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BBPvsXHEETF Comparison

ETF 1
BBP

Virtus LifeSci Biotech Products ETF

This fund is part of
Tomorrow's Treatments
-1.32%
VS
ETF 2
XHE

State Street SPDR S&P Health Care Equipment ETF

This fund is part of
US Health Care
-1.31%

Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. State Street SPDR S&P Health Care Equipment ETF (XHE) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.35% for XHE. BBP is up 6.07% year-to-date (YTD) with +$30M in YTD flows. XHE performs worse with -7.47% YTD performance, and -$535K in YTD flows. Run a side-by-side ETF comparison of BBP and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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BBP vs XHE performance and flow charts

Performance

-6.0-4.0-2.00.02.04.06.08.0%May 11May 18May 25Jun 1Jun 8

Cumulative Flows

0 M5 M10 M15 MMay 11May 18May 25Jun 1Jun 8

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Historic performance and flows
Data as of 06/10/2026
1M3MYTD1Y3Y5Y
Perf.
BBP
XHE
-3.52%+5.28%
-0.44%-0.31%
+6.07%-7.47%
+38.71%-2.05%
+55.38%-14.38%
+52.52%-34.20%
Flows
BBP
XHE
+$4M+$14M
+$26M+$4M
+$30M-$535K
+$42M-$33M
+$45M-$319M
+$38M-$384M
Volatility and drawdown
3M1Y3Y5Y
Volatility
BBP
XHE
+29.16%+25.89%
+23.94%+21.88%
+23.99%+21.73%
+26.33%+24.47%
Max drawdown
BBP
XHE
-7.76%-8.81%
-9.59%-18.20%
-25.54%-32.46%
-38.24%-49.90%
Max drawdown duration
BBP
XHE
29d52d
48d153d
292d1059d
915d1742d
Trading data

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BBP
XHE
Last sale
6/11/2026 at 2:00 PM
$85.38
$82.15
Previous close
06/10/2026
$84.63
$81.59
Consolidated volume
06/10/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of May 29, 2026
1-year trailing difference

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BBP
XHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 6/11/2026 at 2:00 PM
Live
Closed
BBP
XHE
Last price
$85.38
$82.15
1D performance
+0.88%
+0.68%
AuM$76.14 M$142.70 M
E/R0.79%0.35%
Characteristics
BBP
XHE
Management strategyPassivePassive
ProviderVIRTUS Investment PartnersState Street Investment Management
BenchmarkLifeSci Biotechnology Products IndexS&P Health Care Equipment Select Industry Index
N° of holdings5560
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateDecember 16, 2014January 26, 2011
ESGNoNo
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Exposure

Countries

BBP
USA
84.13%
Other
15.87%
XHE
USA
92.03%
Other
7.97%

Sectors

BBP
Health Care
85.97%
Other
14.03%
XHE
Health Care
89.92%
Other
10.08%
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Diversification

BBP

Total weight of top 15 holdings out of 15

45.32%
XHE

Total weight of top 15 holdings out of 15

29.69%

Top 15 holdings

Data as of April 30, 2026
BBP
ARROWHEAD PHARMACEUTICALS INC
3.17%
GB00BRXB0C07
3.17%
BIOGEN INC
3.14%
HALOZYME THERAPEUTICS
3.13%
AURINIA PHARMACEUTICALS INC
3.12%
SYNDAX PHARMACEUTICALS INC
3.12%
BIOMARIN PHARMACEUTICAL
3.05%
INCYTE
3.03%
REGENERON PHARMACEUTICALS
3.03%
BRIDGEBIO PHARMA
3.00%
SAREPTA THERAPEUTICS INC DE
2.95%
ARDELYX
2.92%
VERTEX PHARMACEUTICALS
2.85%
US07725L1026
2.83%
THERAVANCE BIOPHARMA
2.80%
XHE
STAAR SURGICAL
2.55%
GLAUKOS
2.39%
AXOGEN
2.29%
BUTTERFLY NETWORK INC
2.14%
NOVOCURE LTD
2.07%
AVANOS MEDICAL INC
2.05%
TELEFLEX
1.89%
OMNICELL
1.89%
IRHYTHM TECHNOLOGIES
1.84%
US58507V1070
1.79%
INTEGER HOLDINGS
1.78%
GLOBUS MEDICAL
1.77%
LANTHEUS HOLDINGS
1.76%
MASIMO
1.74%
LEMAITRE VASCULAR
1.73%
Frequently asked questions about BBP and XHE

How have the BBP and XHE ETFs performed in 2026?

As of June 10, 2026, BBP is up 6.07% year-to-date (YTD), while XHE has lost -7.47%. That puts BBP better performer ahead so far this year.

Which ETF is attracting more investor money: BBP or XHE?

Year-to-date, the BBP ETF saw +$30M in flows, compared to -$535K for XHE.

Which ETF is more volatile: BBP or XHE?

Over the past year, BBP had a volatility of 23.94%, while XHE experienced 21.88%.

Which ETF is bigger: BBP or XHE?

As of June 10, 2026, BBP holds $76.14 M in assets under management (AUM), while XHE manages $142.70 M.

What sectors do the BBP and XHE ETFs invest in?

BBP leans toward sectors like Health Care. Meanwhile, XHE focuses on Health Care.

What are the top holdings of the BBP ETF and XHE ETF?

BBP top holdings include ARROWHEAD PHARMACEUTICALS INC, GB00BRXB0C07 and BIOGEN INC. XHE holds in its top three: STAAR SURGICAL, GLAUKOS and AXOGEN.

Which ETF is more diversified: BBP or XHE?

BBP holds 59 securities with 45.32% of its assets in the top 15. XHE has 66 securities and a top 15 weight of 29.69%.

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