0.77%, versus 0.35% for XLVI. BMED is down -7.92% year-to-date (YTD) with +$4M in YTD flows. XLVI performs better with -3.01% YTD performance, and +$853K in YTD flows. Run a side-by-side ETF comparison of BMED and XLVI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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BMED vs XLVI performance and flow charts

Performance

-4.0-3.0-2.0-1.00.01.02.03.0%Apr 6Apr 13Apr 20Apr 27May 4

Cumulative Flows

-1 M-0.5 M0 MApr 6Apr 13Apr 20Apr 27May 4

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Historic performance and flows
Data as of 05/04/2026
1M3MYTD1Y3Y5Y
Perf.
BMED
XLVI
-2.92%-0.07%
-9.68%-3.94%
-7.92%-3.01%
+14.49%n/a
+14.70%n/a
-3.37%n/a
Flows
BMED
XLVI
--$1M
+$1M+$319K
+$4M+$853K
+$7M-
+$4M-
+$5M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
BMED
XLVI
+16.95%+13.38%
+15.53%n/a
+15.60%n/a
+17.55%n/a
Max drawdown
BMED
XLVI
-10.97%-8.21%
-13.52%n/a
-19.76%n/a
-33.96%n/a
Max drawdown duration
BMED
XLVI
64d64d
102dn/a
237dn/a
1586dn/a
Trading data

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BMED
XLVI
Last sale
5/5/2026 at 1:30 PM
$28.13
$24.63
Previous close
05/04/2026
$27.84
$24.54
Consolidated volume
05/04/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
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Main metrics
Last update 5/5/2026 at 1:30 PM
Live
Closed
BMED
XLVI
Last price
$28.13
$24.63
1D performance
+1.03%
+0.36%
AuM$10.04 M$11.52 M
E/R0.77%0.35%
Characteristics
BMED
XLVI
Management strategyActiveActive
ProvideriSharesState Street Investment Management
Benchmark--
N° of holdings3556
Asset class--
Trailing 12m distribution yield
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Inception dateSeptember 29, 2020July 30, 2025
ESGNoNo
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Exposure

Countries

BMED
USA
91.63%
Other
8.37%
XLVI
USA
96.44%
Other
3.56%

Sectors

BMED
Health Care
85.5%
Other
14.5%
XLVI
Health Care
97.46%
Other
2.54%
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Diversification

BMED

Total weight of top 15 holdings out of 15

61.4%
XLVI

Total weight of top 15 holdings out of 15

70.36%

Top 15 holdings

Data as of March 31, 2026
BMED
JOHNSON&JOHNSON
7.99%
US0669224778
7.13%
MERCK & CO INC
5.59%
GILEAD SCIENCES
5.48%
AMGEN-T
4.46%
EDWARDS LIFESCIENCES
4.33%
BIOGEN INC
3.36%
GUARDANT HEALTH INC
3.04%
WUXI BIOLOGICS (CAYMAN)
3.02%
METTLER TOLEDO
2.93%
VERTEX PHARMACEUTICALS
2.92%
WATERS
2.92%
CHRLS RIVER LABS
2.91%
MODERNA INC
2.79%
US04016X1019
2.54%
XLVI
LILLY
13.62%
JOHNSON&JOHNSON
11.01%
ABBVIE
7.19%
MERCK & CO INC
5.58%
UNITEDHEALTH GRP
4.58%
AMGEN-T
3.54%
THERMO FISHER SCIENTIFIC
3.45%
ABBOTT LABS
3.34%
GILEAD SCIENCES
3.23%
INTUITIVE SURGICAL
3.06%
PFIZER
2.98%
BRISTOL-MYERS SQUIBB
2.31%
DANAHER
2.23%
VERTEX PHARMACEUTICALS
2.12%
STRYKER
2.12%
Frequently asked questions about BMED and XLVI

How have the BMED and XLVI ETFs performed in 2026?

As of May 4, 2026, BMED is down -7.92% year-to-date (YTD), while XLVI has lost -3.01%. That puts XLVI better performer ahead so far this year.

Which ETF is attracting more investor money: BMED or XLVI?

Year-to-date, the BMED ETF saw +$4M in flows, compared to +$853K for XLVI.

Which ETF is bigger: BMED or XLVI?

As of May 4, 2026, BMED holds $10.04 M in assets under management (AUM), while XLVI manages $11.52 M.

What sectors do the BMED and XLVI ETFs invest in?

BMED leans toward sectors like Health Care. Meanwhile, XLVI focuses on Health Care.

What are the top holdings of the BMED ETF and XLVI ETF?

BMED top holdings include JOHNSON&JOHNSON, US0669224778 and MERCK & CO INC. XLVI holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.

Which ETF is more diversified: BMED or XLVI?

BMED holds 48 securities with 61.4% of its assets in the top 15. XLVI has 59 securities and a top 15 weight of 70.36%.

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