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BBPvsXHEETF Comparison

ETF 1
BBP

Virtus LifeSci Biotech Products ETF

This fund is part of
Tomorrow's Treatments
-2.17%
Full BBP fund page
VS
ETF 2
XHE

SPDR S&P Health Care Equipment ETF

This fund is part of
US Health Care
-2%
Full XHE fund page

Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. SPDR S&P Health Care Equipment ETF (XHE) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.35% for XHE. BBP is up 5.62% year-to-date (YTD) with +$4M in YTD flows. XHE performs worse with -9.43% YTD performance, and -$6M in YTD flows. Run a side-by-side ETF comparison of BBP and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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BBP vs XHE performance and flow charts

Performance

-8.0-6.0-4.0-2.00.02.04.06.0%Feb 11Feb 19Feb 26Mar 5Mar 12

Cumulative Flows

-2 M-1 M0 M1 M2 M3 M4 MFeb 11Feb 19Feb 26Mar 5Mar 12

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
BBP
XHE
+2.73%-4.50%
+7.35%-10.55%
+5.62%-9.43%
+41.19%-3.01%
+72.79%-9.90%
+54.18%-33.44%
Flows
BBP
XHE
+$4M-$2M
+$16M-$9M
+$4M-$6M
+$19M-$46M
+$19M-$297M
+$9M-$432M
Volatility and drawdown
3M1Y3Y5Y
Volatility
BBP
XHE
+24.64%+19.72%
+25.49%+23.64%
+23.37%+21.12%
+26.10%+24.20%
Max drawdown
BBP
XHE
-7.42%-14.50%
-17.97%-14.50%
-25.54%-32.63%
-38.24%-49.90%
Max drawdown duration
BBP
XHE
32d63d
106d63d
292d1054d
915d1652d
Trading data

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BBP
XHE
Last sale
3/13/2026 at 1:30 PM
$81.25
$79.38
Previous close
03/12/2026
$81.68
$79.80
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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BBP
XHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
BBP
XHE
Last price
$81.25
$79.38
1D performance
-0.53%
-0.53%
AuM$50.55 M$133.70 M
E/R0.79%0.35%
Characteristics
BBP
XHE
Management strategyPassivePassive
ProviderVIRTUS Investment PartnersSPDR
BenchmarkLifeSci Biotechnology Products IndexS&P Health Care Equipment Select Industry Index
N° of holdings5861
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateDecember 16, 2014January 26, 2011
ESGNoNo
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Exposure

Countries

BBP
USA
90.82%
Other
9.18%
XHE
USA
92.71%
Other
7.29%

Sectors

BBP
Health Care
88.88%
Other
11.12%
XHE
Health Care
93.87%
Other
6.13%
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Diversification

BBP

Total weight of top 15 holdings out of 15

30.11%
XHE

Total weight of top 15 holdings out of 15

30.47%

Top 15 holdings

Data as of January 31, 2026
BBP
DAY ONE BIOPHARMACEUTICALS
2.39%
DYNAVAX TECHNOLOGIES
2.39%
AMICUS THERAPEUTICS
2.25%
IOVANCE BIOTHERAPEUTICS INC
2.18%
ARDELYX
2.09%
AXSOME THERA CMN STK
2.07%
BIONTECH SE ADR
2.07%
GILEAD SCIENCES
1.90%
KRYSTAL BIOTECH INC
1.89%
HALOZYME THERAPEUTICS
1.86%
US52635N1037
1.85%
AMGEN-T
1.83%
THERAVANCE BIOPHARMA
1.80%
INCYTE
1.78%
EXELIXIS
1.77%
XHE
NEOGEN
2.63%
INTEGER HOLDINGS
2.17%
PENUMBRA
2.12%
UFP TECHNOLOGY
2.11%
AXOGEN
2.09%
OMNICELL
1.98%
LANTHEUS HOLDINGS
1.98%
BAXTER INTL
1.98%
GLAUKOS
1.97%
DEXCOM
1.94%
DENTSPLY SIRONA
1.92%
BUTTERFLY NETWORK INC
1.92%
ENVISTA HOLDINGS CORP
1.91%
STRYKER
1.88%
GLOBUS MEDICAL
1.86%
Frequently asked questions about BBP and XHE

How have the BBP and XHE ETFs performed in 2026?

As of March 11, 2026, BBP is up 5.62% year-to-date (YTD), while XHE has lost -9.43%. That puts BBP better performer ahead so far this year.

Which ETF is attracting more investor money: BBP or XHE?

Year-to-date, the BBP ETF saw +$4M in flows, compared to -$6M for XHE.

Which ETF is more volatile: BBP or XHE?

Over the past year, BBP had a volatility of 25.49%, while XHE experienced 23.64%.

Which ETF is bigger: BBP or XHE?

As of March 11, 2026, BBP holds $50.55 M in assets under management (AUM), while XHE manages $133.70 M.

What sectors do the BBP and XHE ETFs invest in?

BBP leans toward sectors like Health Care. Meanwhile, XHE focuses on Health Care.

What are the top holdings of the BBP ETF and XHE ETF?

BBP top holdings include DAY ONE BIOPHARMACEUTICALS, DYNAVAX TECHNOLOGIES and AMICUS THERAPEUTICS. XHE holds in its top three: NEOGEN, INTEGER HOLDINGS and PENUMBRA.

Which ETF is more diversified: BBP or XHE?

BBP holds 63 securities with 30.11% of its assets in the top 15. XHE has 64 securities and a top 15 weight of 30.47%.

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